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Disease on EC 1.2.1.36 - retinal dehydrogenase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acquired Immunodeficiency Syndrome
Cutting Edge: 4-1BB Controls Regulatory Activity in Dendritic Cells through Promoting Optimal Expression of Retinal Dehydrogenase.
Adenoma
Retinoid acid receptor expression is helpful to distinguish between adenoma and well-differentiated carcinoma in the thyroid.
Alzheimer Disease
Disruption of the retinoid signalling pathway causes a deposition of amyloid beta in the adult rat brain.
Asthma
Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma.
Barrett Esophagus
The Microenvironment in Barrett's Esophagus Tissue Is Characterized by High FOXP3 and RALDH2 Levels.
Blindness
Retinal dehydrogenase 12 (RDH12) mutations in leber congenital amaurosis.
Breast Neoplasms
Profiling of the transcriptional response to all-trans retinoic acid in breast cancer cells reveals RARE-independent mechanisms of gene expression.
Carcinoma
Retinoid acid receptor expression is helpful to distinguish between adenoma and well-differentiated carcinoma in the thyroid.
Vitamin A metabolism is impaired in human ovarian cancer.
Carcinoma, Hepatocellular
Retinal dehydrogenase 5 (RHD5) attenuates metastasis via regulating HIPPO/YAP signaling pathway in Hepatocellular Carcinoma.
Cataract
Molecular Mimicry between Betaine Aldehyde Dehydrogenase of Leptospira and Retinal Dehydrogenase 1 of Human Lens: A Potential Trigger for Cataract Formation in Leptospiral Uveitis Patients.
Proteomic analysis of human age-related nuclear cataracts and normal lens nuclei.
Choanal Atresia
A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment.
Colitis
Antibody secreting cells are critically dependent on integrin ?4?7/MAdCAM-1 for intestinal recruitment and control of the microbiota during chronic colitis.
Crohn Disease
Human CD14+ macrophages in intestinal lamina propria exhibit potent antigen-presenting ability.
Cystic Fibrosis
Retinoic acid signaling regulates murine bronchial tubule formation.
Diabetes Mellitus, Type 2
Raldh3 expression in diabetic islets reciprocally regulates secretion of insulin and glucagon from pancreatic islets.
Endometrial Hyperplasia
From endometrial hyperplasia to endometrial cancer: insight into the biology and possible medical preventive measures.
Esotropia
PLXNC1 and RDH13 associated with bilateral convergent strabismus with exophthalmus in German Brown cattle.
Food Hypersensitivity
Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways.
Glomerulonephritis, IGA
Myofibroblasts acquire retinoic acid-producing ability during fibroblast-to-myofibroblast transition following kidney injury.
Heart Defects, Congenital
ALDH1A2 (RALDH2) genetic variation in human congenital heart disease.
Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse.
Hernias, Diaphragmatic, Congenital
Retinal dehydrogenase-2 is inhibited by compounds that induce congenital diaphragmatic hernias in rodents.
Ileitis
Granulocyte-macrophage colony stimulating factor blockade promotes ccr9(+) lymphocyte expansion in Nod2 deficient mice.
Infections
Upregulation of Retinal Dehydrogenase 2 in Alternatively Activated Macrophages during Retinoid-dependent Type-2 Immunity to Helminth Infection in Mice.
Insulin Resistance
Contribution of Hepatic Retinaldehyde Dehydrogenase Induction to Impairment of Glucose Metabolism by High-Fat-Diet Feeding in C57BL/6J Mice.
Retinaldehyde represses adipogenesis and diet-induced obesity.
Leber Congenital Amaurosis
Retinal dehydrogenase 12 (RDH12) mutations in leber congenital amaurosis.
Liver Cirrhosis
Retinol dehydrogenase 13 deficiency diminishes carbon tetrachloride-induced liver fibrosis in mice.
Lymphatic Metastasis
Aldehyde dehydrogenase 3A1 is robustly upregulated in gastric cancer stem-like cells and associated with tumorigenesis.
Metabolic Diseases
Vitamin A signaling and homeostasis in obesity, diabetes, and metabolic disorders.
Moyamoya Disease
Deregulation of Retinaldehyde Dehydrogenase 2 Leads to Defective Angiogenic Function of Endothelial Colony-Forming Cells in Pediatric Moyamoya Disease.
Myopia
Identification of active retinaldehyde dehydrogenase isoforms in the postnatal human eye.
Postnatal Chick Choroids Exhibit Increased Retinaldehyde Dehydrogenase Activity During Recovery From Form Deprivation Induced Myopia.
Neoplasm Metastasis
Aldehyde dehydrogenase 3A1 is robustly upregulated in gastric cancer stem-like cells and associated with tumorigenesis.
Retinal dehydrogenase 5 (RHD5) attenuates metastasis via regulating HIPPO/YAP signaling pathway in Hepatocellular Carcinoma.
Neoplasms
Aldehyde dehydrogenase 3A1 is robustly upregulated in gastric cancer stem-like cells and associated with tumorigenesis.
Development of a Retinal-Based Probe for the Profiling of Retinaldehyde Dehydrogenases in Cancer Cells.
Diverse actions of retinoid receptors in cancer prevention and treatment.
Evaluation of spice and herb as phyto-derived selective modulators of human retinaldehyde dehydrogenases using a simple in vitro method.
From endometrial hyperplasia to endometrial cancer: insight into the biology and possible medical preventive measures.
Inhibition of ALDH3A1-catalyzed oxidation by chlorpropamide analogues.
Intestinal bacteria condition dendritic cells to promote IgA production.
Investigating the Role of Missense SNPs on ALDH 1A1 mediated pharmacokinetic resistance to cyclophosphamide.
Involvement of aldehyde dehydrogenase 1A2 in the regulation of cancer stem cell properties in neuroblastoma.
Isolation and Establishment of a Highly Proliferative, Cancer Stem Cell-Like, and Naturally Immortalized Triple-Negative Breast Cancer Cell Line, KAIMRC2.
Mouse CD11bhigh lung dendritic cells have more potent capability to induce IgA than CD103+ lung dendritic cells in vitro.
Retinoic acid biosynthesis by normal human breast epithelium is via aldehyde dehydrogenase 6, absent in MCF-7 cells.
The retinal dehydrogenase/reductase retSDR1/DHRS3 gene is activated by p53 and p63 but not by mutants derived from tumors or EEC/ADULT malformation syndromes.
Nephrosis
Retinoids regulate the repairing process of the podocytes in puromycin aminonucleoside-induced nephrotic rats.
Neuroblastoma
Involvement of aldehyde dehydrogenase 1A2 in the regulation of cancer stem cell properties in neuroblastoma.
Obesity
Contribution of Hepatic Retinaldehyde Dehydrogenase Induction to Impairment of Glucose Metabolism by High-Fat-Diet Feeding in C57BL/6J Mice.
Effects of citral, a naturally occurring antiadipogenic molecule, on an energy-intense diet model of obesity.
Retinaldehyde represses adipogenesis and diet-induced obesity.
Pre-Eclampsia
Analysis of the placental tissue transcriptome of normal and preeclampsia complicated pregnancies.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3.
Prolactinoma
Reduction of retinaldehyde dehydrogenase 1 expression and production in estrogen-induced prolactinoma of rat.
Retinal Degeneration
Levels of retinoic acid and retinaldehyde dehydrogenase expression in eyes of the Mitf-vit mouse model of retinal degeneration.
retinal dehydrogenase deficiency
Rdh13 deficiency weakens carbon tetrachloride-induced liver injury by regulating Spot14 and Cyp2e1 expression levels.
Retinaldehyde dehydrogenase 1 deficiency inhibits PPAR?-mediated bone loss and marrow adiposity.
Retinoic Acid-dependent signaling pathways and lineage events in the developing mouse spinal cord.
Retinol dehydrogenase 13 deficiency diminishes carbon tetrachloride-induced liver fibrosis in mice.
Retinal Dystrophies
RDH12 retinopathy: novel mutations and phenotypic description.
Spinal Cord Injuries
Characterization of retinaldehyde dehydrogenase-2 induction in NG2-positive glia after spinal cord contusion injury.
Spinal Dysraphism
Developing with lethal RA levels: genetic ablation of Rarg can restore the viability of mice lacking Cyp26a1.
Stomach Neoplasms
Aldehyde dehydrogenase 3A1 is robustly upregulated in gastric cancer stem-like cells and associated with tumorigenesis.
Filtering High-Dimensional Methylation Marks With Extremely Small Sample Size: An Application to Gastric Cancer Data.
Teratocarcinoma
Molecular identification of a major retinoic-acid-synthesizing enzyme, a retinaldehyde-specific dehydrogenase.
Uveitis
Molecular Mimicry between Betaine Aldehyde Dehydrogenase of Leptospira and Retinal Dehydrogenase 1 of Human Lens: A Potential Trigger for Cataract Formation in Leptospiral Uveitis Patients.
Vision Disorders
Mutations in RDH12 encoding a photoreceptor cell retinol dehydrogenase cause childhood-onset severe retinal dystrophy.
Vitamin A Deficiency
Astrocytes as a regulated source of retinoic acid for the brain.
Cellular expression of retinal dehydrogenase types 1 and 2: effects of vitamin A status on testis mRNA.
Retinal dehydrogenase gene expression in stomach and small intestine of rats during postnatal development and in vitamin A deficiency.
The role of vitamin A in mammalian reproduction and embryonic development.
Vitamin A deficiency induces congenital spinal deformities in rats.