Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Reference on EC 1.14.13.148 - trimethylamine monooxygenase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Adali, O.; Carver, G.C.; Philpot, R.M.
The effect of arginine-428 mutation on modulation of activity of human liver flavin monooxygenase 3 (FMO3) by imipramine and chlorpromazine
Exp. Toxicol. Pathol.
51
271-276
1999
Homo sapiens
Manually annotated by BRENDA team
Klick, D.E.; Shadley, J.D.; Hines, R.N.
Differential regulation of human hepatic flavin containing monooxygenase 3 (FMO3) by CCAAT/enhancer-binding protein beta (C/EBPbeta) liver inhibitory and liver activating proteins
Biochem. Pharmacol.
76
268-278
2008
Homo sapiens
Manually annotated by BRENDA team
Lickteig, A.J.; Riley, R.; Melton, R.J.; Reitz, B.A.; Fischer, H.D.; Stevens, J.C.
Expression and characterization of functional dog flavin-containing monooxygenase 3
Drug Metab. Dispos.
37
1987-1990
2009
Canis lupus familiaris, Homo sapiens
Manually annotated by BRENDA team
Henderson, M.C.; Siddens, L.K.; Morre, J.T.; Krueger, S.K.; Williams, D.E.
Metabolism of the anti-tuberculosis drug ethionamide by mouse and human FMO1, FMO2 and FMO3 and mouse and human lung microsomes
Toxicol. Appl. Pharmacol.
233
420-427
2008
Homo sapiens (P31513), Mus musculus (P97501)
Manually annotated by BRENDA team
Large, P.; Boulton, C.; Crabbe, M.
The reduced nicotinamide-adenine dinucleotide phosphate- and oxygen-dependent N-oxygenation of trimethylamine by Pseudomonas aminovorans
Biochem. J.
128
137P-138P
1972
Aminobacter aminovorans
Manually annotated by BRENDA team
Lang, D.H.; Yeung, C.K.; Peter, R.M.; Ibarra, C.; Gasser, R.; Itagaki, K.; Philpot, R.M.; Rettie, A.E.
Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes: selective catalysis by FMO3
Biochem. Pharmacol.
56
1005-1012
1998
Homo sapiens
Manually annotated by BRENDA team
Catucci, G.; Gilardi, G.; Jeuken, L.; Sadeghi, S.
In vitro drug metabolism by C-terminally truncated human flavin-containing monooxygenase 3
Biochem. Pharmacol.
83
551-558
2012
Homo sapiens
Manually annotated by BRENDA team
Strm, A.
Biosynthesis of trimethylamine oxide in Calanus finmarchicus. Properties of a soluble trimethylamine monooxygenase
Comp. Biochem. Physiol. B
65
243-249
1980
Calanus finmarchicus
-
Manually annotated by BRENDA team
Haining, R.; Hunter, A.; Sadeque, A.; Philpot, R.; Rettie, A.
Baculovirus-mediated expression and purification of human FMO3: Catalytic, immunochemical, and structural characterization
Drug Metab. Dispos.
25
790-797
1997
Homo sapiens
Manually annotated by BRENDA team
Gut, I.; Conney, A.H.
The FAD-containing monooxygenase-catalyzed N-oxidation and demethylation of trimethylamine in rat liver microsomes
Drug Metabol. Drug Interact.
9
201-208
1991
Rattus norvegicus
Manually annotated by BRENDA team
Dolphin, C.; Riley, J.; Smith L, R.; Shephard, E.; Phillips, I.
Structural organization of the human flavin-containing monooxygenase 3 gene (FMO3), the favored candidate for fish-odor syndrome, determined directly from genomic DNA
Genomics
46
260-267
1997
Homo sapiens (P31513)
Manually annotated by BRENDA team
Treacy, E.; Akerman, B.; Chow, L.; Youil, R.; Bibeau, C.; Lin, J.; Bruce, A.; Knight, M.; Danks, D.; Cashman, J.; Forrest, S.
Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication
Hum. Mol. Genet.
7
839-845
1998
Homo sapiens
Manually annotated by BRENDA team
Burnettt, V.; Lawton, M.; Philpot, R.
Cloning and sequencing of flavin-containing monooxygenases FMO3 and FMO4 from rabbit and characterization of FMO3
J. Biol. Chem.
269
14314-14322
1994
Oryctolagus cuniculus (P32417), Oryctolagus cuniculus (P36367)
Manually annotated by BRENDA team
Koukouritaki, S.; Poch, M.; Cabacungan, E.; McCarver, D.; Hines, R.
Discovery of novel flavin-containing monooxygenase 3 (FMO3) single nucleotide polymorphisms and functional analysis of upstream haplotype variants
Mol. Pharmacol.
68
383-392
2005
Homo sapiens (P31513)
Manually annotated by BRENDA team
Chen, Y.; Patel, N.A.; Crombie, A.; Scrivens, J.H.; Murrell, J.C.
Bacterial flavin-containing monooxygenase is trimethylamine monooxygenase
Proc. Natl. Acad. Sci. USA
108
17791-17796
2011
Ruegeria pomeroyi, Roseovarius sp., Candidatus Pelagibacter ubique, no activity in Oceanicola batsensis, no activity in Roseobacter sp., no activity in Sagittula stellata, Methylocella silvestris, no activity in Dinoroseobacter shibae, Candidatus Pelagibacter ubique HTCC7211, no activity in Roseobacter sp. SK209-2-6, Candidatus Pelagibacter ubique HTCC1002, Roseovarius sp. 217
Manually annotated by BRENDA team
Mitchell, S.; Smith, R.
A physiological role for flavin-containing monooxygenase (FMO3) in humans
Xenobiotica
40
301-305
2010
Homo sapiens
Manually annotated by BRENDA team
Fedejko-Kap, B.; Niemira, M.; Radominska-Pandya, A.; Mazerska, Z.
Flavin monooxygenases, FMO1 and FMO3, not cytochrome P450 isoenzymes, contribute to metabolism of anti-tumour triazoloacridinone, C-1305, in liver microsomes and HepG2 cells
Xenobiotica
41
1044-1055
2011
Rattus norvegicus, Homo sapiens (P31513)
Manually annotated by BRENDA team
Goris, M.; Puntervoll, P.; Rojo, D.; Claussen, J.; Larsen, .; Garcia-Moyano, A.; Almendral, D.; Barbas, C.; Ferrer, M.; Bjerga, G.
Use of flavin-containing monooxygenases for conversion of trimethylamine in salmon protein hydrolysates
Appl. Environ. Microbiol.
86
e02105-20
2020
Methylophaga aminisulfidivorans, Nocardiopsis alba, Micrococcus terreus (A0A1I7MIR7), Methylophaga aminisulfidivorans SK1
Manually annotated by BRENDA team
Wang, X.; Zhang, N.; Teng, Z.; Wang, P.; Zhang, W.; Chen, X.; Zhang, Y.; Chen, Y.; Fu, H.; Li, C.
Structural and mechanistic insights into dimethylsulfoxide formation through dimethylsulfide oxidation
Front. Microbiol.
12
735793
2021
Candidatus Pelagibacter sp. HTCC7211 (B6BT33)
Manually annotated by BRENDA team