6.4.1.7: 2-oxoglutarate carboxylase

This is an abbreviated version!
For detailed information about 2-oxoglutarate carboxylase, go to the full flat file.

Reaction

Synonyms

carboxylating factor for ICDH, CFI, OGC, oxalosuccinate synthetase

ECTree

     6 Ligases

         6.4 Forming carbon-carbon bonds

             6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)

                6.4.1.7 2-oxoglutarate carboxylase

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Results	in table
689	AA Sequence
2	Cloned(Commentary)
2	Cofactor
1	Inhibitors
2	KM Value [mM]
1	Localization
1	Metals/Ions
3	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
29	Organism
1	Pathway
6	PDB ID
1	pH Optimum
1	pI Value
2	Purification (Commentary)
1	Reaction
5	Reference
1	Source Tissue
1	Storage Stability
7	Substrates and Products (Substrate)
2	Subunits
8	Synonyms
1	Temperature Optimum [°C]
1	Temperature Stability [°C]
2	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 6.4.1.7 - 2-oxoglutarate carboxylase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

ATP + 2-oxoglutarate + HCO3-

ADP + phosphate + oxalosuccinate

5 entries

ATP + 2-oxoglutarate + HCO3-

ADP + phosphate + oxalosuccinate

Hydrogenobacter thermophilus

-

-

670306, 670325

-

-

?

ATP + 2-oxoglutarate + HCO3-

ADP + phosphate + oxalosuccinate

Hydrogenobacter thermophilus

-

first step of the reductive carboxylation from 2-oxoglutarate to isocitrate. Oxalosuccinate, the product of the reaction is unstable and is quickly converted into isocitrate by the action of EC 1.1.1.41

670325

-

-

?

ATP + 2-oxoglutarate + HCO3-

ADP + phosphate + oxalosuccinate

Hydrogenobacter thermophilus TK-6 / IAM 12695

-

-

670306, 670325

-

-

?

ATP + 2-oxoglutarate + HCO3-

ADP + phosphate + oxalosuccinate

Hydrogenobacter thermophilus TK-6 / IAM 12695

-

first step of the reductive carboxylation from 2-oxoglutarate to isocitrate. Oxalosuccinate, the product of the reaction is unstable and is quickly converted into isocitrate by the action of EC 1.1.1.41

670325

-

-

?

ATP + 2-oxoglutarate + HCO3-

ADP + phosphate + oxalosuccinate

Rattus norvegicus

-

-

667453

-

-

?