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6.4.1.3: propionyl-CoA carboxylase

This is an abbreviated version!
For detailed information about propionyl-CoA carboxylase, go to the full flat file.

Word Map on EC 6.4.1.3

Reaction

ATP
+
propanoyl-CoA
 +
HCO3-
 +
H+
=
ADP
 +
phosphate
 +
(S)-methylmalonyl-CoA

Synonyms

AccA3-PccB complex, acetyl-CoA/propionyl-CoA carboxylase, Carboxylase, propional coenzyme A (adenosine triphosphate-hydrolyzing), LA_2736-LA_2735, Pcase, PCC, PccA, PccA-1, PCCase, PccB, PccB-1, pccBC, PccE, Propanoyl-CoA:carbon dioxide ligase, Propionyl coenzyme A carboxylase, Propionyl coenzyme A carboxylase (adenosine triphosphate-hydrolyzing), Propionyl coenzyme A carboxylase (ATP-hydrolyzing), Propionyl-CoA carboxylase, propionyl-coenzyme A carboxylase

ECTree

     6 Ligases
         6.4 Forming carbon-carbon bonds
             6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
                6.4.1.3 propionyl-CoA carboxylase

Specific Activity

Specific Activity on EC 6.4.1.3 - propionyl-CoA carboxylase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.00186
-
cell culture
0.00199
-
cell culture
0.00442
-
cell culture
0.00483
-
cell culture
0.00535
-
cell culture
0.00673
-
cell culture
0.01177
-
cell culture
0.0248
-
cell culture
11.9
Q877I4; Q877I3; Q877I5
pH 7.5, 70°C, propionyl-CoA carboxylase activity
14.13
-
purified enzyme, pH 7.2, 30°C
23.35
-
purified wild-type enzyme
27.7
-
-
3.3
-
purified enzyme, pH 7.5, 65°C
32.34
-
purified mutant enzyme A497V
5.6
-
-
7.54
-
purified mutant enzyme E168K
9.93
-
purified mutant enzyme R165W
9.95
-
purified mutant enzyme R410W
additional information
-
-