Reference on EC 1.1.1.206 - tropinone reductase I

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Koelen, K.J.; Gross, G.G.
Partial purification and properties of tropine dehydrogenase from root cultures of Datura stramonium
J. Med. Plant Res.
44
227-230
1982
Datura stramonium
Manually annotated by BRENDA team
Nakajima, K.; Hashimoto, T.; Yamada, Y.
Opposite stereospecificity of two tropinone reductases is conferred by the substrate-binding sites
J. Biol. Chem.
269
11695-11698
1994
Datura stramonium
Manually annotated by BRENDA team
Bartholomew, B.A.; Smith, M.J.; Long, M.T.; Darcy, P.J.; Trudgill P.W.; Hopper, K.J.
Tropine dehydrogenase: purification, some properties and an evaluation of its role in the bacterial metabolism of tropine
Biochem. J.
307
603-608
1995
Pseudomonas sp., Pseudomonas sp. AT3
-
Manually annotated by BRENDA team
Nakajima, K.; Kato, H.; Oda, J.; Yamada, Y.; Hashimoto, T.
Site-directed mutagenesis of putative substrate-binding residues reveals a mechanism controlling the different stereospecificities of two tropinone reductases
J. Biol. Chem.
274
16563-16568
1999
Datura stramonium
Manually annotated by BRENDA team
Boswell, H.D.; Dräger, B.; McLauchlan W.R.; Portsteffen, A.; Robins D.J.; Robins R.J.; Walton, N.J.
Specificities of the enzymes of N-alkyltropane biosynthesis in Brugmansia and Datura
Phytochemistry
52
871-878
1999
Brugmansia sp., Datura stramonium
Manually annotated by BRENDA team
Hashimoto, T.; Nakajima, K.; Ongena, G.; Yamada, Y.
Two tropinone reductases with distinct stereospecificities from cultured roots of Hyoscyamus niger
Plant Physiol.
100
836-845
1992
Atropa acuminata, Atropa belladonna, Datura stramonium, Duboisia hopwoodii, Duboisia leichhardtii, Hyoscyamus albus, Hyoscyamus bohemicus, Hyoscyamus canariensis, Hyoscyamus muticus, Hyoscyamus niger, Hyoscyamus niger Hn, Hyoscyamus pusillus, no activity in Brassica campestris, no activity in Browallia americana, no activity in Calystegia sepium, no activity in Nicotiana tabacum, no activity in Physalis alkekengi, Physalis edulis, Physalis philadelphica, Physochlaina orientalis
Manually annotated by BRENDA team
Nakajima, K.; Yamashita, A.; Akama, H.; Nakatsu, T.; Kato, H.; Hashimoto, T.; Oda, J.; Yamada, Y.
Crystal structures of two tropinone reductases: Different reaction stereospecificities in the same protein fold
Proc. Natl. Acad. Sci. USA
95
4876-4881
1998
Datura stramonium
Manually annotated by BRENDA team
Rocha, P.; Stenzel, O.; Parr, A.; Walton, N.; Christou, P.; Drager, B.; Leech, M.J.
Functional expression of tropinone reductase I (trI) and hyoscyamine-6beta-hydroxylase (h6h) from Hyoscyamus niger in Nicotiana tabacum
Plant Sci.
162
905-913
2002
Hyoscyamus niger
-
Manually annotated by BRENDA team
Richter, U.; Rothe, G.; Fabian, A.K.; Rahfeld, B.; Drager, B.
Overexpression of tropinone reductases alters alkaloid composition in Atropa belladonna root cultures
J. Exp. Bot.
56
645-652
2005
Atropa belladonna, Datura stramonium (P50162)
Manually annotated by BRENDA team
Draeger, B.
Tropinone reductases, enzymes at the branch point of tropane alkaloid metabolism
Phytochemistry
67
327-337
2006
Atropa belladonna, Datura stramonium, Duboisia leichhardtii, Duboisia myoporoides, Hyoscyamus muticus, Hyoscyamus niger, Scopolia atropoides
Manually annotated by BRENDA team
Brock, A.; Brandt, W.; Draeger, B.
The functional divergence of short-chain dehydrogenases involved in tropinone reduction
Plant J.
54
388-401
2008
Cochlearia officinalis (A7DY56)
Manually annotated by BRENDA team
Freydank, A.C.; Brandt, W.; Draeger, B.
Protein structure modeling indicates hexahistidine-tag interference with enzyme activity
Proteins
72
173-183
2008
Solanum dulcamara
Manually annotated by BRENDA team
Kai, G.; Li, L.; Jiang, Y.; Yan, X.; Zhang, Y.; Lu, X.; Liao, P.; Chen, J.
Molecular cloning, characterization of two tropinone reductases in Anisodus acutangulus and enhancement of tropane alkaloids production in AaTRI-transformed hairy roots
Biotechnol. Appl. Biochem.
54
:177-186
2009
Anisodus acutangulus (B2L2W8)
Manually annotated by BRENDA team
Kai, G.; Yang, S.; Luo, X.; Zhou, W.; Fu, X.; Zhang, A.; Zhang, Y.; Xiao, J.
Co-expression of AaPMT and AaTRI effectively enhances the yields of tropane alkaloids in Anisodus acutangulus hairy roots
BMC Biotechnol.
11
43
2011
Anisodus acutangulus, Anisodus acutangulus (B2L2W8)
Manually annotated by BRENDA team
Kushwaha, A.K.; Sangwan, N.S.; Tripathi, S.; Sangwan, R.S.
Molecular cloning and catalytic characterization of a recombinant tropine biosynthetic tropinone reductase from Withania coagulans leaf
Gene
516
238-247
2013
Withania coagulans (L7QI79), Withania coagulans
Manually annotated by BRENDA team
Kai, G.; Zhang, A.; Guo, Y.; Li, L.; Cui, L.; Luo, X.; Liu, C.; Xiao, J.
Enhancing the production of tropane alkaloids in transgenic Anisodus acutangulus hairy root cultures by over-expressing tropinone reductase I and hyoscyamine-6beta-hydroxylase
Mol. Biosyst.
8
2883-2890
2012
Anisodus acutangulus, Anisodus acutangulus (B2L2W8)
Manually annotated by BRENDA team
Dehghan, E.; Shahriari Ahmadi, F.; Ghotbi Ravandi, E.; Reed, D.W.; Covello, P.S.; Bahrami, A.R.
An atypical pattern of accumulation of scopolamine and other tropane alkaloids and expression of alkaloid pathway genes in Hyoscyamus senecionis
Plant Physiol. Biochem.
70C
188-194
2013
Hyoscyamus muticus, Hyoscyamus senecionis
Manually annotated by BRENDA team