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6.5.1.7: DNA ligase (ATP, ADP or GTP)

This is an abbreviated version!
For detailed information about DNA ligase (ATP, ADP or GTP), go to the full flat file.

Reaction

(deoxyribonucleotide)n-3'-hydroxyl
+
5'-(5'-diphosphoadenosine)-(deoxyribonucleotide)m
=
(deoxyribonucleotide)n+m
+
AMP

Synonyms

Hbu DNA ligase, multiple cofactor-dependent DNA ligase, Szi DNA ligase

ECTree

     6 Ligases
         6.5 Forming phosphoric-ester bonds
             6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
                6.5.1.7 DNA ligase (ATP, ADP or GTP)

Natural Substrates Products

Natural Substrates Products on EC 6.5.1.7 - DNA ligase (ATP, ADP or GTP)

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ADP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
AMP + phosphate + (deoxyribonucleotide)n+m
show the reaction diagram
ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
AMP + diphosphate + (deoxyribonucleotide)n+m
show the reaction diagram
GTP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
GMP + diphosphate + (deoxyribonucleotide)n+m
show the reaction diagram