6.5.1.5: RNA 3'-terminal-phosphate cyclase (GTP)

This is an abbreviated version!
For detailed information about RNA 3'-terminal-phosphate cyclase (GTP), go to the full flat file.

Reaction

Synonyms

Pf-Rtc, PF1549

ECTree

     6 Ligases

         6.5 Forming phosphoric-ester bonds

             6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)

                6.5.1.5 RNA 3'-terminal-phosphate cyclase (GTP)

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
2	AA Sequence
1	Cloned(Commentary)
1	General Information
1	Inhibitors
2	Metals/Ions
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
1	Organism
1	pH Optimum
1	Purification (Commentary)
4	Reaction
1	Reference
2	Substrates and Products (Substrate)
1	Subunits
2	Synonyms
1	Systematic Name
1	Temperature Range [°C]

Substrates Products

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Substrates Products on EC 6.5.1.5 - RNA 3'-terminal-phosphate cyclase (GTP)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Substrate/Product Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

GTP + RNA 3'-terminal-phosphate

GMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate

2 entries

GTP + RNA 3'-terminal-phosphate

GMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate

Pyrococcus furiosus

Q8U0N7

the enzyme may contribute to GTP-dependent RNA ligation activity through the 2'-5' RNA ligase

722334

-

-

?

GTP + RNA 3'-terminal-phosphate

GMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate

Pyrococcus furiosus

Q8U0N7

the enzyme utilizes GTP approximately 10times more effectively than ATP. UTP and CTP have no effect on activity. Oligoribonucleotide substrates of different lengths (4-, 8- and 12-mers) are tested, the 4-mer is the most efficient substrate

722334

-

-

?