Information on EC 1.1.1.202 - 1,3-propanediol dehydrogenase

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The expected taxonomic range for this enzyme is: Bacteria

EC NUMBER
COMMENTARY
1.1.1.202
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RECOMMENDED NAME
GeneOntology No.
1,3-propanediol dehydrogenase
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT ACCESSION NO.
LITERATURE
propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH + H+
show the reaction diagram
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REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
oxidation
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redox reaction
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-
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reduction
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PATHWAY
KEGG Link
MetaCyc Link
glycerol degradation III
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Glycerolipid metabolism
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SYSTEMATIC NAME
IUBMB Comments
propane-1,3-diol:NAD+ 1-oxidoreductase
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SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
(NADH)-linked 1,3-PD oxidoreductase
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1,3-PD dehydrogenase
Q7WRJ3
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1,3-PD oxidoreductase
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1,3-PD oxidoreductase
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1,3-PD oxidoreductase
Klebsiella pneumoniae Cu, Klebsiella pneumoniae KG1
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1,3-PD:NAD+ oxidoreductase
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1,3-Pdiol dehydrogenase
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1,3-Pdiol dehydrogenase
Clostridium butyricum VPI 3266
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1,3-propanediol dehydrogenase
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1,3-propanediol oxidoreductase
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1,3-propanediol oxidoreductase
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1,3-propanediol oxidoreductase
Escherichia coli SYU
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1,3-propanediol oxidoreductase
Q7WRJ3
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1,3-propanediol oxidoreductase
Klebsiella pneumoniae DSM2026, Klebsiella pneumoniae KG1, Klebsiella pneumoniae M5a1
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1,3-propanediol-oxidoreductase
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1,3-propanediol-oxidoreductase
Klebsiella pneumoniae DSM2026
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1,3-propanediol:NAD oxidoreductase
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3-hydroxypropionaldehyde reductase
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ADH3
A0NIJ1
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dehydrogenase, 1,3-propanediol
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DhaT
P45513
gene name
DhaT
Q59477
gene name
DhaT
Klebsiella pneumoniae Cu
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DhaT
A0NIJ1
gene name
DhaT
A0NIJ1
gene name
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lr_0030
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gene name
lr_1734
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gene name
NADH-linked 1,3-propanediol oxidoreductase
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PDOR
Klebsiella pneumoniae KG1, Klebsiella pneumoniae M5a1
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PDOR
Klebsiella pneumoniae TUAC01
A3RL85
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YqhD
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gene name
YqhD
Escherichia coli SYU
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CAS REGISTRY NUMBER
COMMENTARY
81611-70-3
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ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
LMG 1212t2
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Manually annotated by BRENDA team
strain VPI 3266
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Manually annotated by BRENDA team
Clostridium butyricum E5
E5
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Manually annotated by BRENDA team
Clostridium butyricum LMG 1212t2
LMG 1212t2
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Manually annotated by BRENDA team
Clostridium butyricum VPI 3266
strain VPI 3266
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Manually annotated by BRENDA team
Clostridium pasteurianum LMG 3285
LMG 3285
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Manually annotated by BRENDA team
strain SYU 21132
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Manually annotated by BRENDA team
Escherichia coli SYU
strain SYU 21132
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Manually annotated by BRENDA team
gene dhaT, strain DSM 2026
SwissProt
Manually annotated by BRENDA team
strain Cu, derivative of ATCC 200721
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Manually annotated by BRENDA team
strain DSM 2026, gene dhaT
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Manually annotated by BRENDA team
strain DSMZ 2026
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Manually annotated by BRENDA team
strain M5a1
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Manually annotated by BRENDA team
strain TUAC01, gene dhaT
UniProt
Manually annotated by BRENDA team
Klebsiella pneumoniae Cu
strain Cu, derivative of ATCC 200721
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Manually annotated by BRENDA team
Klebsiella pneumoniae DSM2026
DSM2026
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Manually annotated by BRENDA team
Klebsiella pneumoniae M5a1
strain M5a1
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-
Manually annotated by BRENDA team
Klebsiella pneumoniae TUAC01
strain TUAC01, gene dhaT
UniProt
Manually annotated by BRENDA team
gene TM0920, strain MSB8
SwissProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
physiological function
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growth behaviour on glucose is comparable between the wild type and a mutant strain lacking ORF lr0030. On glucose plus glycerol, the exponential growth rate of the lr_0030 mutant is lower compared to the wild type. Glycerol addition results in decreased ethanol production in the wild type, but not in lr_0030 mutant. Activity measurements using 3-hydrxypropanal as a substrate reveal lower activity of lr_0030 mutant extracts from exponential growing cells compared to wild type. During biotechnological 3-hydroxypropanal production using non-growing cells, the ratio 3-hydroxypropanal to 1,3-propanediol is approximately 7 in the wild type and lr_0030 mutant; growth behaviour on glucose is comparable between the wild type and a ORF lr1734 deletion mutant. On glucose + glycerol, the exponential growth rate of the wild type and the deletion mutant are similar. Glycerol addition results in decreased ethanol production both in the wild type and mutant. During biotechnological 3-hydroxypropanal production using non-growing cells, the ratio 3-hydroxypropanal to 1,3-propanediol is approximately 7 in the wild type, whereas this ratio is 12.5 in the mutant lacking lr_1734