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6.5.1.B3: 2'-5' RNA ligase (GTP-activated)

This is an abbreviated version!
For detailed information about 2'-5' RNA ligase (GTP-activated), go to the full flat file.

Word Map on EC 6.5.1.B3

Reaction

a 3'-half-tRNA molecule with a 5'-OH end
+
a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end
=
a mature tRNA molecule containing a 2'-5'-phosphodiester bond

Synonyms

GTP-dependent RNA ligase, PF0027, PH0099

ECTree

     6 Ligases
         6.5 Forming phosphoric-ester bonds
             6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
                6.5.1.B3 2'-5' RNA ligase (GTP-activated)

Crystallization

Crystallization on EC 6.5.1.B3 - 2'-5' RNA ligase (GTP-activated)

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
crystal structure solved at 1.94 A resolution, structural comparison wuth the 2',5' RNA ligase from Thermus thermophilus