Information on EC 1.15.1.1 - superoxide dismutase

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The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota

EC NUMBER
COMMENTARY hide
1.15.1.1
-
RECOMMENDED NAME
GeneOntology No.
superoxide dismutase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 superoxide + 2 H+ = O2 + H2O2
show the reaction diagram
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
-
-
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redox reaction
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reduction
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
ethylene biosynthesis III (microbes)
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non-pathway related
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reactive oxygen species degradation
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superoxide radicals degradation
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SYSTEMATIC NAME
IUBMB Comments
superoxide:superoxide oxidoreductase
A metalloprotein; also known as erythrocuprein, hemocuprein or cytocuprein. Enzymes from most eukaryotes contain both copper and zinc; those from mitochondria and most prokaryotes contain manganese or iron.
CAS REGISTRY NUMBER
COMMENTARY hide
9054-89-1
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
Mn-SOD
-
-
Manually annotated by BRENDA team
Mn-SOD
-
-
Manually annotated by BRENDA team
; isolated from a terrestrial acidic hot spring, Kamchatka peninsula, Russia, gene ASAC_0498
UniProt
Manually annotated by BRENDA team
strain LFI1238, gene sodB
SwissProt
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
Amphiprora kufferathii
-
-
-
Manually annotated by BRENDA team
Cu,Zn-SOD; Peking duck
-
-
Manually annotated by BRENDA team
Anas platyrhynchos domestica CuZn-SOD
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
three types of Cu/ZNSOD
-
-
Manually annotated by BRENDA team
5 isozymes: SOD-II, SOD-III, SOD-IV, and SOD-V are Cu,Zn-SODs, SOD-I is a Mn-SOD
-
-
Manually annotated by BRENDA team
Fe-SOD
-
-
Manually annotated by BRENDA team
Fe-SOD
-
-
Manually annotated by BRENDA team
3 isozymes: Mn-SOD, Cu,Zn-SOD I and II
-
-
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
Cu,Zn-SOD
SwissProt
Manually annotated by BRENDA team
Cu,Zn-SOD
SwissProt
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
strain 26
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-
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
Mn-SOD
-
-
Manually annotated by BRENDA team
Mn-SOD
-
-
Manually annotated by BRENDA team
IFO 3329; Mn-SOD
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-
Manually annotated by BRENDA team
Mn-SOD
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-
Manually annotated by BRENDA team
collected from soil and water samples from hot springs in Mae Hong Son Province of Thailand, gene sodA
UniProt
Manually annotated by BRENDA team
collected from soil and water samples from hot springs in Mae Hong Son Province of Thailand, gene sodA
UniProt
Manually annotated by BRENDA team
gene BbSod1
UniProt
Manually annotated by BRENDA team
gene BbSod1
UniProt
Manually annotated by BRENDA team
Bos taurus CuZn-SOD
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
Cu,Zn-SOD; var. bullata sub var. gemmifera
-
-
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
Fe-SOD
-
-
Manually annotated by BRENDA team
; strain K56-2
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-
Manually annotated by BRENDA team
strain K56-2
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-
Manually annotated by BRENDA team
isolated from a melioidosis patient in Korea
UniProt
Manually annotated by BRENDA team
isolated from a melioidosis patient in Korea
UniProt
Manually annotated by BRENDA team
SOD-3 gene, Mn-SOD
Uniprot
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
strain CB15
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-
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
-
UniProt
Manually annotated by BRENDA team
strain CT2
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-
Manually annotated by BRENDA team
gene Ctsod
UniProt
Manually annotated by BRENDA team
Fe-SOD
Uniprot
Manually annotated by BRENDA team
Fe-SOD
Uniprot
Manually annotated by BRENDA team
cv. sugar baby
Uniprot
Manually annotated by BRENDA team
Cu,Zn-SOD: SOD-II
-
-
Manually annotated by BRENDA team
Cu,Zn-SOD
Uniprot
Manually annotated by BRENDA team
Citrus limon CuZn-SOD
Cu,Zn-SOD
Uniprot
Manually annotated by BRENDA team
gene CuZnSOD
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-
Manually annotated by BRENDA team
3 isozymes; Fe-SOD
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-
Manually annotated by BRENDA team
Fe-SOD
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-
Manually annotated by BRENDA team
isoform SOD2
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-
Manually annotated by BRENDA team
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-
Manually annotated by BRENDA team
ATCC 31317
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-
Manually annotated by BRENDA team
Mn-SOD, and 2 isozymes of Cu,Zn-SOD
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-
Manually annotated by BRENDA team
strain AB
UniProt
Manually annotated by BRENDA team
a grass specie adapted to the extreme climate of the Maritime Antarctic
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Manually annotated by BRENDA team
Fe-SOD
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-
Manually annotated by BRENDA team
Fe-SOD
-
-
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
CCM 2867
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Manually annotated by BRENDA team
CCM 2867
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Manually annotated by BRENDA team
strain IFO 3317
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Manually annotated by BRENDA team
strain IFO 3317
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Manually annotated by BRENDA team
Fe-SOD
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-
Manually annotated by BRENDA team
Mn-SOD
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-
Manually annotated by BRENDA team
collected from a tepid spring, 41C, pH 7.9, in Oguni-tyo, Kumamoto, Japan, gene sodA
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Manually annotated by BRENDA team
collected from a tepid spring, 41C, pH 7.9, in Oguni-tyo, Kumamoto, Japan, gene sodA
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Manually annotated by BRENDA team
A-101, A-217, A-364
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Manually annotated by BRENDA team
several FeSOD and MnSOD isozymes
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-
Manually annotated by BRENDA team
Gallus gallus CuZn-SOD
Cu,Zn-SOD
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-
Manually annotated by BRENDA team
Geobacillus sp.
gene sod
UniProt
Manually annotated by BRENDA team
gene sod
UniProt
Manually annotated by BRENDA team
IFO 3268, Mn-SOD
-
-
Manually annotated by BRENDA team
isoform MnSOD
SwissProt
Manually annotated by BRENDA team
strain NRL, enzyme is oxygen-inducible
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-
Manually annotated by BRENDA team
CCM 2833; Fe-SOD and Mn-SOD
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-
Manually annotated by BRENDA team
CCM 2833
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-
Manually annotated by BRENDA team
contains a single type A isozyme Fe-SOD encoded by gene sodB
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-
Manually annotated by BRENDA team
Mn-SOD
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-
Manually annotated by BRENDA team
Mn-SOD
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-
Manually annotated by BRENDA team
Homo sapiens Mn-SOD
Mn-SOD
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-
Manually annotated by BRENDA team
strain 103, isozymes Cu/Zn-SOD and Mn-SOD
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Manually annotated by BRENDA team
strain 103, isozymes Cu/Zn-SOD and Mn-SOD
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-
Manually annotated by BRENDA team
fall webworm, gene sod
UniProt
Manually annotated by BRENDA team
SOD1; strain L3, gene KmSod1
UniProt
Manually annotated by BRENDA team
strain NBIMCC 1984
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-
Manually annotated by BRENDA team
-
UniProt
Manually annotated by BRENDA team
-
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-
Manually annotated by BRENDA team
Cu,Zn-SOD
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-
Manually annotated by BRENDA team
Lens culinaris CuZn-SOD
Cu,Zn-SOD
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-
Manually annotated by BRENDA team
Fe-SOD
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-
Manually annotated by BRENDA team
gene sod3
UniProt
Manually annotated by BRENDA team
gene sod3
UniProt
Manually annotated by BRENDA team
expression in potato
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-
Manually annotated by BRENDA team
Cu,Zn-SOD; var. diptera
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Manually annotated by BRENDA team
Cu,Zn-SOD
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-
Manually annotated by BRENDA team
Marinomonas sp.
strain NJ522
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Manually annotated by BRENDA team
strain NJ522
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Manually annotated by BRENDA team
-
UniProt
Manually annotated by BRENDA team
Cu/Zn superoxide dismutase
SwissProt
Manually annotated by BRENDA team
3 isozymes
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-
Manually annotated by BRENDA team
Fe-SOD
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-
Manually annotated by BRENDA team
strain AZ, strict anaerobic methanogenic archaeon
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-
Manually annotated by BRENDA team
strain AZ, strict anaerobic methanogenic archaeon
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Manually annotated by BRENDA team
Methanothermobacter thermautotrophicum
Fe-SOD, but features are similar to Mn-SOD
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Manually annotated by BRENDA team
strain SK1, DSM 8269
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Manually annotated by BRENDA team
strain SK1, DSM 8269
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-
Manually annotated by BRENDA team
NCMB 559
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Manually annotated by BRENDA team
NCMB 559
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-
Manually annotated by BRENDA team
scallop Mn-superoxide dismutase
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-
Manually annotated by BRENDA team
gene sodA
UniProt
Manually annotated by BRENDA team
gene sodA
UniProt
Manually annotated by BRENDA team
CCM 2873
-
-
Manually annotated by BRENDA team
CCM 2873
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-
Manually annotated by BRENDA team
adult, 3 isoforms
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-
Manually annotated by BRENDA team
recombinant enzyme
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-
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
Mn-SOD
-
-
Manually annotated by BRENDA team
nectarin I with Mn-SOD activity
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-
Manually annotated by BRENDA team
isozyme Cu,Zn-SODIII
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-
Manually annotated by BRENDA team
no activity in Colwellia sp.
strain MH2
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-
Manually annotated by BRENDA team
no activity in Colwellia sp. MH3
strain MH2
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-
Manually annotated by BRENDA team
no activity in Giardia intestinalis
-
-
-
Manually annotated by BRENDA team
strain GUH-2
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-
Manually annotated by BRENDA team
formerly Anabaena sp., strain PCC 7120
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-
Manually annotated by BRENDA team
Fe-SOD; sub spec. macrophyllum
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-
Manually annotated by BRENDA team
Nuphar lutea Fe-SOD
Fe-SOD
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
Mn-SOD
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-
Manually annotated by BRENDA team
intracellular parasite of the Eastern oyster crassostrea virginica
-
-
Manually annotated by BRENDA team
Fe-SOD; subsp. piscicida, formerly Pasteurelle piscicida
SwissProt
Manually annotated by BRENDA team
Fe-SOD
SwissProt
Manually annotated by BRENDA team
strain ATCC25521
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-
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
isolated from Euphorbia characias, isozymes SODI, SODII
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-
Manually annotated by BRENDA team
five isozymes of MnSOD
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-
Manually annotated by BRENDA team
expression of three enzyme isoforms
-
-
Manually annotated by BRENDA team
Pibocella sp.
strain MH3
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-
Manually annotated by BRENDA team
Pibocella sp. MH3
strain MH3
-
-
Manually annotated by BRENDA team
from from the pearl farm in Tuticurin, south coast of India
UniProt
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
4 isozymes: SOD-I, SOD-II, SOD-III, SOD-IV
-
-
Manually annotated by BRENDA team
Mn-SOD
-
-
Manually annotated by BRENDA team
NCMB 561
-
-
Manually annotated by BRENDA team
NCMB 561
-
-
Manually annotated by BRENDA team
Mn-SOD
-
-
Manually annotated by BRENDA team
Mn-SOD
-
-
Manually annotated by BRENDA team
structural intermediate between Mn-SOD and Fe-SOD
-
-
Manually annotated by BRENDA team
gene sodA
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-
Manually annotated by BRENDA team
strain PAO1
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-
Manually annotated by BRENDA team
Mn-SOD; strain DSM 1083
-
-
Manually annotated by BRENDA team
Mn-SOD
-
-
Manually annotated by BRENDA team
Fe-SOD
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
Radix lethospermi
-
-
-
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
Mn-SOD
-
-
Manually annotated by BRENDA team
male rats
-
-
Manually annotated by BRENDA team
Mn-SOD
-
-
Manually annotated by BRENDA team
Rhodothermus sp.
strain XMH10
-
-
Manually annotated by BRENDA team
strain XMH10
-
-
Manually annotated by BRENDA team
Cu,Zn-SOD
-
-
Manually annotated by BRENDA team
Mn-SOD
-
-
Manually annotated by BRENDA team
a human pathogenic fungus, strain 90.4595, gene sodC
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-
Manually annotated by BRENDA team
strain Rm5000; structural intermediate between Mn-SOD and Fe-SOD
-
-
Manually annotated by BRENDA team
strain Rm5000
-
-
Manually annotated by BRENDA team
Fe-SOD
-
-
Manually annotated by BRENDA team
collected from Qinglangang Mangrove Reserve, Wenchang, Hainan, China
-
-
Manually annotated by BRENDA team
Mn-SOD
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
Sulfitobacter sp.
strain MH1
-
-
Manually annotated by BRENDA team
Sulfitobacter sp. MH1
strain MH1
-
-
Manually annotated by BRENDA team
strain Gtheta
-
-
Manually annotated by BRENDA team
strain MT-4, ATCC 49255
-
-
Manually annotated by BRENDA team
gene sodA
UniProt
Manually annotated by BRENDA team
MnSOD
SwissProt
Manually annotated by BRENDA team
strain P134
-
-
Manually annotated by BRENDA team
strain P134
-
-
Manually annotated by BRENDA team
Fe-SOD
-
-
Manually annotated by BRENDA team
Fe-SOD
-
-
Manually annotated by BRENDA team
Mn-SOD
-
-
Manually annotated by BRENDA team
Mn-SOD
-
-
Manually annotated by BRENDA team
-
UniProt
Manually annotated by BRENDA team
Thermus filiformis ATCC 43280
-
UniProt
Manually annotated by BRENDA team
Mn-SOD
-
-
Manually annotated by BRENDA team
Cu/ZnSOD
SwissProt
Manually annotated by BRENDA team
isolated from a hot spring sample
-
-
Manually annotated by BRENDA team
Mn-SOD
-
-
Manually annotated by BRENDA team
RSS-30 chemotype
UniProt
Manually annotated by BRENDA team
Cu,Zn-SOD: 3 isozymes AA, AB, BB
-
-
Manually annotated by BRENDA team
Zea mays SOD-I
SOD-I
-
-
Manually annotated by BRENDA team
Zea mays SOD-III
SOD-III
-
-
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
malfunction
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MnSOD ala16val polymorphism is associated with various diseases including breast cancer
physiological function
additional information
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2 O2.- + 2 H+
O2 + H2O2
show the reaction diagram
2 O2.- + 2 H+ +
O2 + H2O2
show the reaction diagram
2 superoxide + 2 H+
O2 + H2O2
show the reaction diagram
nitro blue tetrazolium + ?
?
show the reaction diagram
Nitroblue Tetrazolium + ?
?
show the reaction diagram
O2- + H+
O2 + H2O2
show the reaction diagram
O2.- + 4-[3-(4-iodophenyl)-2-(4-nitrophenyl)-2H-5-tetrazolio]-1,3-benzene disulfonate
?
show the reaction diagram
i.e. WST-1, activity assay detection method
-
-
?
O2.- + H+
O2 + H2O2
show the reaction diagram
pyrogallol + ?
?
show the reaction diagram
riboflavin + ?
?
show the reaction diagram
additional information
?
-