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6.5.1.3: RNA ligase (ATP)

This is an abbreviated version!
For detailed information about RNA ligase (ATP), go to the full flat file.

Word Map on EC 6.5.1.3

Reaction

(ribonucleotide)n-3'-hydroxyl
+
5'-(5'-diphosphoadenosine)-(ribonucleotide)m
=
(ribonucleotide)n+m
+
AMP

Synonyms

ATP-dependent RNA ligase, b1-10t, bacteriophage RNA ligase, band IV protein, class I ligase, class I RNA ligase ribozyme, DraRnI, DraRnl, DREL, gp24.1, P52, phage Rnl2, Polynucleotide synthetase, Polyribonucleotide ligase, Polyribonucleotide synthase (ATP), REL1, Ribonucleic ligase, ribonucleprotein editing complex, RM378 RNA ligase, RNA editing ligase 1, RNA ligase, RNA ligase (ATP), RNA ligase 1, RNA ligase 2, RNA ligase ribozyme, RNA-editing ligase 1, RNL, Rnl1, Rnl2, Rnl5, RnlA, RtcA, rtcB, Synthetase, polyribonucleotide, T4 RNA ligase, T4 RNA ligase 1, T4 RNA ligase 2, T4Rnl2, TbMP52, TbREL1, thermostable RNA ligase 1, Trl1

ECTree

     6 Ligases
         6.5 Forming phosphoric-ester bonds
             6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
                6.5.1.3 RNA ligase (ATP)

Disease

Disease on EC 6.5.1.3 - RNA ligase (ATP)

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acquired Immunodeficiency Syndrome
Mutational analysis defines the 5'-kinase and 3'-phosphatase active sites of T4 polynucleotide kinase.
Breast Neoplasms
Protein Aggregation Patterns Inform about Breast Cancer Response to Antiestrogens and Reveal the RNA Ligase RTCB as Mediator of Acquired Tamoxifen Resistance.
Infections
Bacteriophage T4 RNA ligase is gene 63 product, the protein that promotes tail fiber attachment to the baseplate.
Bacteriophage T4 RNA ligase: preparation of a physically homogeneous, nuclease-free enzyme from hyperproducing infected cells.
Bacteriophage T4-induced anticodon-loop nuclease detected in a host strain restrictive to RNA ligase mutants.
Host transfer RNA cleavage and reunion in T4-infected Escherichia coli CTr5x.
In vitro reconstitution of anticodon nuclease from components encoded by phage T4 and Escherichia coli CTr5X.
Phage and host genetic determinants of the specific anticodon loop cleavages in bacteriophage T4-infected Escherichia coli CTr5X.
RNA ligase reaction products in plasmolyzed Escherichia coli cells infected by T4 bacteriophage.
Structure of a tRNA repair enzyme and molecular biology workhorse: T4 polynucleotide kinase.
Influenza, Human
CrystalDock: a novel approach to fragment-based drug design.
Rapid method for the characterization of 3' and 5' UTRs of influenza viruses.
Stomach Neoplasms
Two-stage cyclic enzymatic amplification method for ultrasensitive electrochemical assay of microRNA-21 in the blood serum of gastric cancer patients.
Trypanosomiasis, African
CrystalDock: a novel approach to fragment-based drug design.
Designing novel inhibitors of Trypanosoma brucei.
Functional and Structural Insights Revealed by Molecular Dynamics Simulations of an Essential RNA Editing Ligase in Trypanosoma brucei.
POVME 2.0: An Enhanced Tool for Determining Pocket Shape and Volume Characteristics.
Vesicular Stomatitis
Nucleotide sequence homology at the 3' termini of RNA from vesicular stomatitis virus and its defective interfering particles.
The complete sequence of a unique RNA species synthesized by a DI particle of VSV.
Virus Diseases
The C-terminal domain of T4 RNA ligase 1 confers specificity for tRNA repair.