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Information on EC 1.1.99.41 - 3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine reductase

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EC Tree
IUBMB Comments
This enzyme is involved in the biosynthesis of vindoline and vindorosine in the plant Catharanthus roseus (Madagascar periwinkle). In vivo, it functions in the direction of reduction. It has no activity with 3-epoxylated compounds, which can form spontaneously from its unstable substrates.
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The expected taxonomic range for this enzyme is: Catharanthus roseus
Synonyms
tabersonine 3-reductase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + acceptor = (3R)-3-hydroxy-16-methoxy-1,2-didehydro-2,3-dihydrotabersonine + reduced acceptor
show the reaction diagram
(1)
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(3R)-3-hydroxy-2,3-dihydrotabersonine + acceptor = (3R)-3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine + reduced acceptor
show the reaction diagram
(1)
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