Information on EC 1.14.99.34 - monoprenyl isoflavone epoxidase

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The expected taxonomic range for this enzyme is: Botrytis cinerea

EC NUMBER
COMMENTARY hide
1.14.99.34
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RECOMMENDED NAME
GeneOntology No.
monoprenyl isoflavone epoxidase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
7-O-methylluteone + NADPH + H+ + O2 = dihydrofurano derivatives + NADP+ + H2O
show the reaction diagram
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
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redox reaction
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-
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reduction
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SYSTEMATIC NAME
IUBMB Comments
7-O-methylluteone,NADPH:O2 oxidoreductase
A flavoprotein (FAD) with high specificity for monoprenyl isoflavone. The product of the prenyl epoxidation reaction contains an oxygen atom derived from O2, but not from H2O. It is slowly and non-enzymically converted into the corresponding dihydrofurano derivative. The enzyme in the fungus Botrytis cinerea is induced by the substrate analogue, 6-prenylnaringenin.
CAS REGISTRY NUMBER
COMMENTARY hide
198496-86-5
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2'-hydroxylupalbigenin + NADPH + O2
?
show the reaction diagram
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-
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?
2,3-dihydrokievitone + NADPH + O2
?
show the reaction diagram
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-
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?
7-O-methyl-2,3-dehydrokievitone + NADPH + O2
?
show the reaction diagram
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-
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-
?
7-O-methylluteone + NADH + O2
dihydrofurano derivative of 7-O-methylluteone + NAD+ + H2O
show the reaction diagram
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-
-
?
7-O-methylluteone + NADPH + O2
dihydrofurano derivative of 7-O-methylluteone + NADP+ + H2O
show the reaction diagram
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-
-
?
7-O-methylluteone + NADPH + O2
dihydrofurano derivatives + NADP+ + H2O
show the reaction diagram
-
key enzyme in metabolism of prenylated flavonoids. Enzyme is induced by the substrate analogue 6-prenylnaringenin
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?
licoisoflavone A + NADPH + O2
?
show the reaction diagram
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-
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?
luteone + NADPH + O2
?
show the reaction diagram
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-
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?
wighteone + NADPH + O2
?
show the reaction diagram
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?
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
7-O-methylluteone + NADPH + O2
dihydrofurano derivatives + NADP+ + H2O
show the reaction diagram
-
key enzyme in metabolism of prenylated flavonoids. Enzyme is induced by the substrate analogue 6-prenylnaringenin
-
?
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
FAD
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required for maximal activity
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE