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Reference on EC 1.14.19.22 - acyl-lipid omega-6 desaturase (cytochrome b5)

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Slack, C.R.; Roughan, P.G.; Terpstra, J.
Some properties of a microsomal oleate desaturase from leaves
Biochem. J.
155
71-80
1976
Pisum sativum
Manually annotated by BRENDA team
Demandre, C.; Vigh, L.; Justin, A.M.; Jolliot, A.; Wolf, C.; Mazliak, P.
Effects of the catalytic hydrogenation of microsomal lipids upon four enzyme activities involved in oleic acid desaturation
Plant Sci.
44
13-21
1986
Solanum tuberosum
-
Manually annotated by BRENDA team
Stymne, S.; Appelqvist, L.A.
The biosynthesis of linoleate from oleoyl-CoA via oleoyl-phosphatidylcholine in microsomes of developing safflower seeds
Eur. J. Biochem.
90
223-229
1978
Carthamus tinctorius
Manually annotated by BRENDA team
Umeki, S.; Nozawa, Y.
Thermoadaptive regulation of microsomal desaturase and electron-transport enzyme activities in lipid-manipulated Tetrahymena cells. Extent of unsaturated fatty acid production is dependent on membrane fluidity before temperature down-shift
Biochim. Biophys. Acta
793
123-128
1984
Tetrahymena pyriformis, Tetrahymena pyriformis NT-1
Manually annotated by BRENDA team
Cheesbrough, T.M.
Changes in the enzymes for fatty acid synthesis and desaturation during acclimation of developing soybean seeds to altered growth temperature
Plant Physiol.
90
760-764
1989
Glycine max
Manually annotated by BRENDA team
Murphy, D.J.; Woodrow, I.E.; Latzko, E.; Mukherjee, K.D.
Solubilisation of oleoyl-CoA thioesteras, oleoyl-CoA:phosphatidylcholine acyltransferase and oleoyl phosphatidylcholine desaturase
FEBS Lett.
162
442-446
1983
Pisum sativum
-
Manually annotated by BRENDA team
Citharel, B.; Oursel, A.; Mazliak, P.
Desaturation of oleoyl and linoleoyl residues linked to phospholipids in growing roots of yellow lupin
FEBS Lett.
161
251-256
1983
Lupinus luteus
-
Manually annotated by BRENDA team
Murphy, D.J.; Woodrow, I.E.; Mukherjee, K.D.
Substrate specificities of the enzymes of the oleate desaturase system from photosynthetic tissue
Biochem. J.
225
267-270
1985
Pisum sativum
Manually annotated by BRENDA team
Browse, J.; Slack, C.R.
The effects of temperature and oxygen on the rates of fatty acid synthesis and oleate desaturation in seaflower (Carthamus tinctorius) seed
Biochim. Biophys. Acta
753
145-152
1983
Carthamus tinctorius
-
Manually annotated by BRENDA team
Wilson, A.C.; Adams, W.C.; Miller, R.W.
Lipid involvement in oleoyl CoA desaturase activity of Fusarium oxysporum microsomes
Can. J. Biochem.
58
97-102
1980
Fusarium oxysporum
Manually annotated by BRENDA team
Murphy, D.J.; Mukherjee, K.D.; Latzko, E.
Lipid metabolism in microsomal fraction from photosynthetic tissue. Effects of catalase and hydrogen peroxide on oleate desaturation
Biochem. J.
213
249-252
1983
Pisum sativum
Manually annotated by BRENDA team
Hawke, J.C.; Stumpf, P.K.
Desaturation of oleic and linoleic acids by leaves of dark- and light-grown maize seedlings
Plant Physiol.
65
1027-1030
1980
Zea mays
Manually annotated by BRENDA team
Slack, C.R.; Grattan Roughan, P.; Browse, J.
Evidence for an oleoyl phosphatidylcholine desaturase in microsomal preparations from cotyledons of safflower (Carthamus tinctorius) seed
Biochem. J.
179
649-656
1979
Carthamus tinctorius, Carthamus tinctorius cultivar 0-22
Manually annotated by BRENDA team
Pugh, E.L.; Kates, M.
Characterization of a membrane-bound phospholipid desaturase system of candida lipolytica
Biochim. Biophys. Acta
380
442-453
1975
Yarrowia lipolytica
Manually annotated by BRENDA team
Sarmiento, C.; Garces, R.; Mancha, M.
Oleate desaturation and acyl turnover in sunflower (Helianthus annuus L.) seed lipids during rapid temperature adaption
Planta
205
595-600
1998
Helianthus annuus
-
Manually annotated by BRENDA team
Gray, D.A.; Kekwick, R.G.O.
Intracellular location of oleate desaturase and associated constituents in developing sunflower (Helianthus annuus) seeds
Plant Sci.
119
11-21
1996
Helianthus annuus
-
Manually annotated by BRENDA team
Gray, D.A.; Kekwick, R.G.O.
Oleate desaturase activity in sunflower (Helianthus annuus) seeds and its relation to associated constituents during seed development
Plant Sci.
115
39-47
1996
Helianthus annuus
-
Manually annotated by BRENDA team
Garcia-Diaz, M.T.; Martinez-Rivas, J.M.; Mancha, M.
Temperature and oxygen regulation of oleate desaturation in developing sunflower (Helianthus annuus) seeds
Physiol. Plant.
114
13-20
2002
Helianthus annuus
Manually annotated by BRENDA team
Petrini, G.A.; Altabe, S.G.; Uttaro, A.D.
Trypanosoma brucei oleate desaturase may use a cytochrome b5-like domain in another desaturase as an electron donor
Eur. J. Biochem.
271
1079-1086
2004
Trypanosoma brucei (Q6UCJ6), Trypanosoma brucei
Manually annotated by BRENDA team
Esteban, A.B.; Sicardo, M.D.; Mancha, M.; Martinez-Rivas, J.M.
Growth temperature control of the linoleic acid content in safflower (Carthamus tinctorius) seed oil
J. Agric. Food Chem.
52
332-336
2004
Carthamus tinctorius
Manually annotated by BRENDA team
Broadwater, J.A.; Whittle, E.; Shanklin, J.
Desaturation and hydroxylation. Residues 148 and 324 of Arabidopsis FAD2, in addition to substrate chain length, exert a major influence in partitioning of catalytic specificity
J. Biol. Chem.
277
15613-15620
2002
Arabidopsis thaliana
Manually annotated by BRENDA team
Wilson, R.A.; Calvo, A.M.; Chang, P.K.; Keller, N.P.
Characterization of the Aspergillus parasiticus DELTA12-desaturase gene: A role for lipid metabolism in the Aspergillus-seed interaction
Microbiology
150
2881-2888
2004
Aspergillus parasiticus
Manually annotated by BRENDA team
Martinez-Rivas, J.M.; Sanchez-Garcia, A.; Sicardo, M.D.; Garcia-Diaz, M.T.; Mancha, M.
Oxygen-independent temperature regulation of the microsomal oleate desaturase (FAD2) activity in developing sunflower (Helianthus annuus) seeds
Physiol. Plant.
117
179-185
2003
Helianthus annuus
-
Manually annotated by BRENDA team
Maldonado, R.A.; Kuniyoshi, R.K.; Linss, J.G.; Almeida, I.C.
Trypanosoma cruzi oleate desaturase: molecular characterization and comparative analysis in other trypanosomatids
J. Parasitol.
92
1064-1074
2006
Trypanosoma cruzi
Manually annotated by BRENDA team
Li, L.; Wang, X.; Gai, J.; Yu, D.
Molecular cloning and characterization of a novel microsomal oleate desaturase gene from soybean
J. Plant Physiol.
164
1516-1526
2007
Glycine max (Q19AK7), Glycine max
Manually annotated by BRENDA team
Schuppert, G.F.; Tang, S.; Slabaugh, M.B.; Knapp, S.J.
The sunflower high-oleic mutant Ol carries variable tandem repeats of FAD2-1, a seed-specific oleoyl-phosphatidyl choline desaturase
Mol. Breed.
17
241-256
2006
Helianthus annuus
Manually annotated by BRENDA team
Kim, M.J.; Kim, H.; Shin, J.S.; Chung, C.H.; Ohlrogge, J.B.; Suh, M.C.
Seed-specific expression of sesame microsomal oleic acid desaturase is controlled by combinatorial properties between negative cis-regulatory elements in the SeFAD2 promoter and enhancers in the 5-UTR intron
Mol. Genet. Genomics
276
351-368
2006
Sesamum indicum
Manually annotated by BRENDA team
Banilas, G.; Moressis, A.; Nikoloudakis, N.; Hatzopoulos, P.
Spatial and temporal expressions of two distinct oleate desaturases from olive (Olea europaea L.)
Plant Sci.
168
547-555
2005
Olea europaea (Q8GVC9)
Manually annotated by BRENDA team
Reza, M.A.; Goldenkova-Pavlova, I.V.; Pchelkin, V.P.; Tsydendambaev, V.D.; Los, D.A.; Nosov, A.M.
Acyl-lipid DELTA12-desaturase of the cyanobacterium increases the unsaturation degree in transgenic potato (Solanum tuberosum L.)
Biologia
53
4-7
2007
Synechocystis sp.
-
Manually annotated by BRENDA team
Chu, Y.; Ramos, L.; Holbrook, C.C.; Ozias-Akins, P.
Frequency of a loss-of-function mutation in oleoyl-PC desaturase (ahFAD2A) in the mini-core of the U.S. peanut germplasm collection
Crop Sci.
47
2372-2378
2007
Arachis hypogaea
-
Manually annotated by BRENDA team
Li, L.; Wang, X.; Gai, J.; Yu, D.
Isolation and characterization of a seed-specific isoform of microsomal omega-6 fatty acid desaturase gene (FAD2-1B) from soybean
DNA Seq.
19
28-36
2008
Glycine max (Q19AK8), Glycine max
Manually annotated by BRENDA team
Rolletschek, H.; Borisjuk, L.; Sanchez-Garcia, A.; Gotor, C.; Romero, L.C.; Martinez-Rivas, J.M.; Mancha, M.
Temperature-dependent endogenous oxygen concentration regulates microsomal oleate desaturase in developing sunflower seeds
J. Exp. Bot.
58
3171-3181
2007
Helianthus annuus
Manually annotated by BRENDA team
Kargiotidou, A.; Deli, D.; Galanopoulou, D.; Tsaftaris, A.; Farmaki, T.
Low temperature and light regulate delta 12 fatty acid desaturases (FAD2) at a transcriptional level in cotton (Gossypium hirsutum)
J. Exp. Bot.
59
2043-2056
2008
Gossypium hirsutum (Q8W2B9), Gossypium hirsutum
Manually annotated by BRENDA team
Hernandez, M.L.; Padilla, M.N.; Mancha, M.; Martinez-Rivas, J.M.
Expression analysis identifies FAD2-2 as the olive oleate desaturase gene mainly responsible for the linoleic acid content in virgin olive oil
J. Agric. Food Chem.
57
6199-6206
2009
Olea europaea (A9UKE1), Olea europaea (Q4QWZ0), Olea europaea (Q4QWZ1)
Manually annotated by BRENDA team
Lacombe, S.; Souyris, I.; Berville, A.J.
An insertion of oleate desaturase homologous sequence silences via siRNA the functional gene leading to high oleic acid content in sunflower seed oil
Mol. Genet. Genomics
281
43-54
2009
Helianthus annuus (O24499)
Manually annotated by BRENDA team
Dierking, E.C.; Bilyeu, K.D.
New sources of soybean seed meal and oil composition traits identified through TILLING
BMC Plant Biol.
9
89
2009
Glycine max
Manually annotated by BRENDA team
Amiri, R.M.; Yureva, N.O.; Shimshilashvili, K.R.; Goldenkova-Pavlova, I.V.; Pchelkin, V.P.; Kuznitsova, E.I.; Tsydendambaev, V.D.; Trunova, T.I.; Los, D.A.; Jouzani, G.S.; Nosov, A.M.
Expression of acyl-lipid Delta12-desaturase gene in prokaryotic and eukaryotic cells and its effect on cold stress tolerance of potato
J. Integr. Plant Biol.
52
289-297
2010
Synechocystis sp.
Manually annotated by BRENDA team
Song, W.; Maeda, H.; DellaPenna, D.
Mutations of the ER to plastid lipid transporters TGD1, 2, 3 and 4 and the ER oleate desaturase FAD2 suppress the low temperature-induced phenotype of Arabidopsis tocopherol-deficient mutant vte2
Plant J.
62
1004-1018
2010
Arabidopsis thaliana
Manually annotated by BRENDA team
Lei, N.; Peng, S.; Niu, B.; Chen, J.; Zhou, J.; Tang, L.; Xu, Y.; Wang, S.; Chen, F.
Molecular cloning and characterization of a novel microsomal oleate desaturase gene DiFAD2 from Davidia involucrata Baill
Biol. Plant.
54
41-46
2010
Davidia involucrata
-
Manually annotated by BRENDA team
Pham, A.T.; Lee, J.D.; Shannon, J.G.; Bilyeu, K.D.
Mutant alleles of FAD2-1A and FAD2-1B combine to produce soybeans with the high oleic acid seed oil trait
BMC Plant Biol.
10
195
2010
Glycine max
Manually annotated by BRENDA team
Yan, Z.; Zhuo, L.; Mulan, J.; Xia, W.; Yangmin, G.; Yinbo, Z.; Fenghong, H.
Clone and identification of bifunctional DELTA12/DELTA15 fatty acid desaturase LKFAD15 from Lipomyces kononenkoae
Food Sci. Biotechnol.
22
573-576
2013
Lipomyces kononenkoae (H9CP21)
-
Manually annotated by BRENDA team
Matsuda, T.; Sakaguchi, K.; Kobayashi, T.; Abe, E.; Kurano, N.; Sato, A.; Okita, Y.; Sugimoto, S.; Hama, Y.; Hayashi, M.; Okino, N.; Ito, M.
Molecular cloning of a Pinguiochrysis pyriformis oleate-specific microsomal DELTA12-fatty acid desaturase and functional analysis in yeasts and thraustochytrids
J. Biochem.
150
375-383
2011
Pinguiochrysis pyriformis
Manually annotated by BRENDA team
Zhou, X.; Green, A.; Singh, S.
Caenorhabditis elegans ?12-desaturase FAT-2 is a bifunctional desaturase able to desaturate a diverse range of fatty acid substrates at the DELTA12 and DELTA15 positions
J. Biol. Chem.
286
43644-43650
2011
Caenorhabditis elegans
Manually annotated by BRENDA team
Matsuda, T.; Sakaguchi, K.; Hamaguchi, R.; Kobayashi, T.; Abe, E.; Hama, Y.; Hayashi, M.; Honda, D.; Okita, Y.; Sugimoto, S.; Okino, N.; Ito, M.
Analysis of DELTA12-fatty acid desaturase function revealed that two distinct pathways are active for the synthesis of PUFAs in T. aureum ATCC 34304
J. Lipid Res.
53
1210-1222
2012
Thraustochytrium aureum, Thraustochytrium aureum ATCC 3404
Manually annotated by BRENDA team
Shi, J.; Cao, Y.; Fan, X.; Li, M.; Wang, Y.; Ming, F.
A rice microsomal delta-12 fatty acid desaturase can enhance resistance to cold stress in yeast and Oryza sativa
Mol. Breed.
29
743-757
2012
Oryza sativa
-
Manually annotated by BRENDA team
Jung, J.H.; Kim, H.; Go, Y.S.; Lee, S.B.; Hur, C.G.; Kim, H.U.; Suh, M.C.
Identification of functional BrFAD2-1 gene encoding microsomal delta-12 fatty acid desaturase from Brassica rapa and development of Brassica napus containing high oleic acid contents
Plant Cell Rep.
30
1881-1892
2011
Brassica rapa
Manually annotated by BRENDA team
Guan, L.; Xu, Y.; Wang, Y.; Chen, L.; Shao, J.; Wu, W.
Isolation and characterization of a temperature-regulated microsomal oleate desaturase gene (CtFAD2-1) from Safflower (Carthamus tinctorius L.)
Plant Mol. Biol. Rep.
30
391-402
2012
Carthamus tinctorius
-
Manually annotated by BRENDA team
Kang, J.; Snapp, A.R.; Lu, C.
Identification of three genes encoding microsomal oleate desaturases (FAD2) from the oilseed crop Camelina sativa
Plant Physiol. Biochem.
49
223-229
2011
Camelina sativa
Manually annotated by BRENDA team
Kearns, E.V.; Hugly, S.; Somerville, C.R.
The role of cytochrome b5 in DELTA12 desaturation of oleic acid by microsomes of safflower (Carthamus tinctorius L.)
Arch. Biochem. Biophys.
284
431-436
1991
Carthamus tinctorius
Manually annotated by BRENDA team
Smith, M.A.; Cross, A.R.; Jones, O.T.; Griffiths, W.T.; Stymne, S.; Stobart, K.
Electron-transport components of the 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine DELTA 12-desaturase (DELTA12-desaturase) in microsomal preparations from developing safflower (Carthamus tinctorius L.) cotyledons
Biochem. J.
272
23-29
1990
Carthamus tinctorius, Carthamus tinctorius var High Linoleate
Manually annotated by BRENDA team
Smith, M.A.; Jonsson, L.; Stymne, S.; Stobart, K.
Evidence for cytochrome b5 as an electron donor in ricinoleic acid biosynthesis in microsomal preparations from developing castor bean (Ricinus communis L.)
Biochem. J.
287
141-144
1992
Ricinus communis
Manually annotated by BRENDA team
Sperling, P.; Schmidt, H.; Heinz, E.
A cytochrome-b5-containing fusion protein similar to plant acyl lipid desaturases
Eur. J. Biochem.
232
798-805
1995
Helianthus annuus
Manually annotated by BRENDA team
Miquel, M.; Browse, J.
Arabidopsis mutants deficient in polyunsaturated fatty acid synthesis. Biochemical and genetic characterization of a plant oleoyl-phosphatidylcholine desaturase
J. Biol. Chem.
267
1502-1509
1992
Arabidopsis thaliana
Manually annotated by BRENDA team
Caiveau, O.; Fortune, D.; Cantrel, C.; Zachowski, A.; Moreau, F.
Consequences of omega-6-oleate desaturase deficiency on lipid dynamics and functional properties of mitochondrial membranes of Arabidopsis thaliana
J. Biol. Chem.
276
5788-5794
2001
Arabidopsis thaliana (P46313), Arabidopsis thaliana
Manually annotated by BRENDA team
Yang, M.; Xu, Y.
Oleate accumulation, induced by silencing of microsomal omega-6 desaturase, declines with leaf expansion in transgenic tobacco
J. Plant Physiol.
164
23-30
2007
Nicotiana tabacum (Q6DMQ8), Nicotiana tabacum
Manually annotated by BRENDA team
Okuley, J.; Lightner, J.; Feldmann, K.; Yadav, N.; Lark, E.; Browse, J.
Arabidopsis FAD2 gene encodes the enzyme that is essential for polyunsaturated lipid synthesis
Plant Cell
6
147-158
1994
Arabidopsis thaliana (P46313)
Manually annotated by BRENDA team
Kumar, R.; Tran, L.S.; Neelakandan, A.K.; Nguyen, H.T.
Higher plant cytochrome b5 polypeptides modulate fatty acid desaturation
PLoS ONE
7
e31370
2012
Arabidopsis thaliana (P46313), Glycine max
Manually annotated by BRENDA team
Dehghan Nayeri, F.; Yarizade, K.
Bioinformatics study of delta-12 fatty acid desaturase 2 (FAD2) gene in oilseeds
Mol. Biol. Rep.
41
5077-5087
2014
Linum usitatissimum (B7ST72), Arachis hypogaea (E1A444), Linum grandiflorum (G4Y082), Helianthus annuus (Q8W2F0), Sesamum indicum (Q9LLL7), Vernonia galamensis (Q9SP28)
Manually annotated by BRENDA team