6.5.1.B3: 2'-5' RNA ligase (GTP-activated)

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For detailed information about 2'-5' RNA ligase (GTP-activated), go to the full flat file.

Word Map on EC 6.5.1.B3

6.5.1.B3

byproduct

8-hydroxyoctanoic

arachidonic

e-cadherin

pyrococcus

cox-catalyzed

histone

procaspase

archaeon

safer

4-week

heat-stable

bxpc-3

intensified

four-week

gemcitabine

furiosus

anti-tumor

hyperthermophilic

desaturases

pro-apoptotic

transwell

cyclooxygenase-2

parp

2-series

delta-6

Reaction

a 3'-half-tRNA molecule with a 5'-OH end

+

a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end

=

a mature tRNA molecule containing a 2'-5'-phosphodiester bond

Synonyms

GTP-dependent RNA ligase, PF0027, PH0099

ECTree

6.5 Forming phosphoric-ester bonds

6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)

6.5.1.B3 2'-5' RNA ligase (GTP-activated)

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3	Organism
1	pH Optimum
1	Purification (Commentary)
3	Reaction
3	Reference
2	Substrates and Products (Substrate)
4	Synonyms
1	Temperature Optimum [°C]

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Cloned on EC 6.5.1.B3 - 2'-5' RNA ligase (GTP-activated)

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expression in Escherichia coli

Pyrococcus horikoshii

overexpression of recombinant C-terminal His-tagged protein

Pyrococcus furiosus

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Release 2023.1 (January 2023)