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6.4.1.7: 2-oxoglutarate carboxylase

This is an abbreviated version!
For detailed information about 2-oxoglutarate carboxylase, go to the full flat file.

Reaction

ATP
+
2-oxoglutarate
+
HCO3-
=
ADP
+
phosphate
+
oxalosuccinate

Synonyms

carboxylating factor for ICDH, CFI, OGC, oxalosuccinate synthetase

ECTree

     6 Ligases
         6.4 Forming carbon-carbon bonds
             6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
                6.4.1.7 2-oxoglutarate carboxylase

Reference

Reference on EC 6.4.1.7 - 2-oxoglutarate carboxylase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Keech, D.B.; Mattoo, A.K.; Carabott, M.J.J.; Wallace, J.C.
The ATP-dependent reductive carboxylation of 2-oxoglutarate using cytosol from rat liver
Biochem. Biophys. Res. Commun.
71
712-718
1976
Rattus norvegicus
Manually annotated by BRENDA team
Aoshima, M.; Ishii, M.; Igarashi, Y.
A novel biotin protein required for reductive carboxylation of 2-oxoglutarate by isocitrate dehydrogenase in Hydrogenobacter thermophilus TK-6
Mol. Microbiol.
51
791-798
2004
Hydrogenobacter thermophilus, Hydrogenobacter thermophilus TK-6 / IAM 12695
Manually annotated by BRENDA team
Aoshima, M.; Igarashi, Y.
A novel oxalosuccinate-forming enzyme involved in the reductive carboxylation of 2-oxoglutarate in Hydrogenobacter thermophilus TK-6
Mol. Microbiol.
62
748-759
2006
Hydrogenobacter thermophilus, Hydrogenobacter thermophilus TK-6 / IAM 12695
Manually annotated by BRENDA team