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Disease on EC 1.17.3.2 - xanthine oxidase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abortion, Spontaneous
Cytogenetic investigation of fetuses and infants conceived through intracytoplasmic sperm injection.
Acidosis
Buffering hypercapnic acidosis worsens acute lung injury.
Effect of oxidative stress and acidosis on diaphragm contractile function.
Acne Vulgaris
Oxidative stress in acne vulgaris.
Acute Kidney Injury
An evaluation of antioxidant effects on recovery from postischemic acute renal failure.
Acute Lung Injury
Lung injury and complement activation: role of neutrophils and xanthine oxidase.
Xanthine oxidase contributes to lung leak in rats subjected to skin burn.
Adenoma
Bottom-up histogenesis of colorectal adenomas: origin in the monocryptal adenoma and initial expansion by crypt fission.
Airway Obstruction
Cytokine-mediated xanthine oxidase upregulation in chronic obstructive pulmonary disease's airways.
Alagille Syndrome
Xanthogranulomatous osteomyelitis of the humerus in a pediatric patient with Alagille syndrome: a case report and literature review.
Albuminuria
Xanthine oxidase and uric acid as independent predictors of albuminuria in patients with diabetes mellitus type 2.
Alopecia
Xanthine oxidase activity in thiopurine curative Chinese inflammatory bowel disease patients.
Aortic Aneurysm
Turner's syndrome occurring with Horner's syndrome. Seen with coarctation of the aorta and aortic aneurysm.
Aortic Coarctation
Turner's syndrome occurring with Horner's syndrome. Seen with coarctation of the aorta and aortic aneurysm.
Aortic Valve Insufficiency
Aortic dilatation resulting in chronic aortic regurgitation and complicated by aortic dissection in a patient with Turner's syndrome.
Apnea
Apnea stimulates the adaptive response to oxidative stress in elephant seal pups.
Purine nucleoside phosphorylase and xanthine oxidase activities in erythrocytes and plasma from marine, semiaquatic and terrestrial mammals.
Arteriosclerosis
The treatment of hyperuricemia.
Arthritis
The xanthine oxidase-NFAT5 pathway regulates macrophage activation and TLR-induced inflammatory arthritis.
[The effect of free radicals on the rabbit articular chondrocytes in monolayer culture]
Arthritis, Gouty
Termipaniculatones A-F, chalcone-flavonone heterodimers from Terminthia paniculata, and their protective effects on hyperuricemia and acute gouty arthritis.
Asymptomatic Infections
Posttranslational ruling of xanthine oxidase activity in bovine milk by its substrates.
Atherosclerosis
Assessment of paraoxonase 1, xanthine oxidase and glutathione peroxidase activities, nitric oxide and thiol levels in women with polycystic ovary syndrome.
Atherogenic Lipid Profile and Systolic Blood Pressure are Associated with Carotid Artery Intima-media Thickness in Children with Turner Syndrome.
Circulating mononuclear cells nuclear factor-kappa B activity, plasma xanthine oxidase, and low grade inflammatory markers in adult patients with familial hypercholesterolaemia.
Effects of garlic extract consumption on plasma and erythrocyte antioxidant parameters in atherosclerotic patients.
Harnessing hyperuricemia to atherosclerosis and understanding its mechanistic dependence.
Increased plasma xanthine oxidase activity is related to nuclear factor kappa beta activation and inflammatory markers in familial combined hyperlipidemia.
Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis.
Xanthine oxidase inhibitor tungsten prevents the development of atherosclerosis in ApoE knockout mice fed a Western-type diet.
Bicuspid Aortic Valve Disease
Endarteritis of the aortic arch in Turner's syndrome with cystic degeneration of the aorta.
Blister
[XO karyotype state: primordial germ cells and blisters of the neck]
Bone Diseases, Metabolic
Xanthogranulomatous osteomyelitis of the humerus in a pediatric patient with Alagille syndrome: a case report and literature review.
Bone Resorption
Xanthine oxidase mediates cytokine-induced, but not hormone-induced bone resorption.
Brachydactyly
Limb anomalies in chromosomal aberrations.
Brain Edema
Xanthine oxidase is not a major source of free radicals in focal cerebral ischemia.
Xanthine oxidase-derived hydrogen peroxide contributes to ischemia reperfusion-induced edema in gerbil brains.
Brain Injuries
Protective mechanism of grape seed oil on carbon tetrachloride-induced brain damage in ?-irradiated rats.
The effect of infusing hypoxanthine or xanthine on hypoxic-ischemic brain injury in rabbits.
Xanthine oxidase does not contribute to apoptosis after brain hypoxia-ischemia in immature rabbits.
Xanthine oxidase is not a major source of free radicals in focal cerebral ischemia.
Brain Ischemia
No conversion of xanthine dehydrogenase to oxidase in canine cerebral ischemia.
X chromosome dosage and the response to cerebral ischemia.
Xanthine oxidase is not a major source of free radicals in focal cerebral ischemia.
Breast Neoplasms
Reactive oxygen species derived from xanthine oxidase interrupt dimerization of breast cancer resistance protein, resulting in suppression of uric acid excretion to the intestinal lumen.
The emerging role of xanthine oxidase inhibition for suppression of breast cancer cell migration and metastasis associated with hypercholesterolemia.
Carcinogenesis
Effects of aqueous green tea extract on activities of DNA turn-over enzymes in cancerous and non-cancerous human gastric and colon tissues.
Xanthine Oxidase/Dehydrogenase Activity as a Source of Oxidative Stress in Prostate Cancer Tissue.
Carcinoma
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part I: Quantitation of superoxide dismutase, catalase, glutathione peroxidase and xanthine oxidase.
Carcinoma, Embryonal
De novo X-chromosome inactivation in somatic hybrid cells between the XO mouse embryonal carcinoma cell and XY rat lymphocyte.
Requirement of mitoses for the reversal of X-inactivation in cell hybrids between murine embryonal carcinoma cells and normal female thymocytes.
Variable X chromosome inactivation patterns in near-tetraploid murine EC x somatic cell hybrid cells differentiated in vitro.
Carcinoma, Hepatocellular
Dose-dependent regulation of superoxide anion on the proliferation, differentiation, apoptosis and necrosis of human hepatoma cells: the role of intracellular Ca 2+.
Imbalance of purine metabolism in hepatomas of different growth rates as expressed in behavior of xanthine oxidase (EC 1.2.3.2).
Inhibitory effect of gingerol on the proliferation and invasion of hepatoma cells in culture.
Carcinoma, Squamous Cell
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part I: Quantitation of superoxide dismutase, catalase, glutathione peroxidase and xanthine oxidase.
Cardiomyopathies
Allopurinol improves myocardial efficiency in patients with idiopathic dilated cardiomyopathy.
Chronic treatment with allopurinol boosts survival and cardiac contractility in murine postischemic cardiomyopathy.
Inappropriate prescription of allopurinol and febuxostat and risk of adverse events in the elderly: results from the REPOSI registry.
Xanthine Oxidase Inhibition Prevents Atrial Fibrillation in a Canine Model of Atrial Pacing-Induced left Ventricular Dysfunction.
Cardiomyopathy, Dilated
Allopurinol improves myocardial efficiency in patients with idiopathic dilated cardiomyopathy.
Cardiotoxicity
Purine versus non-purine xanthine oxidase inhibitors against cyclophosphamide-induced cardiac and bone marrow toxicity in rats.
Xanthine oxidase inhibition attenuates doxorubicin-induced cardiotoxicity in mice.
Cardiovascular Diseases
An evidence-based review on urate-lowering treatments: implications for optimal treatment of chronic hyperuricemia.
Evaluation of enzymes inhibition activities of medicinal plant from Burkina Faso.
High-cholesterol diet increases xanthine oxidase and decreases nitric oxide synthase activities in erythrocytes from rats.
Inhibitors of xanthine oxidase: scaffold diversity and structure-based drug design.
Is Xanthine oxidase activity in polycystic ovary syndrome associated with inflammatory and cardiovascular risk factors?
Plasma Xanthine Oxidase Activity Is Predictive of Cardiovascular Disease in Patients with Chronic Kidney Disease, Independently of Uric Acid Levels.
Role of Community Pharmacies for the Detection of Potentially Inappropriate Xanthine Oxidase Inhibitor Prescriptions.
The role of urate and xanthine oxidase inhibitors in cardiovascular disease.
Xanthine oxidase inhibition by 1,3-dipropyl-8-sulfophenylxanthine (DPSPX), an antagonist of adenosine receptors.
Xanthine oxidase-derived extracellular superoxide anions stimulate activator protein 1 activity and hypertrophy in human vascular smooth muscle via c-Jun N-terminal kinase and p38 mitogen-activated protein kinases.
Cataract
Xanthine oxidase activity in patients with age-related cataract associated with hypertension.
Cerebral Infarction
Evaluation of Antioxidant and Cerebroprotective Effect of Medicago sativa Linn. against Ischemia and Reperfusion Insult.
Chemical and Drug Induced Liver Injury
Safety profiles of new xanthine oxidase inhibitors: A post-marketing study.
Cholera
Biphasic alterations in cardiac beta-adrenoceptor signal transduction mechanism due to oxyradicals.
Cholestasis
Serum xanthine oxidase in human liver disease.
The effect of ursodeoxycholic acid on oxidative stress level and DNase activity in rat liver after bile duct ligation.
The impact of hepatic xanthine oxidase and xanthine dehydrogenase activities on liver function in chronic cholestasis.
Cholestasis, Extrahepatic
Plasma superoxide radical in jaundiced patients and role of xanthine oxidase.
Chondrocalcinosis
Dose-response relationship between lower serum magnesium level and higher prevalence of knee chondrocalcinosis.
Colitis, Ulcerative
Near real-time determination of metabolic parameters for unquenched 6-mercaptopurine and xanthine oxidase samples using capillary electrophoresis.
Colonic Neoplasms
Endophytic naphthopyrone metabolites are co-inhibitors of xanthine oxidase, SW1116 cell and some microbial growths.
Color Vision Defects
Brief historical note: the concept of "gonadal dysgenesis".
Coma
Quantifying the Optical and Physical Consequences of Daily Cleaning on Conventional and Wavefront-guided Scleral Lenses.
Congenital Abnormalities
Radiological and clinical analysis of Madelung's deformity in children.
Contracture
Effect of reactive oxygen species on K+ contractures in the rat diaphragm.
Coronary Artery Disease
The influence of febuxostat on coronary artery endothelial dysfunction in patients with coronary artery disease: A phase 4 randomized, placebo-controlled, double-blind, crossover trial.
Coronary Disease
Angiotensin II induces endothelial xanthine oxidase activation: role for endothelial dysfunction in patients with coronary disease.
COVID-19
Xanthine Oxidase-Induced Inflammatory Responses in Respiratory Epithelial Cells: A Review in Immunopathology of COVID-19.
Craniosynostoses
Turner-mongolism polysyndrome. Review of the first eight known cases.
Crohn Disease
Crohn's disease in Turner's syndrome with X-chromosomal mosaicism of 45 XO and 47 XXX.
Intestinal oxidative damage in inflammatory bowel disease: semi-quantification, localization, and association with mucosal antioxidants.
Near real-time determination of metabolic parameters for unquenched 6-mercaptopurine and xanthine oxidase samples using capillary electrophoresis.
Cryptorchidism
Seminoma in a 12-year-old male with 46 XY/45 XO karyotype.
Cysts
Endarteritis of the aortic arch in Turner's syndrome with cystic degeneration of the aorta.
Diabetes Mellitus
Activity of xanthine oxidase in plasma correlates with indices of insulin resistance and liver dysfunction in patients with type 2 diabetes mellitus and metabolic syndrome: A pilot exploratory study.
Xanthine oxidase and uric acid as independent predictors of albuminuria in patients with diabetes mellitus type 2.
[45, XO Turner's syndrome associated with menarche and diabetes mellitus]
[Duodenal angiodysplasia and Turner's syndrome. Case report]
Diabetes Mellitus, Type 2
Activity of xanthine oxidase in plasma correlates with indices of insulin resistance and liver dysfunction in patients with type 2 diabetes mellitus and metabolic syndrome: A pilot exploratory study.
Diabetes, Gestational
Oxidant status in maternal and cord plasma and placental tissue in gestational diabetes.
Diabetic Angiopathies
Confirmation of superoxide generation via xanthine oxidase in streptozotocin-induced diabetic mice.
Diabetic Cardiomyopathies
Xanthine oxidase inhibitor allopurinol attenuates the development of diabetic cardiomyopathy.
Diabetic Nephropathies
NON-PURINE SELECTIVE XANTHINE OXIDASE INHIBITOR AMELIORATES GLOMERULAR ENDOTHELIAL INJURY IN InsAkita DIABETIC MICE.
Disorder of Sex Development, 46,XY
Male pseudohermaphroditism with XO chromosomal constitution on bone-marrow cells.
Premature gonadal failure in female dogs and cats.
Disorders of Sex Development
Premature gonadal failure in female dogs and cats.
Down Syndrome
Antenatal diagnosis of coarctation of the aorta: a multicenter experience.
Sensitivity of multiple first trimester sonomarkers in fetal aneuploidy detection.
Thickened nuchal fold in fetuses not at risk for aneuploidy.
[Association of trisomy 21 and gonosomal trisomy. Apropos of 2 cases]
Duodenal Ulcer
Histamine, xanthine oxidase generated oxygen-derived free radicals and Helicobacter pylori in gastroduodenal inflammation and ulceration.
Dupuytren Contracture
Free radicals and Dupuytren's contracture.
Eosinophilia
Safety profiles of new xanthine oxidase inhibitors: A post-marketing study.
Esophageal Neoplasms
Molybdenum: an essential trace element.
Essential Hypertension
Circulating purine compounds, uric acid, and xanthine oxidase/dehydrogenase relationship in essential hypertension and end stage renal disease.
Different pathomechanisms of essential and obesity-associated hypertension in adolescents.
Eye Injuries
Differential in vitro inhibition studies of some cerium vanadate derivatives on xanthine oxidase.
Fasciculation
Lipid peroxidation and changes in cytochrome c oxidase and xanthine oxidase activity in organophosphorus anticholinesterase induced myopathy.
Fragile X Syndrome
Differentiation of primordial germ cells from premature ovarian insufficiency-derived induced pluripotent stem cells.
Gastritis
Histamine, xanthine oxidase generated oxygen-derived free radicals and Helicobacter pylori in gastroduodenal inflammation and ulceration.
Glomerulonephritis, IGA
The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model.
Glucose Intolerance
Sodium acetate prevents nicotine-induced cardiorenal dysmetabolism through uric acid/creatine kinase-dependent pathway.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
Glucose-6-phosphate dehydrogenase deficiency in an XO individual.
Influence of Oxidative Stress Biomarkers and Genetic Polymorphisms on the Clinical Severity of Hydroxyurea-Free Senegalese Children with Sickle Cell Anemia.
Glucosephosphate Dehydrogenase Deficiency
Glucose-6-phosphate dehydrogenase deficiency in an XO individual.
Influence of Oxidative Stress Biomarkers and Genetic Polymorphisms on the Clinical Severity of Hydroxyurea-Free Senegalese Children with Sickle Cell Anemia.
Gonadal Dysgenesis
Anorexia nervosa and gonadal dysgenesis. Further evidence of a relationship.
Gonadal dysgenesis in a newborn with XO karyotype.
Intersexual phenotypes and sex chromosome complements of five South American opossums (Monodelphis domestica).
Perinatal oocyte loss in XO mice and its implications for the aetiology of gonadal dysgenesis in XO women.
Pregnancies following ovum donation in gonadal dysgenesis.
The influence of age and sex on the metabolism of testosterone.
X-chromosome inactivation may explain the difference in viability of XO humans and mice.
[Etiological, clinical and hormonal characteristics of a group of patients with permanent hypogonadism]
[Gonadal dysgenesis with hemaphroditism in cases with XX and XO sex chromosome constitution]
[Gonadal dysgenesis with karyotype XO in the neonatal age. Long-term study with karyotype studies]
[PURE GONADAL DYSGENESIS WITH XO KARYOTYPE.]
[The syndrome of multiple malformations associated with gonadal dysgenesis (Turner syndrome) with XO chromosome formula.]
Gonadoblastoma
Coexistence of hereditary angioedema and Turner's syndrome.
Ultrastructure of gonadoblastoma.
Gout
2-styrylchromones as novel inhibitors of xanthine oxidase. A structure-activity study.
3,4-Dihydroxy-5-nitrobenzaldehyde (DHNB) is a potent inhibitor of xanthine oxidase: A potential therapeutic agent for treatment of hyperuricemia and gout.
Anti-Gouty Arthritis and Antihyperuricemia Effects of Sunflower (Helianthus annuus) Head Extract in Gouty and Hyperuricemia Animal Models.
Antioxidant and xanthine oxidase inhibitory properties and LC-MS/MS identification of compoundsof ethanolic extract from Mulberry leaves.
Cardiovascular Safety of Urate Lowering Therapies.
Characterization of the xanthine oxidase inhibitory activity of alk(en)yl phenols and related compounds.
Cleroda-4(18),13-dien-15,16-olide as novel xanthine oxidase inhibitors: An integrated in silico and in vitro study.
Differential in vitro inhibition studies of some cerium vanadate derivatives on xanthine oxidase.
Discovery of 2-phenylthiazole-4-carboxylic acid, a novel and potent scaffold as xanthine oxidase inhibitors.
Drug Interaction Between Febuxostat and Thiopurine Antimetabolites: A Review of the FDA Adverse Event Reporting System and Medical Literature.
Effects of extracts from Corylopsis coreana Uyeki (Hamamelidaceae) flos on xanthine oxidase activity and hyperuricemia.
Effects of Temperature on the Composition and Xanthine Oxidase Inhibitory Activities of Caffeic Acid Roasting Products.
Evaluation of antigout activity of Phyllanthus emblica fruit extracts on potassium oxonate-induced gout rat model.
Evaluation of enzymes inhibition activities of medicinal plant from Burkina Faso.
Flavones scaffold of Chromolaena odorata as a potential xanthine oxidase inhibitor: Induced Fit Docking and ADME studies.
Flavonoid glycosides isolated from unique legume plant extracts as novel inhibitors of xanthine oxidase.
Guava leaves polyphenolics-rich extract inhibits vital enzymes implicated in gout and hypertension in vitro.
High-performance liquid chromatography coupled with post-column dual-bioactivity assay for simultaneous screening of xanthine oxidase inhibitors and free radical scavengers from complex mixture.
Identification of a potent xanthine oxidase inhibitor from oxidation of caffeic acid.
Identification of crypto- and neochlorogenic lactones as potent xanthine oxidase inhibitors in roasted coffee beans.
Identification of the biologically active constituents of Camellia japonica leaf and anti-hyperuricemic effect in vitro and in vivo.
Improving cardiovascular and renal outcomes in gout: what should we target?
In vitro and in silico pharmaceutical activities of the methylated cyclic pentapeptide, persipeptides.
In vitro and in silico xanthine oxidase inhibitory activity of selected phytochemicals widely present in various edible plants.
Inappropriate prescription of allopurinol and febuxostat and risk of adverse events in the elderly: results from the REPOSI registry.
Inhibition of xanthine oxidase by catechins from tea (Camellia sinensis).
Inhibitors of xanthine oxidase: scaffold diversity and structure-based drug design.
Isolation, characterization, and xanthine oxidase inhibitory activities of flavonoids from the leaves of Perilla frutescens.
Kinetic study on the inhibition of xanthine oxidase by extracts from two selected Algerian plants traditionally used for the treatment of inflammatory diseases.
Molecular mechanism of an adverse drug-drug interaction of allopurinol and furosemide in gout treatment.
Mori Ramulus (Chin.Ph.)-the Dried Twigs of Morus alba L./Part 1: Discovery of Two Novel Coumarin Glycosides from the Anti-Hyperuricemic Ethanol Extract.
Natural Products and Extracts as Xantine Oxidase Inhibitors - A Hope for Gout Disease?
S-allyl cysteine as potent anti-gout drug: Insight into the xanthine oxidase inhibition and anti-inflammatory activity.
Screening of Potential Xanthine Oxidase Inhibitors in Gnaphalium hypoleucum DC. by Immobilized Metal Affinity Chromatography and Ultrafiltration-Ultra Performance Liquid Chromatography-Mass Spectrometry.
Screening of xanthine oxidase inhibitors in complex mixtures using online HPLC coupled with postcolumn fluorescence-based biochemical detection.
Selectivity of febuxostat, a novel non-purine inhibitor of xanthine oxidase/xanthine dehydrogenase.
Standardization and xanthine oxidase inhibitory potential of Zanthoxylum armatum fruits.
Synthesis and evaluation of hydroxychalcones as multifunctional non-purine xanthine oxidase inhibitors for the treatment of hyperuricemia.
Synthesis, structure-activity relationships, and mechanistic studies of 5-arylazo-tropolone derivatives as novel xanthine oxidase (XO) inhibitors.
The inhibitory kinetics and mechanism of dietary vitamins D3 and B2 on xanthine oxidase.
The potential role for xanthine oxidase inhibition in major intra-abdominal surgery.
Two 6-(propan-2-yl)-4-methyl-morpholine-2,5-diones as new non-purine xanthine oxidase inhibitors and anti-inflammatory agents.
Xanthine Oxidase and Transforming Growth Factor Beta-activated Kinase 1: Potential Targets for Gout Intervention.
Xanthine oxidase inhibiting effects of noni (Morinda citrifolia) fruit juice.
Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice.
Xanthine oxidase inhibitors: patent landscape and clinical development (2015-2020).
Xanthine oxidase inhibitory activity of northeastern North American plant remedies used for gout.
Xanthine oxidase inhibitory activity of the methanolic extracts of selected Jordanian medicinal plants.
Xanthine Oxidase Inhibitory and Molecular Docking Studies on Pyrimidones.
Xanthine oxidase inhibitory peptides derived from tuna protein: virtual screening, inhibitory activity, and molecular mechanisms.
[Allopurinol and its role in the treatment of sarcopenia].
Granuloma
Induction of nitric oxide synthesis and xanthine oxidase and their roles in the antimicrobial mechanism against Salmonella typhimurium infection in mice.
Head and Neck Neoplasms
Do CO2 and oxidative stress induce cancer?: a brief study about the evaluation of PON 1, CAT, CA and XO enzyme levels on head and neck cancer patients.
Heart Diseases
Xanthine oxidase inhibitor, febuxostat ameliorates the high salt intake-induced cardiac hypertrophy and fibrosis in Dahl salt-sensitive rats.
Heart Failure
Allopurinol and global left myocardial function in heart failure patients.
Allopurinol improves myocardial efficiency in patients with idiopathic dilated cardiomyopathy.
Allopurinol, Xanthine Oxidase, and Cardiac Ischemia.
Chronic xanthine oxidase inhibition following myocardial infarction in rabbits: effects of early versus delayed treatment.
Delayed treatment effects of xanthine oxidase inhibition on systolic overload-induced left ventricular hypertrophy and dysfunction.
Disproportionate enhancement of myocardial contractility by the xanthine oxidase inhibitor oxypurinol in failing rat myocardium.
Effect of Allopurinol on Myocardial Energy Metabolism in Chronic Heart Failure Rats After Myocardial Infarct.
Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic uncoupling in the failing heart.
Impact of oxypurinol in patients with symptomatic heart failure. Results of the OPT-CHF study.
Inappropriate prescription of allopurinol and febuxostat and risk of adverse events in the elderly: results from the REPOSI registry.
Novel insights into interactions between mitochondria and xanthine oxidase in acute cardiac volume overload.
The treatment of hyperuricemia.
Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol.
Uric acid and xanthine oxidase in heart failure - Emerging data and therapeutic implications.
Xanthine oxidase inhibition improves left ventricular dysfunction in dilated cardiomyopathic hamsters.
Xanthine Oxidase Inhibition Preserves Left Ventricular Systolic but not Diastolic Function in Cardiac Volume Overload.
Hemophilia B
Hemophilia B in a phenotypically normal girl with XX (ring) XO mosaicism.
Hepatitis
2-styrylchromones as novel inhibitors of xanthine oxidase. A structure-activity study.
Hepatitis, Chronic
Serum xanthine oxidase in human liver disease.
Hypercholesterolemia
The emerging role of xanthine oxidase inhibition for suppression of breast cancer cell migration and metastasis associated with hypercholesterolemia.
Hyperemia
Vascular dysfunction and oxidative stress caused by acute formaldehyde exposure in female adults.
Hyperglycemia
Exposure of human keratinocytes to ischemia, hyperglycemia and their combination induces oxidative stress via the enzymes inducible nitric oxide synthase and xanthine oxidase.
Xanthine Oxidase Inhibitor Febuxostat Exerts an Anti-Inflammatory Action and Protects against Diabetic Nephropathy Development in KK-Ay Obese Diabetic Mice.
Hyperinsulinism
Effect of serum insulin on the association between hyperuricemia and incident heart failure.
Hyperlipidemias
Pivotal role of xanthine oxidase in the initiation of tubulointerstitial renal injury in rats with hyperlipidemia.
Hyperlipoproteinemias
[Study of the level of lipids in the blood serum of patients with Shereshevsky-Turner syndrome]
Hypertension
2-styrylchromones as novel inhibitors of xanthine oxidase. A structure-activity study.
Allopurinol does not Decrease Blood Pressure or Prevent the Development of Hypertension in the Doca-Salt Rat Model.
Aortic Dissecting Aneurysm with a Bicuspid Aortic Valve in Turner's Syndrome: Report of a Case.
Circulating purine compounds, uric acid, and xanthine oxidase/dehydrogenase relationship in essential hypertension and end stage renal disease.
Different pathomechanisms of essential and obesity-associated hypertension in adolescents.
Febuxostat, a novel xanthine oxidoreductase inhibitor, improves hypertension and endothelial dysfunction in spontaneously hypertensive rats.
Guava leaves polyphenolics-rich extract inhibits vital enzymes implicated in gout and hypertension in vitro.
Inhibitors of xanthine oxidase: scaffold diversity and structure-based drug design.
Long-term inhibition of xanthine oxidase by febuxostat does not decrease blood pressure in deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
Role of xanthine oxidase in dexamethasone-induced hypertension in rats.
The treatment of hyperuricemia.
Xanthine oxidase activation in mild gestational hypertension.
Xanthine oxidase inhibition by 1,3-dipropyl-8-sulfophenylxanthine (DPSPX), an antagonist of adenosine receptors.
Xanthine Oxidase Inhibition by Febuxostat in Macrophages Suppresses Angiotensin II-Induced Aortic Fibrosis.
Xanthine oxidase inhibitor febuxostat reduces atrial fibrillation susceptibility by inhibition of oxidized CaMKII in Dahl salt-sensitive rats.
Xanthine oxidase mediates hypoxia-inducible factor-2? degradation by intermittent hypoxia.
[Duodenal angiodysplasia and Turner's syndrome. Case report]
Hypertension, Pulmonary
Contribution of xanthine oxidase-derived superoxide to chronic hypoxic pulmonary hypertension in neonatal rats.
Generation of oxidative stress contributes to the development of pulmonary hypertension induced by hypoxia.
Perinatal changes in superoxide generation in the ovine lung: Alterations associated with increased pulmonary blood flow.
Hyperthyroidism
The Effect of Experimental Thyroid Dysfunction on Markers of Oxidative Stress in Rat Pancreas.
The role of allopurinol on oxidative stress in experimental hyperthyroidism.
Hypertrophy, Right Ventricular
Generation of oxidative stress contributes to the development of pulmonary hypertension induced by hypoxia.
Hypogonadism
The phytohemagglutinin response of human peripheral blood lymphocytes as a function of donor age: a re-examination using BrdU-Hoechst flow cytometry.
hypoxanthine phosphoribosyltransferase deficiency
The renal phenotype of allopurinol-treated HPRT-deficient mouse.
Hypoxia-Ischemia, Brain
The effect of infusing hypoxanthine or xanthine on hypoxic-ischemic brain injury in rabbits.
Ichthyosis
Sex-linked ichthyosis in XO gonadal dysgenesis.
Ichthyosis, X-Linked
Dosage of the Sts gene in the mouse.
Infarction, Middle Cerebral Artery
X chromosome dosage and the response to cerebral ischemia.
Infections
A Rare Case Report on Xanthogranulomatous Osteomyelitis of Hip Mimicking Tuberculosis and Review of Literature.
Dependence on O2- generation by xanthine oxidase of pathogenesis of influenza virus infection in mice.
Hepatic xanthine oxidase activity and purine nucleosides levels as physiological mediators to analyze a subcutaneous treatment with (PhSe)2 in mice infected by Toxoplasma gondii.
Induction of nitric oxide synthesis and xanthine oxidase and their roles in the antimicrobial mechanism against Salmonella typhimurium infection in mice.
Involvement of xanthine oxidase activity with oxidative and inflammatory renal damage in silver catfish experimentally infected with Streptococcus agalactiae: Interplay with reactive oxygen species and nitric oxide.
Pathogenesis of cytomegalovirus-associated pneumonitis in ICR mice: possible involvement of superoxide radicals.
Protective effect of n-acetylcysteine in a model of influenza infection in mice.
Role of Host Xanthine Oxidase in Infection Due to Enteropathogenic and Shiga-Toxigenic Escherichia coli.
Role of host xanthine oxidase in infection due to enteropathogenic and Shiga-toxigenic Escherichia coli.
Role of xanthine oxidase activation and reduced glutathione depletion in rhinovirus induction of inflammation in respiratory epithelial cells.
Superoxide radical is involved in the sclerotial differentiation of filamentous phytopathogenic fungi: identification of a fungal xanthine oxidase.
Temporal pattern changes in duodenal protein tyrosine nitration events in response to Eimeria acervulina infection in chickens.
Urine xanthine oxidase activity in urinary tract infection.
Xanthine oxidase activity affects pro-oxidative and pro-inflammatory profiles in spleen of silver catfish experimentally infected with Aeromonas caviae.
Infertility
Fertility, sex determination, and the X chromosome.
Generation of an induced pluripotent stem cell line from chorionic villi of a Turner syndrome spontaneous abortion.
Haldane's rule and heterogametic female and male sterility in the mouse.
Infertility and multiple urogenital abnormalities in a male with mosaic 46,XY/45,XO/47,XXY karyotype and mixed phenotype.
Premature ovarian insufficiency in the XO female mouse on the C57BL/6J genetic background.
Sterility associated with an XO karyotype in a Belgian mare.
Sterility associated with an XO karyotype in a miniature horse mare.
The significance of the XO syndrome in infertility of the mare.
Infertility, Male
Oxidative stress and male infertility.
Sex-ratio meiotic drive in Drosophila simulans is related to equational nondisjunction of the Y chromosome.
Inflammatory Bowel Diseases
Xanthine oxidase activity in thiopurine curative Chinese inflammatory bowel disease patients.
Influenza, Human
Dependence on O2- generation by xanthine oxidase of pathogenesis of influenza virus infection in mice.
Hemagglutination by influenza virus; the XO phase of influenza A virus.
Protective effect of n-acetylcysteine in a model of influenza infection in mice.
Insulin Resistance
Activity of xanthine oxidase in plasma correlates with indices of insulin resistance and liver dysfunction in patients with type 2 diabetes mellitus and metabolic syndrome: A pilot exploratory study.
Atherogenic Lipid Profile and Systolic Blood Pressure are Associated with Carotid Artery Intima-media Thickness in Children with Turner Syndrome.
Enhanced hepatic glycogen synthesis and suppressed adenosine deaminase activity by lithium attenuates hepatic triglyceride accumulation in nicotine-exposed rats.
Increased plasma xanthine oxidase activity is related to nuclear factor kappa beta activation and inflammatory markers in familial combined hyperlipidemia.
Is Xanthine oxidase activity in polycystic ovary syndrome associated with inflammatory and cardiovascular risk factors?
Sodium acetate prevents nicotine-induced cardiorenal dysmetabolism through uric acid/creatine kinase-dependent pathway.
Weight loss, xanthine oxidase and serum urate levels: A prospective, longitudinal study of obese patients.
Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice.
Xanthine oxidase inhibition by febuxostat attenuates stress-induced hyperuricemia, glucose dysmetabolism, and prothrombotic state in mice.
Intellectual Disability
Molybdenum: an essential trace element.
Turner-mongolism polysyndrome. Review of the first eight known cases.
Joint Diseases
[The effect of free radicals on the rabbit articular chondrocytes in monolayer culture]
Keratoconus
A comparison of the visual acuity outcome between Clearkone and RGP lenses.
Quantifying the Optical and Physical Consequences of Daily Cleaning on Conventional and Wavefront-guided Scleral Lenses.
Kidney Failure, Chronic
Inappropriate prescription of allopurinol and febuxostat and risk of adverse events in the elderly: results from the REPOSI registry.
Klinefelter Syndrome
Chromatin-negative Klinefelter's syndrome with focal megalencephaly.
Comparative cephalometric analysis in patients with X-chromosome aneuploidy.
Human molecular cytogenetics: diagnosis, prognosis, and disease management.
Infertility and multiple urogenital abnormalities in a male with mosaic 46,XY/45,XO/47,XXY karyotype and mixed phenotype.
XXY syndrome XY XO mosaicism and acentric chromosomal fragments in male schizophrenics.
Lens Subluxation
Molybdenum: an essential trace element.
Leukemia
Characterization of two newly established EBV-containing lymphoblastoid cell lines from patients with myeloid leukemias.
Near real-time determination of metabolic parameters for unquenched 6-mercaptopurine and xanthine oxidase samples using capillary electrophoresis.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Chronic myelogenous leukemia presenting in the blastic phase and its association with a 45 XO Ph1 karyotype.
Chronic myelogenous leukemia. Association with 45 XO Philadelphia chromosome karyotype and prolonged survival.
Males with chronic myeloid leukemia and the 45, XO, Ph1 chromosome pattern.
[Juvenile chronic myelocytic leukemia associated with neurofibromatosis and 45, XO karyotype (author's transl)]
Leukemia, Myelomonocytic, Chronic
Characterization of two newly established EBV-containing lymphoblastoid cell lines from patients with myeloid leukemias.
Liver Diseases
Activity of xanthine oxidase in plasma correlates with indices of insulin resistance and liver dysfunction in patients with type 2 diabetes mellitus and metabolic syndrome: A pilot exploratory study.
Salivary clearance and urinary metabolic pattern of caffeine in healthy children and in pediatric patients with hepatocellular diseases.
Serum xanthine oxidase in human liver disease.
Simultaneous liver and lung injury following gut ischemia is mediated by xanthine oxidase.
Lung Diseases
Detection of xanthine oxidase activity products by EPR and HPLC in bronchoalveolar lavage fluid from patients with chronic obstructive pulmonary disease.
Lung Injury
FNLP injures endotoxin-primed rat lung by neutrophil-dependent and -independent mechanisms.
Gut ischemia mediates lung injury by a xanthine oxidase-dependent neutrophil mechanism.
Hyperoxia and xanthine dehydrogenase/oxidase activities in rat lung and heart.
Lung injury after hepatoenteric ischemia-reperfusion: role of xanthine oxidase.
PentaLyte decreases lung injury after aortic occlusion-reperfusion.
Xanthine oxidase promotes neutrophil sequestration but not injury in hyperoxic lungs.
Lymphangioma, Cystic
Hygroma of the neck in XO abortuses. Report of two cases.
The significance of cystic hygroma in fetuses.
Malaria
Levels and interactions of plasma xanthine oxidase, catalase and liver function parameters in Nigerian children with Plasmodium falciparum infection.
Malaria inflammation by xanthine oxidase-produced reactive oxygen species.
The impact of xanthine oxidase (XO) on hemolytic diseases.
Malaria, Cerebral
Malaria inflammation by xanthine oxidase-produced reactive oxygen species.
Metabolic Syndrome
Activity of xanthine oxidase in plasma correlates with indices of insulin resistance and liver dysfunction in patients with type 2 diabetes mellitus and metabolic syndrome: A pilot exploratory study.
An evidence-based review on urate-lowering treatments: implications for optimal treatment of chronic hyperuricemia.
Inhibitory effects of various solvent extracts from Rhamnus frangula leaves on some inflammatory and metabolic enzymes.
Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis.
Muscular Atrophy
Inhibition of xanthine oxidase by allopurinol prevents skeletal muscle atrophy: role of p38 MAPKinase and E3 ubiquitin ligases.
Redox regulation of E3 ubiquitin ligases and their role in skeletal muscle atrophy.
Muscular Diseases
Lipid peroxidation and changes in cytochrome c oxidase and xanthine oxidase activity in organophosphorus anticholinesterase induced myopathy.
Myocardial Infarction
Allopurinol therapy of ischemic heart disease with infarct extension.
Chronic treatment with allopurinol boosts survival and cardiac contractility in murine postischemic cardiomyopathy.
Chronic xanthine oxidase inhibition following myocardial infarction in rabbits: effects of early versus delayed treatment.
Synthesis and characterization of CAPE derivatives as xanthine oxidase inhibitors with radical scavenging properties.
The potential role for xanthine oxidase inhibition in major intra-abdominal surgery.
Myocardial Ischemia
Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase--what role in myocardial ischemia and reperfusion?
Ischemic heart diseases in Egypt: role of xanthine oxidase system and ischemia-modified albumin.
Myocardial Reperfusion Injury
Hydrogen peroxide mediates reperfusion injury in the isolated rat heart.
Myocardial Stunning
Selective effects of oxygen free radicals on excitation-contraction coupling in ventricular muscle. Implications for the mechanism of stunned myocardium.
Neoplasm Metastasis
The emerging role of xanthine oxidase inhibition for suppression of breast cancer cell migration and metastasis associated with hypercholesterolemia.
Neoplasms
2-styrylchromones as novel inhibitors of xanthine oxidase. A structure-activity study.
A novel cancer therapy based on oxygen radicals.
A novel strategy for treatment of cancer cachexia targeting xanthine oxidase in the brain.
Adenosine deaminase and xanthine oxidase activities in bladder washing fluid from patients with bladder cancer: a preliminary study.
Adenosine deaminase, 5'-nucleotidase, xanthine oxidase, superoxide dismutase, and catalase activities in gastric juices from patients with gastric cancer, ulcer, and atrophic gastritis.
Allopurinol Protects against Ischemia/Reperfusion-Induced Injury in Rat Urinary Bladders.
Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs.
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part I: Quantitation of superoxide dismutase, catalase, glutathione peroxidase and xanthine oxidase.
Brief historical note: the concept of "gonadal dysgenesis".
Conversion of xanthine dehydrogenase to xanthine oxidase as a possible marker for hypoxia in tumours and normal tissues.
Cytokine-mediated xanthine oxidase upregulation in chronic obstructive pulmonary disease's airways.
Design, synthesis, biological evaluation of 3,5-diaryl-4,5-dihydro-1H-pyrazole carbaldehydes as non-purine xanthine oxidase inhibitors: Tracing the anticancer mechanism via xanthine oxidase inhibition.
Determination of oxygen derived free radicals producer (xanthine oxidase) and scavenger (paraoxonase1) enzymes and lipid parameters in different cancer patients.
Dose-dependent regulation of superoxide anion on the proliferation, differentiation, apoptosis and necrosis of human hepatoma cells: the role of intracellular Ca 2+.
Effects of aqueous soybean, mistletoe and red clover extracts on activities of adenosine deaminase and xanthine oxidase enzyme.
Eicosapentaenoic acid and oxypurinol in the treatment of muscle wasting in a mouse model of cancer cachexia.
Flavonoid glycosides isolated from unique legume plant extracts as novel inhibitors of xanthine oxidase.
Glutathione peroxidase, glutathione-S-transferase, catalase, xanthine oxidase, Cu-Zn superoxide dismutase activities, total glutathione, nitric oxide, and malondialdehyde levels in erythrocytes of patients with small cell and non-small cell lung cancer.
IFN-? regulates xanthine oxidase-mediated iNOS-independent oxidative stress in maneb- and paraquat-treated rat polymorphonuclear leukocytes.
Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia.
Inhibitory effect of curcumin on xanthine dehydrogenase/oxidase induced by phorbol-12-myristate-13-acetate in NIH3T3 cells.
Monosodium Urate and Tumor Necrosis Factor-? Increase Apoptosis in Human Chondrocyte Cultures.
Murine epidermal xanthine oxidase activity: correlation with degree of hyperplasia induced by tumor promoters.
Pro-Oxidant Enzymes, Redox Balance and Oxidative Damage to Proteins, Lipids and DNA in Colorectal Cancer Tissue. Is Oxidative Stress Dependent on Tumour Budding and Inflammatory Infiltration?
Reductive activation of doxorubicin by xanthine dehydrogenase from EMT6 mouse mammary carcinoma tumors.
Serum level of Xanthine oxidase, Uric Acid, and NADPH oxidase1 in Stage I of Multiple Myeloma.
Superoxide radical potentiates invasive capacity of rat ascites hepatoma cells in vitro.
Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth.
The xanthine oxidase inhibitor oxypurinol reduces cancer cachexia-induced cardiomyopathy.
Transforming growth factor-betas block cytokine induction of catalase and xanthine oxidase mRNA levels in cultured rat cardiac cells.
Tumor necrosis factor-alpha alters response of lung cancer cells to oxidative stress.
Tumor-targeting chemotherapy by a xanthine oxidase-polymer conjugate that generates oxygen-free radicals in tumor tissue.
X-linked tumor suppressor genes act as presumed contributors in the sex chromosome- autosome crosstalk in cancers.
Xanthine oxidase inhibitory activity and antihyperuricemic effect of Moringa oleifera Lam. leaf hydrolysate rich in phenolics and peptides.
Xanthine oxidase released from reperfused hind limbs mediate kupffer cell activation, neutrophil sequestration, and hepatic oxidative stress in rats subjected to tourniquet shock.
Xanthogranulomatous osteomyelitis of the humerus in a pediatric patient with Alagille syndrome: a case report and literature review.
[Effects of psychological stress on xanthine oxidase expression, activity and related markers in adipose tissue of mice].
Nephritis
Oxidant stress in hyperlipidemia-induced renal damage.
Nephrolithiasis
Inappropriate prescription of allopurinol and febuxostat and risk of adverse events in the elderly: results from the REPOSI registry.
Neurofibromatoses
[Juvenile chronic myelocytic leukemia associated with neurofibromatosis and 45, XO karyotype (author's transl)]
Neurologic Manifestations
Xanthine oxidase-derived hydrogen peroxide contributes to ischemia reperfusion-induced edema in gerbil brains.
Non-alcoholic Fatty Liver Disease
Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis.
Xanthine oxidase inhibition attenuates insulin resistance and diet-induced steatohepatitis in mice.
Noonan Syndrome
Brief historical note: the concept of "gonadal dysgenesis".
Obesity
Body mass index is independently associated with xanthine oxidase activity in overweight/obese population.
Inappropriate prescription of allopurinol and febuxostat and risk of adverse events in the elderly: results from the REPOSI registry.
Inhibitory effects of various solvent extracts from Rhamnus frangula leaves on some inflammatory and metabolic enzymes.
Weight Loss Mediated Reduction in Xanthine Oxidase Activity and Uric Acid Clearance in Adolescents with Severe Obesity.
Xanthine oxidase and cardiovascular risk in obese children.
Oophoritis
Premature gonadal failure in female dogs and cats.
Osteoarthritis
In vivo effect of celecoxib and tenoxicam on oxidant/ anti-oxidant status of patients with knee osteoarthritis.
Osteomyelitis
Xanthogranulomatous osteomyelitis of the humerus in a pediatric patient with Alagille syndrome: a case report and literature review.
Otitis Media with Effusion
Protective effect of melatonin on experimental otitis media with effusion in guinea pigs.
Overweight
Xanthine oxidase activation in mild gestational hypertension.
Pancreatitis
The mechanism of conversion of xanthine dehydrogenase to xanthine oxidase in acute pancreatitis in the canine isolated pancreas preparation.
The role of acetaldehyde in the pathogenesis of acute alcoholic pancreatitis.
Pancreatitis, Alcoholic
The role of acetaldehyde in the pathogenesis of acute alcoholic pancreatitis.
Papilloma
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part I: Quantitation of superoxide dismutase, catalase, glutathione peroxidase and xanthine oxidase.
Persistent Infection
Hepatic xanthine oxidase activity and purine nucleosides levels as physiological mediators to analyze a subcutaneous treatment with (PhSe)2 in mice infected by Toxoplasma gondii.
Pituitary Neoplasms
[TURNER'S SYNDROME WITH PITUITARY ADENOMA AND XO KARYOTYPE.]
Pre-Eclampsia
Is Xanthine Oxidase, a Marker in Pre-eclampsia? A Case-Control Study.
Maternal and fetal plasma adenosine deaminase, xanthine oxidase and malondialdehyde levels in pre-eclampsia.
Plasma xanthine oxidase, superoxide dismutase and glutathione peroxidase activities and uric acid levels in severe and mild pre-eclampsia.
Prostatic Neoplasms
Anti-gout agent allopurinol exerts cytotoxicity to human hormone-refractory prostate cancer cells in combination with tumor necrosis factor-related apoptosis-inducing ligand.
Proteinuria
Modulation of proteinuria and renal xanthine oxidase activity by dietary proteins in acute adriamycin nephrosis in rats: lack of correlation with intra- and extracellular amino acids.
Potential sources of oxidative stress that induce postexercise proteinuria in rats.
Renal purine efflux and xanthine oxidase activity during experimental nephrosis in rats: difference between puromycin aminonucleoside and adriamycin nephrosis.
Uric acid promotes vascular stiffness, maladaptive inflammatory responses and proteinuria in western diet fed mice.
Pseudopseudohypoparathyroidism
Limb anomalies in chromosomal aberrations.
Pulmonary Disease, Chronic Obstructive
Cytokine-mediated xanthine oxidase upregulation in chronic obstructive pulmonary disease's airways.
Implication of xanthine oxidase in muscle oxidative stress in COPD patients.
Xanthine oxidase inhibition reduces reactive nitrogen species production in COPD airways.
Xanthine oxidase is involved in exercise-induced oxidative stress in chronic obstructive pulmonary disease.
Pulmonary Edema
Role of xanthine oxidase and reactive oxygen intermediates in LPS- and TNF-induced pulmonary edema.
Xanthine oxidase-derived oxygen radicals induce pulmonary edema via direct endothelial cell injury.
[Effect of the products released from the activated human neutrophils and endotoxin on bovine pulmonary endothelial cells]
Renal Insufficiency
Circulating purine compounds, uric acid, and xanthine oxidase/dehydrogenase relationship in essential hypertension and end stage renal disease.
Differential in vitro inhibition studies of some cerium vanadate derivatives on xanthine oxidase.
The renal phenotype of allopurinol-treated HPRT-deficient mouse.
Renal Insufficiency, Chronic
An evidence-based review on urate-lowering treatments: implications for optimal treatment of chronic hyperuricemia.
Efficacy of xanthine oxidase inhibitor for chronic kidney disease patients with hyperuricemia.
Use of xanthine oxidase inhibitor febuxostat inhibits renal interstitial inflammation and fibrosis in unilateral ureteral obstructive nephropathy.
Reperfusion Injury
4-Amino-6-hydroxypyrazolo [3,4-d]pyrimidine (AHPP) conjugated PEG micelles: water soluble polymeric xanthine oxidase inhibitor.
A reappraisal of xanthine dehydrogenase and oxidase in hypoxic reperfusion injury: the role of NADH as an electron donor.
Allopurinol enhances the contractile response to dobutamine and exercise in dogs with pacing-induced heart failure.
Comparison of warm and cold ischemia of the canine small intestine.
Effects of the acetylene compound from Atractylodes rhizome on experimental gastric ulcers induced by active oxygen species.
Existence and participation of xanthine oxidase in reperfusion injury of ischemic rabbit myocardium.
Hyperoxia and xanthine dehydrogenase/oxidase activities in rat lung and heart.
Mechanisms of gastrointestinal ischemia-reperfusion injury and potential therapeutic interventions: a review and its implications in the horse.
PentaLyte decreases lung injury after aortic occlusion-reperfusion.
The hypoxanthine-xanthine oxidase axis is not involved in the initial phase of clinical transplantation-related ischemia-reperfusion injury.
The potential role for xanthine oxidase inhibition in major intra-abdominal surgery.
Trolox is more successful than allopurinol to reduce degenerative effects of testicular ischemia/reperfusion injury in rats.
Xanthine oxidase converts nitric oxide to nitroxyl that inactivates the enzyme.
Xanthine oxidase formation during experimental ischemia of the equine small intestine.
Xanthine oxidase mediates elastase-induced injury to isolated lungs and endothelium.
Xanthine oxidase: its role in the no-reflow phenomenon.
[Role of active oxygen species and lipid peroxidation in liver injury induced by ischemia-reperfusion]
[The role of xanthine dehydrogenase (xanthine oxidase) in ischemia-reperfusion injury in rat kidney]
Respiratory Distress Syndrome
Acute and chronic effects of xanthine oxidase on lung thorax-compliance in guinea pigs.
Sarcoma
Xanthogranulomatous osteomyelitis of the humerus in a pediatric patient with Alagille syndrome: a case report and literature review.
Sarcopenia
Evaluation of Oxidative Stress Parameters and Antioxidant Status in Plasma and Erythrocytes of Elderly Diabetic Patients with Sarcopenia.
Seminoma
Seminoma in a 12-year-old male with 46 XY/45 XO karyotype.
Sepsis
Alterations in antioxidant status during neonatal sepsis.
The impact of xanthine oxidase (XO) on hemolytic diseases.
Xanthine oxidase activity in patients with sepsis.
Sex Chromosome Aberrations
Human blastocysts of normal and abnormal karyotypes display distinct transcriptome profiles.
Mental illness and sex chromosome aberration: renewed interest in light of a current survey.
[Mixed gonadal dysgenesis]
Situs Inversus
Genotoxic assessment of small mammals at an illegal dumpsite at the aomori-iwate prefectural boundary.
Spinal Cord Injuries
Xanthine oxidase in experimental spinal cord injury.
Staphylococcal Infections
A Rare Case Report on Xanthogranulomatous Osteomyelitis of Hip Mimicking Tuberculosis and Review of Literature.
steryl-sulfatase deficiency
Dosage of the Sts gene in the mouse.
Stomach Diseases
Myeloperoxidase, xanthine oxidase and superoxide dismutase in the gastric mucosa of helicobacter pylori positive and negative pediatric patients.
Stomach Ulcer
Upregulation of xanthine oxidase by tobacco smoke condensate in pulmonary endothelial cells.
Stroke
Synthesis and characterization of CAPE derivatives as xanthine oxidase inhibitors with radical scavenging properties.
Subarachnoid Hemorrhage
Production of uric acid in cerebrospinal fluid after subarachnoid hemorrhage in dogs: investigation of the possible role of xanthine oxidase in chronic vasospasm.
Teratozoospermia
[Sperm sex chromosome analysis and preimplantation genetic diagnosis of patients with sex chromosome anomalies]
Trisomy 13 Syndrome
Sensitivity of multiple first trimester sonomarkers in fetal aneuploidy detection.
Trisomy 18 Syndrome
Antenatal diagnosis of coarctation of the aorta: a multicenter experience.
Sensitivity of multiple first trimester sonomarkers in fetal aneuploidy detection.
Turner Syndrome
Androgens, estrogens, and the ultimate height in XO gonadal dysgenesis.
Aortic dilatation resulting in chronic aortic regurgitation and complicated by aortic dissection in a patient with Turner's syndrome.
Blood typing invalidates alleged evidence of fertility of XO mare.
Brief historical note: the concept of "gonadal dysgenesis".
Characteristic cardiovascular anomalies of XO Turner syndrome, XX and XY phenotype and XO-XX Turner mosaic.
Comparative cephalometric analysis in patients with X-chromosome aneuploidy.
Crohn's disease in Turner's syndrome with X-chromosomal mosaicism of 45 XO and 47 XXX.
Cytogenetic and molecular findings in patients with Turner's syndrome stigmata.
Defects in the first wave of folliculogenesis in mouse XO ovaries.
Detection of chromosomal abnormalities in the dysmorphic fetus using fluorescence in situ hybridization: evaluation for monosomy X genotype.
Does growth hormone treatment of patients with Turner's syndrome cause an abnormal body shape?
Effects on fear reactivity in XO mice are due to haploinsufficiency of a non-PAR X gene: implications for emotional function in Turner's syndrome.
Embryonal carcinoma arising in Turner's syndrome.
Endarteritis of the aortic arch in Turner's syndrome with cystic degeneration of the aorta.
Generation of an induced pluripotent stem cell line from chorionic villi of a Turner syndrome spontaneous abortion.
Genotype, phenotype, and karyotype correlation in the XO mouse model of Turner Syndrome.
Growth deficiency dysmorphic syndromes.
Growth of Argentinian girls with Turner syndrome.
Hyperandrogenism in a girl with Turner syndrome: A case report.
Hypertensive Cerebral Hemorrhage in a Patient with Turner Syndrome Caused by Deletion in the Short Arm of the X Chromosome.
Hypoplastic left heart syndrome with premature closure of foramen ovale: report of an unusual type of totally anomalous pulmonary venous return.
Infertility and multiple urogenital abnormalities in a male with mosaic 46,XY/45,XO/47,XXY karyotype and mixed phenotype.
Influence of oestrogen in high and low doses on plasma steroid concentrations in girls with tall stature and Turner syndrome.
Letter: Asynchronous growth of scalp hair in XO Turner syndrome.
Molecular detection of XO - Turner syndrome.
Mosaicism in Turner's syndrome reflects the lethality of XO.
No evidence for chromosomal mosaicism in multiple tissues of 10 patients with 45, XO Turner syndrome.
Premature ovarian insufficiency in the XO female mouse on the C57BL/6J genetic background.
Prepubertal periodontitis: a genetic analysis.
Radioimmunoassay of progesterone in saliva.
Radiological and clinical analysis of Madelung's deformity in children.
Sex differences in brain expression of X- and Y-linked genes.
Sex-linked ichthyosis in XO gonadal dysgenesis.
Sexually dimorphic expression of Usp9x is related to sex chromosome complement in adult mouse brain.
Source of single X in XO Turner syndrome: a comment.
Studying early lethality of 45,XO (Turner's syndrome) embryos using human embryonic stem cells.
The D triisomy syndrome and XO gonadal dysgenesis in two sisters.
The mouse as a model of fundamental concepts related to Turner syndrome.
The position of the external ear in Turner's syndrome.
Three novel mutations causing complete T(4)-binding globulin deficiency.
Toxicity and outcome of intensive chemotherapy for acute lymphoblastic leukemia complicated with Turner's syndrome.
Transcriptional changes in response to X chromosome dosage in the mouse: implications for X inactivation and the molecular basis of Turner Syndrome.
Tunnel subaortic stenosis in XO Turner's syndrome.
Turner's syndrome and carbohydrate metabolism. II. Parotid salivary insulin concentration in normal subjects and in patients with gonadal dysgenesis.
Turner's syndrome occurring with Horner's syndrome. Seen with coarctation of the aorta and aortic aneurysm.
Typical Turner's syndrome with 45 XO karyotype and normal menstruation. Cytogenetic and histological findings.
Virilization in Turner syndrome.
X-chromosome inactivation may explain the difference in viability of XO humans and mice.
X-chromosome monosomy in the myelin-deficient rat mutant.
[45, XO Turner's syndrome associated with menarche and diabetes mellitus]
[A case of 45 XO Turner's syndrome. Cytohormonal interpretation of the vaginal smear in the test of ovarian stimulation with chorionic gonadotropin]
[Chronic type A aortic dissection associated with Turner syndrome; report of a case].
[Clinical difference between XO Turner's syndrome and 45,X-46,XX mosaicism]
[COMMENTS ON THE XO TYPE OF TURNER'S SYNDROME.]
[DISCUSSION OF THE PATERNAL ORIGIN OF THE X CHROMOSOME FROM A TURNER SYNDROME, XO, PROTANOPE AND XG (A-).]
[Discussion of the paternal origin of the X of a protanopic and Xg(a--) XO Turner syndrome. New numerical estimation]
[Echographic diagnosis of cystic hygroma. Apropos of a case]
[Effects of weakly androgenic anabolic steroids on growth in Turner's syndrome]
[FAMILIAL TURNER'S SYNDROME. STUDY OF 2 FAMILIES WITH XO AND XX KARYOTYPES.]
[Feedback--regulation mechanisms using a multiple graded mestranol-norethisterone sequential preparation in XO Turner's syndrome]
[Height in Turner's syndrome: correlation with parents' height]
[Hygroma colli in the ultrasound image as an early indication of fetal Ullrich-Turner syndrome]
[Significance of dermatoglyphics and palmar furrows for genetic and clinical problem formation in gynecology and obstetrics]
[Stimulation test of the adenohypophysis with arginine, gonadotropin-releasing hormone (GRH), and thyrotropin-releasing hormone (TRH) in 45, XO patients with Turner's syndrome (author's transl)]
[Turner's syndrome with karyotype XO associated with the Debré-Fibiger syndrome]
[TURNER'S SYNDROME WITH PITUITARY ADENOMA AND XO KARYOTYPE.]
[XO type of Turner's syndrome associated with coarctation of aorta---case report (author's transl)]
[XY, XO, XX mosaicism with Turner's syndrome]
Urinary Bladder Neoplasms
Adenosine deaminase and xanthine oxidase activities in bladder washing fluid from patients with bladder cancer: a preliminary study.
Levels of certain tumor markers as differential factors between bilharzial and non-biharzial bladder cancer among Egyptian patients.
Urinary Tract Infections
Urine xanthine oxidase activity in urinary tract infection.
Urogenital Abnormalities
Infertility and multiple urogenital abnormalities in a male with mosaic 46,XY/45,XO/47,XXY karyotype and mixed phenotype.
Vascular Diseases
Oxypurinol improves coronary and peripheral endothelial function in patients with coronary artery disease.
Vascular Ring
Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits.
Superoxide radical-mediated endothelial injury and vasoconstriction of rat thoracic aortic rings.
Vascular System Injuries
Dietary inhibition of xanthine oxidase attenuates radiation-induced endothelial dysfunction in rat aorta.
Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol.
Vasospasm, Intracranial
Production of uric acid in cerebrospinal fluid after subarachnoid hemorrhage in dogs: investigation of the possible role of xanthine oxidase in chronic vasospasm.
Virus Diseases
Dependence on O2- generation by xanthine oxidase of pathogenesis of influenza virus infection in mice.
Xanthine Oxidase-Induced Inflammatory Responses in Respiratory Epithelial Cells: A Review in Immunopathology of COVID-19.
Vitiligo
Oxidant-antioxidant enzymes and lipid peroxidation in generalized vitiligo.
Presence of epidermal allantoin further supports oxidative stress in vitiligo.
Whooping Cough
Biphasic alterations in cardiac beta-adrenoceptor signal transduction mechanism due to oxyradicals.
xanthine oxidase deficiency
Molybdenum: an essential trace element.
XYY Karyotype
Detection of sex chromosome aneuploidies using quantitative fluorescent PCR in the Hungarian population.