Information on EC 1.14.19.B9 - cis-DELTA13 desaturase

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The enzyme appears in viruses and cellular organisms

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EC NUMBER
COMMENTARY hide
1.14.19.B9
preliminary BRENDA-supplied EC number
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RECOMMENDED NAME
GeneOntology No.
cis-DELTA13 desaturase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
octadec-9-ynoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+ = (13Z)-octadecen-13-en-9-ynoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
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SYSTEMATIC NAME
IUBMB Comments
9-octadecynoyl-[glycerolipid],ferrocytochrome-b5:oxygen oxidoreductase (13 cis-dehydrogenating)
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
FADX-1A
UniProt
Manually annotated by BRENDA team
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UniProt
Manually annotated by BRENDA team
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
octadec-9-ynoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H+
(13Z)-octadecen-13-en-9-ynoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O
show the reaction diagram
additional information
?
-
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
additional information
?
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
top print hide
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
gene FADX, DNA and amino acid sequence determination and analysis, phylogenetic analysis and tree, quantitative real-time PCR enzyme expression analysis, recombinant expression in Saccharomyces cerevisiae strains ole1 and INVSc1 in microsomes. Santalaceae FADX expressed in yeast has no detectable DELTA12 desaturase activity either acting on native fatty acids or when supplied with exogenous substrates but instead shows cis-DELTA13 desaturation activity on stearolic acid
gene FADX-1A, DNA and amino acid sequence determination and analysis, phylogenetic analysis and tree, quantitative real-time PCR enzyme expression analysis, recombinant expression in Saccharomyces cerevisiae strains ole1 and INVSc1 in microsomes. Santalaceae FADX expressed in yeast has no detectable DELTA12 desaturase activity either acting on native fatty acids or when supplied with exogenous substrates but instead shows cis-DELTA13 desaturation activity on stearolic acid
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LINKS TO OTHER DATABASES (specific for EC-Number 1.14.19.B9)
ExplorEnz
ExPASy
KEGG
MetaCyc
SABIO-RK
NCBI: PubMed, Protein, Nucleotide, Structure, Genome, OMIM
IUBMB Enzyme Nomenclature
PROSITE Database of protein families and domains
SYSTERS
Protein Mutant Database
InterPro (database of protein families, domains and functional sites)