6.4.1.6: acetone carboxylase

This is an abbreviated version!
For detailed information about acetone carboxylase, go to the full flat file.

+ 2 H2O =

+ 2 phosphate

acetone carboxylase, acetone-carboxylating enzyme, ACX, AcxA, AcxB, AcxC, Alide_1502, Alide_1503, Alide_1504, carboxylase, acetone

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Results	in table
4	Activating Compound
653	AA Sequence
1	Application
1	CAS Registry Number
8	Cofactor
1	Crystallization (Commentary)
3	Expression
2	General Information
1	General Stability
4	Inhibitors
7	KM Value [mM]
23	Metals/Ions
30	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
28	Organism
1	Oxidation Stability
3	Pathway
24	PDB ID
4	pH Optimum
1	pH Range
1	Protein Variants
8	Purification (Commentary)
4	Reaction
1	Reaction Type
22	Reference
2	Source Tissue
11	Specific Activity [micromol/min/mg]
2	Storage Stability
37	Substrates and Products (Substrate)
8	Subunits
13	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
1	Turnover Number [1/s]

Substrates Products on EC 6.4.1.6 - acetone carboxylase

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2-butanone + CO2 + ATP + H2O

2-methyl-3-oxobutanoate + AMP + phosphate

acetone + CO2 + ATP + H2O

acetoacetate + AMP + phosphate

acetone + CO2 + GTP + H2O

acetoacetate + GMP + phosphate

better activity than with ATP

butanone + CO2 + ATP + H2O

3-oxopentanoate + AMP + phosphate

additional information