Information on EC 1.14.99.11 - estradiol 6beta-monooxygenase

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The expected taxonomic range for this enzyme is: Amniota

EC NUMBER
COMMENTARY
1.14.99.11
-
RECOMMENDED NAME
GeneOntology No.
estradiol 6beta-monooxygenase
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
estradiol-17beta + AH2 + O2 = 6beta-hydroxyestradiol-17beta + A + H2O
show the reaction diagram
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
oxidation
-
-
-
-
redox reaction
-
-
-
-
reduction
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-
-
-
PATHWAY
KEGG Link
MetaCyc Link
Steroid hormone biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
estradiol-17beta,hydrogen-donor:oxygen oxidoreductase (6beta-hydroxylating)
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SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
EC 1.14.1.10
-
-
formerly
-
estradiol 6beta-hydroxylase
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-
-
-
oxygenase, estradiol 6beta-mono-
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-
-
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CAS REGISTRY NUMBER
COMMENTARY
9029-70-3
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ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                      
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
estradiol-17beta + NADPH + O2
6beta-hydroxyestradiol-17beta + NADP+ + H2O
show the reaction diagram
-
-
-
-
-
estradiol-17beta + NADPH + O2
6beta-hydroxyestradiol-17beta + NADP+ + H2O
show the reaction diagram
-
estradiol-17beta i.e. estra-1,3,5(10)-triene-3,17beta-diol
6beta-hydroxyestradiol i.e. 6beta-hydroxyestra-1,3,5(10)-triene-3,17beta-diol
?
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
estradiol-17beta + NADPH + O2
6beta-hydroxyestradiol-17beta + NADP+ + H2O
show the reaction diagram
-
-
-
-
-
estradiol-17beta + NADPH + O2
6beta-hydroxyestradiol-17beta + NADP+ + H2O
show the reaction diagram
-
estradiol-17beta i.e. estra-1,3,5(10)-triene-3,17beta-diol
6beta-hydroxyestradiol i.e. 6beta-hydroxyestra-1,3,5(10)-triene-3,17beta-diol
?
COFACTOR
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
IMAGE
SOURCE TISSUE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
SOURCE
LOCALIZATION
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
Purification/COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE