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6.5.1.B1: 2'-5' RNA ligase (NTP-independent)

This is an abbreviated version!
For detailed information about 2'-5' RNA ligase (NTP-independent), go to the full flat file.

Reaction

a 3'-half-tRNA molecule with a 5'-OH end
+
a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end
=
a mature tRNA molecule containing a 2'-5'-phosphodiester bond

ECTree

     6 Ligases
         6.5 Forming phosphoric-ester bonds
             6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
                6.5.1.B1 2'-5' RNA ligase (NTP-independent)

Reaction

Reaction on EC 6.5.1.B1 - 2'-5' RNA ligase (NTP-independent)

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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a 3'-half-tRNA molecule with a 5'-oH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end = a mature tRNA molecule containing a 2'-5'-phosphodiester bond
show the reaction diagram
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