6.5.1.B1: 2'-5' RNA ligase (NTP-independent)

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Reaction

ECTree

     6 Ligases

         6.5 Forming phosphoric-ester bonds

             6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)

                6.5.1.B1 2'-5' RNA ligase (NTP-independent)

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1	AA Sequence
1	Cloned(Commentary)
1	Cofactor
2	General Information
2	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
2	Organism
1	pH Optimum
1	Purification (Commentary)
1	Reaction
2	Reference
3	Substrates and Products (Substrate)
1	Temperature Optimum [°C]

Cloned

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Cloned on EC 6.5.1.B1 - 2'-5' RNA ligase (NTP-independent)

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

expression in Escherichia coli. Moderate overexpression of the ligase protein lead to slower growth rates and a temperature-sensitive phenotype in both wild-type and RNA ligase knockout strains

Escherichia coli

P37025

722602