Information on EC 1.14.99.34 - monoprenyl isoflavone epoxidase

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The expected taxonomic range for this enzyme is: Botryotinia fuckeliana

EC NUMBER
COMMENTARY
1.14.99.34
-
RECOMMENDED NAME
GeneOntology No.
monoprenyl isoflavone epoxidase
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
7-O-methylluteone + NADPH + H+ + O2 = dihydrofurano derivatives + NADP+ + H2O
show the reaction diagram
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
oxidation
-
-
-
-
redox reaction
-
-
-
-
reduction
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-
-
-
SYSTEMATIC NAME
IUBMB Comments
7-O-methylluteone,NADPH:O2 oxidoreductase
A flavoprotein (FAD) with high specificity for monoprenyl isoflavone. The product of the prenyl epoxidation reaction contains an oxygen atom derived from O2, but not from H2O. It is slowly and nonenzymically converted into the corresponding dihydrofurano derivative. The enzyme in the fungus Botrytis cinerea is induced by the substrate analogue, 6-prenylnaringenin.
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
epoxidase, monoprenyl isoflavone
-
-
-
-
monoprenyl isoflavone monooxygenase
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-
-
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CAS REGISTRY NUMBER
COMMENTARY
198496-86-5
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                      
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2'-hydroxylupalbigenin + NADPH + O2
?
show the reaction diagram
-
-
-
-
?
2,3-dihydrokievitone + NADPH + O2
?
show the reaction diagram
-
-
-
-
?
7-O-methyl-2,3-dehydrokievitone + NADPH + O2
?
show the reaction diagram
-
-
-
-
?
7-O-methylluteone + NADH + O2
dihydrofurano derivative of 7-O-methylluteone + NADP+ + H2O
show the reaction diagram
-
-
-
?
7-O-methylluteone + NADPH + O2
dihydrofurano derivative of 7-O-methylluteone + NADP+ + H2O
show the reaction diagram
-
-
-
?
7-O-methylluteone + NADPH + O2
dihydrofurano derivatives + NADP+ + H2O
show the reaction diagram
-
key enzyme in metabolism of prenylated flavonoids. Enzyme is induced by the substrate analogue 6-prenylnaringenin
-
?
licoisoflavone A + NADPH + O2
?
show the reaction diagram
-
-
-
-
?
luteone + NADPH + O2
?
show the reaction diagram
-
-
-
-
?
wighteone + NADPH + O2
?
show the reaction diagram
-
-
-
-
?
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
7-O-methylluteone + NADPH + O2
dihydrofurano derivatives + NADP+ + H2O
show the reaction diagram
-
key enzyme in metabolism of prenylated flavonoids. Enzyme is induced by the substrate analogue 6-prenylnaringenin
-
?
COFACTOR
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
IMAGE
FAD
-
required for maximal activity
SOURCE TISSUE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
SOURCE