6.4.1.3: propionyl-CoA carboxylase

This is an abbreviated version!
For detailed information about propionyl-CoA carboxylase, go to the full flat file.

Word Map on EC 6.4.1.3

6.4.1.3

propionic

acidemia

biotin-dependent

carboxylases

methylmalonyl-coa

acidosis

methylmalonic

3-hydroxypropionate

methylcitrate

propionylation

hyperammonemia

holocarboxylase

3-methylcrotonyl-coa

acidurias

biotin-containing

carboxyltransferase

biotin-deficient

hyperglycinemia

beta-methylcrotonyl-coa

biotin-binding

odd-chain

anaplerosis

transcarboxylase

3-hydroxyisovaleric

propionylcarnitine

synthesis

analysis

medicine

apocarboxylases

biotinidase

Reaction

Synonyms

AccA3-PccB complex, acetyl-CoA/propionyl-CoA carboxylase, Carboxylase, propional coenzyme A (adenosine triphosphate-hydrolyzing), LA_2736-LA_2735, Pcase, PCC, PccA, PccA-1, PCCase, PccB, PccB-1, pccBC, PccE, Propanoyl-CoA:carbon dioxide ligase, Propionyl coenzyme A carboxylase, Propionyl coenzyme A carboxylase (adenosine triphosphate-hydrolyzing), Propionyl coenzyme A carboxylase (ATP-hydrolyzing), Propionyl-CoA carboxylase, propionyl-coenzyme A carboxylase

ECTree

6 Ligases

6.4 Forming carbon-carbon bonds

6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)

6.4.1.3 propionyl-CoA carboxylase

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Results	in table
7	Activating Compound
10065	AA Sequence
6	Application
1	CAS Registry Number
24	Cloned(Commentary)
35	Cofactor
5	Crystallization (Commentary)
359	Disease/ Diagnostics
1	Expression
7	General Information
2	General Stability
35	Inhibitors
6	kcat/KM [mM/s]
50	KM Value [mM]
10	Localization
16	Metals/Ions
39	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
218	Organism
19	Pathway
101	PDB ID
8	pH Optimum
2	pH Range
3	pH Stability
72	Protein Variants
19	Purification (Commentary)
1	Reaction
1	Reaction Type
90	Reference
49	Source Tissue
23	Specific Activity [micromol/min/mg]
1	Storage Stability
135	Substrates and Products (Substrate)
27	Subunits
75	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
2	Temperature Range [°C]
12	Temperature Stability [°C]
7	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 6.4.1.3 - propionyl-CoA carboxylase

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(NH4)2SO4

Pseudomonas citronellolis

1871

ADP

Metallosphaera sedula

weak inhibition

651169

ATP

Acidianus brierleyi

Q877I4; Q877I3; Q877I5

above 2.0 mM

725234

CaCl2