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Information on EC 1.2.1.20 - glutarate-semialdehyde dehydrogenase

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EC Tree
IUBMB Comments
The enzyme, characterized from multiple Pseudomonas strains, participates in L-lysine degradation. Unlike earlier claims, it prefers NADP+ to NAD+.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
glutarate semialdehyde dehydrogenase, gsa dehydrogenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
5-oxopentanoate + NADP+ + H2O = glutarate + NADPH + H+
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