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6.5.1.7: DNA ligase (ATP, ADP or GTP)

This is an abbreviated version!
For detailed information about DNA ligase (ATP, ADP or GTP), go to the full flat file.

Reaction

(deoxyribonucleotide)n-3'-hydroxyl
+
5'-(5'-diphosphoadenosine)-(deoxyribonucleotide)m
=
(deoxyribonucleotide)n+m
+
AMP

Synonyms

Hbu DNA ligase, multiple cofactor-dependent DNA ligase, Szi DNA ligase

ECTree

     6 Ligases
         6.5 Forming phosphoric-ester bonds
             6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
                6.5.1.7 DNA ligase (ATP, ADP or GTP)

Reference

Reference on EC 6.5.1.7 - DNA ligase (ATP, ADP or GTP)

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sun, Y.; Seo, M.S.; Kim, J.H.; Kim, Y.J.; Kim, G.A.; Lee, J.I.; Lee, J.H.; Kwon, S.T.
Novel DNA ligase with broad nucleotide cofactor specificity from the hyperthermophilic crenarchaeon Sulfophobococcus zilligii: influence of ancestral DNA ligase on cofactor utilization
Environ. Microbiol.
10
3212-3224
2008
Sulfophobococcus zilligii, Sulfophobococcus zilligii DSM Z 11193
Manually annotated by BRENDA team
Supangat, S.; An, Y.J.; Sun, Y.; Kwon, S.T.; Cha, S.S.
Purification, crystallization and preliminary crystallographic analysis of a multiple cofactor-dependent DNA ligase from Sulfophobococcus zilligii
Acta Crystallogr. Sect. F
66
1583-1585
2010
Sulfophobococcus zilligii
Manually annotated by BRENDA team
Kim, J.H.; Lee, K.K.; Sun, Y.; Seo, G.J.; Cho, S.S.; Kwon, S.H.; Kwon, S.T.
Broad nucleotide cofactor specificity of DNA ligase from the hyperthermophilic crenarchaeon Hyperthermus butylicus and its evolutionary significance
Extremophiles
17
515-522
2013
Hyperthermus butylicus, Hyperthermus butylicus DSM Z 5456
Manually annotated by BRENDA team