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6.5.1.3: RNA ligase (ATP)

This is an abbreviated version!
For detailed information about RNA ligase (ATP), go to the full flat file.

Word Map on EC 6.5.1.3

Reaction

(ribonucleotide)n-3'-hydroxyl
+
5'-(5'-diphosphoadenosine)-(ribonucleotide)m
=
(ribonucleotide)n+m
+
AMP

Synonyms

ATP-dependent RNA ligase, b1-10t, bacteriophage RNA ligase, band IV protein, class I ligase, class I RNA ligase ribozyme, DraRnI, DraRnl, DREL, gp24.1, P52, phage Rnl2, Polynucleotide synthetase, Polyribonucleotide ligase, Polyribonucleotide synthase (ATP), REL1, Ribonucleic ligase, ribonucleprotein editing complex, RM378 RNA ligase, RNA editing ligase 1, RNA ligase, RNA ligase (ATP), RNA ligase 1, RNA ligase 2, RNA ligase ribozyme, RNA-editing ligase 1, RNL, Rnl1, Rnl2, Rnl5, RnlA, RtcA, rtcB, Synthetase, polyribonucleotide, T4 RNA ligase, T4 RNA ligase 1, T4 RNA ligase 2, T4Rnl2, TbMP52, TbREL1, thermostable RNA ligase 1, Trl1

ECTree

     6 Ligases
         6.5 Forming phosphoric-ester bonds
             6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
                6.5.1.3 RNA ligase (ATP)

IC50 Value

IC50 Value on EC 6.5.1.3 - RNA ligase (ATP)

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.00216
4-hydroxy-3-[(E)-(5-hydroxy-7-sulfonaphthalen-2-yl)diazenyl]-7-[(1-phenylethenyl)amino]naphthalene-2-sulfonic acid
Trypanosoma brucei
pH and temperature not specified in the publication
0.00159
6-hydroxy-5-[(E)-[3-[(E)-(2-hydroxynaphthalen-1-yl)diazenyl]-5-sulfophenyl]diazenyl]naphthalene-2-sulfonic acid
Trypanosoma brucei
pH and temperature not specified in the publication
0.00836
7,7'-iminobis(4-hydroxynaphthalene-2-sulfonic acid)
Trypanosoma brucei
pH and temperature not specified in the publication
0.00153
7-amino-4-hydroxy-3-[(E)-(5-hydroxy-7-sulfonaphthalen-2-yl)diazenyl]naphthalene-2-sulfonic acid
Trypanosoma brucei
pH and temperature not specified in the publication