Information on EC 1.14.11.24 - 2'-deoxymugineic-acid 2'-dioxygenase

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The expected taxonomic range for this enzyme is: Hordeum vulgare

EC NUMBER
COMMENTARY
1.14.11.24
-
RECOMMENDED NAME
GeneOntology No.
2'-deoxymugineic-acid 2'-dioxygenase
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
2'-deoxymugineic acid + 2-oxoglutarate + O2 = mugineic acid + succinate + CO2
show the reaction diagram
-
-
-
-
PATHWAY
KEGG Link
MetaCyc Link
hydroxylated mugineic acid phytosiderophore biosynthesis
-
SYSTEMATIC NAME
IUBMB Comments
2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating)
Requires iron(II). It is also likely that this enzyme can catalyse the hydroxylation of 3-epihydroxy-2'-deoxymugineic acid to form 3-epihydroxymugineic acid.
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
IDS3
-
gene name
IDS3
Q40062
-
mugineicacid synthase
-
-
CAS REGISTRY NUMBER
COMMENTARY
133758-62-0
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
gene IDS3
-
-
Manually annotated by BRENDA team
L. cv. Ehimehadaka
SwissProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
additional information
-
concomitant introduction of the Glycine max ferritin gene and Hordeum vulgare mugineic acid biosynthetic genes effectively increases the seed iron level without causing iron sensitivity under iron-limited conditions in Oryza sativa, overview
SUBSTRATE
PRODUCT                      
REACTION DIAGRAM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
(Substrate)
LITERATURE
(Substrate)
COMMENTARY
(Product)
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2'-deoxymugineic acid + 2-oxoglutarate + O2
mugineic acid + succinate + CO2
show the reaction diagram
-
-
-
-
?
2'-deoxymugineic acid + 2-oxoglutarate + O2
mugineic acid + succinate + CO2
show the reaction diagram
Q40062
-
-
-
?
3-epihydroxy-2'-deoxymugineic acid + 2-oxoglutarate + O2
? + succinate + CO2
show the reaction diagram
Q40062
-
-
-
?
pI VALUE
pI VALUE MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
6
-
Q40062
-
SOURCE TISSUE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
SOURCE
-
specifically expressed in roots of iron-deficient barley
Manually annotated by BRENDA team
SUBUNITS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
?
Q40062
x * 37700, calculation from nucleotide sequence
Cloned/COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
expression in Escherichia coli
Q40062
introduction of the Ids3 gene into Oryza sativa cultivar Nipponbare and Tsukinohikari which lack Ids3 homologues
-
ENGINEERING
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
additional information
-
introduction of Glycine max ferritin gene driven by two endosperm-specific promoters, along with Hordeum vulgare nicotianamine synthase gene HvNAS, two nicotianamine aminotransferase genes HvNAAT-A and -B, and mugineic acid synthase gene IDS3 to enhance mugineic acid production in Oryza sativa sp. japonica cv. Tsukinohikari plant seeds. Lines expressing both ferritin and mugineic acid biosynthetic genes show signs of iron-deficiency tolerance in calcareous soil, phenotypes, overview