Information on EC 1.1.1.258 - 6-hydroxyhexanoate dehydrogenase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
1.1.1.258
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RECOMMENDED NAME
GeneOntology No.
6-hydroxyhexanoate dehydrogenase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
6-hydroxyhexanoate + NAD+ = 6-oxohexanoate + NADH + H+
show the reaction diagram
Involved in the cyclohexanol degradation pathway in Acinetobacter NCIB 9871
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
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redox reaction
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-
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reduction
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Caprolactam degradation
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cyclohexanol degradation
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Microbial metabolism in diverse environments
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cyclohexanol degradation
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SYSTEMATIC NAME
IUBMB Comments
6-hydroxyhexanoate:NAD+ oxidoreductase
Involved in the cyclohexanol degradation pathway in Acinetobacter NCIB 9871.
CAS REGISTRY NUMBER
COMMENTARY hide
77000-03-4
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
strain NCIB 9871
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Manually annotated by BRENDA team
strain NCIB 9871
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Manually annotated by BRENDA team
strain CL1
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Manually annotated by BRENDA team
strain CL1
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Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
6-hydroxyhexanoate + NAD+
6-oxohexanoate + NADH
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
6-hydroxyhexanoate + NAD+
6-oxohexanoate + NADH
show the reaction diagram
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
NAD+
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can not be replaced by NADP+
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
very labile to storage
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