6.5.1.2: DNA ligase (NAD+)

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For detailed information about DNA ligase (NAD+), go to the full flat file.

Word Map on EC 6.5.1.2

6.5.1.2

ligases

nick

medicine

nick-closing

helix-hairpin-helix

filiformis

analysis

synthesis

biotechnology

Reaction

5'-(5'-diphosphoadenosine)-(deoxyribonucleotide)m

Synonyms

beta-NAD+ -dependent DNA ligase, beta-NAD+-dependent DNA ligase, Deoxyribonucleate ligase, Deoxyribonucleic acid joinase, Deoxyribonucleic acid ligase, Deoxyribonucleic joinase, Deoxyribonucleic ligase, Deoxyribonucleic repair enzyme, Deoxyribonucleic-joining enzyme, DNA joinase, DNA ligase, DNA ligase (NAD), DNA repair enzyme, DNA-joining enzyme, LigA, Ligase, polynucleotide (nicotinamide adenine dinucleotide), LigN, MimiLIG, MsEPV DNA ligase, MtuLigA, NAD(+)-dependent DNA ligase, NAD+ dependent DNA ligase, NAD+ DNA ligase, NAD+-dependent DNA ligase, NAD+-dependent DNA ligase A, NAD-dependent DNA ligase, NDL, Polydeoxyribonucleotide synthase (NAD+), Polydeoxyribonucleotide synthase [NAD+], Polynucleotide ligase, Polynucleotide synthetase, Polynucleotide synthetase (nicotinamide adenine dinucleotide), Rv3014c, Synthetase, polydeoxyribonucleotide (nicotinamide adenine dinucleotide), T4 DNA ligase, Taq DNA ligase, Tfi DNA ligase, Tth DNA ligase, wBm-LigA

ECTree

6 Ligases

6.5 Forming phosphoric-ester bonds

6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)

6.5.1.2 DNA ligase (NAD+)

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Results	in table
16	Activating Compound
48846	AA Sequence
22	Application
1	CAS Registry Number
51	Cloned(Commentary)
120	Cofactor
13	Crystallization (Commentary)
1	Expression
3	General Information
1	General Stability
449	IC50 Value
614	Inhibitors
7	Ki Value [mM]
38	KM Value [mM]
85	Metals/Ions
27	Molecular Weight [Da]
112	Natural Substrates/ Products (Substrates)
877	Organism
56	PDB ID
20	pH Optimum
8	pH Range
1	pH Stability
183	Protein Variants
51	Purification (Commentary)
32	Reaction
1	Reaction Type
193	Reference
5	Specific Activity [micromol/min/mg]
5	Storage Stability
245	Substrates and Products (Substrate)
13	Subunits
249	Synonyms
1	Systematic Name
24	Temperature Optimum [°C]
10	Temperature Range [°C]
16	Temperature Stability [°C]
15	Turnover Number [1/s]

Synonyms

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Synonyms on EC 6.5.1.2 - DNA ligase (NAD+)

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beta-NAD+ -dependent DNA ligase

5 entries

beta-NAD+-dependent DNA ligase

Mycoplasma pneumoniae

747327

Deoxyribonucleate ligase

Deoxyribonucleic acid joinase

Deoxyribonucleic acid ligase

Deoxyribonucleic joinase

Deoxyribonucleic ligase

Deoxyribonucleic repair enzyme

Deoxyribonucleic-joining enzyme

DNA joinase

DNA ligase

4 entries

DNA ligase (NAD)

DNA repair enzyme

DNA-joining enzyme

LigA

39 entries

Ligase, polynucleotide (nicotinamide adenine dinucleotide)

LigN

Haloferax volcanii

672808, 676060, 747798

MimiLIG

Mimivirus

677247

MsEPV DNA ligase

Melanoplus sanguinipes

661248

MtuLigA

3 entries

NAD(+)-dependent DNA ligase

4 entries

NAD+ dependent DNA ligase

Mycobacterium tuberculosis

710492

NAD+ DNA ligase

2 entries

NAD+-dependent DNA ligase

33 entries

NAD+-dependent DNA ligase A

2 entries

NAD-dependent DNA ligase

36 entries

NDL

6 entries

Polydeoxyribonucleotide synthase (NAD+)

Polydeoxyribonucleotide synthase [NAD+]

Polynucleotide ligase

Polynucleotide synthetase

Polynucleotide synthetase (nicotinamide adenine dinucleotide)

Rv3014c

2 entries

Synthetase, polydeoxyribonucleotide (nicotinamide adenine dinucleotide)

T4 DNA ligase

Tequatrovirus T4

708959

Taq DNA ligase

Thermus aquaticus

708959

Tfi DNA ligase

Tth DNA ligase

wBm-LigA

Wolbachia endosymbiont of Brugia malayi

728580