6.4.1.1: pyruvate carboxylase

This is an abbreviated version!
For detailed information about pyruvate carboxylase, go to the full flat file.

Word Map on EC 6.4.1.1

6.4.1.1

phosphoenolpyruvate

gluconeogenesis

carboxykinase

biotin

oxaloacetate

acetyl-coa

tricarboxylic

gluconeogenic

anaplerotic

malate

citrate

tca

co2

malic

pepck

carboxylases

astrocyte

glucose-6-phosphatase

biotin-dependent

acidosis

propionyl-coa

citric

krebs

glutamicum

bark

pine

biotin-containing

13c-labeled

propionyl

isotopomer

maritime

1-13cglucose

avidin

hyperammonemia

fructose-1,6-diphosphatase

carboxyltransferase

pyrogenic

4.1.1.32

1,6-bisphosphatase

holocarboxylase

transcarboxylase

biotinidase

pyrolytic

leigh

ureagenesis

medicine

glucogenic

biotechnology

penicillinase

13c-enriched

pinaster

synthesis

3-methylcrotonyl-coa

Reaction

ATP

+

pyruvate

+

HCO3-

+

H+

=

ADP

+

phosphate

+

oxaloacetate

Synonyms

Carboxylase, pyruvate, EhPYC1, HpPyc1p, Mfla_1512, MSmeg_2412, PC, Pcase, PCB, PCC, PCx, PYC, Pyc1, Pyc1p, PYC2, pycA, pyruvate carboxylase, pyruvate carboxylase 1, Pyruvic carboxylase, RePC

ECTree

6.4 Forming carbon-carbon bonds

6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)

6.4.1.1 pyruvate carboxylase

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Results	in table
84	Activating Compound
17340	AA Sequence
14	Application
1	CAS Registry Number
63	Cloned(Commentary)
82	Cofactor
13	Crystallization (Commentary)
1260	Disease/ Diagnostics
1	Expression
11	General Information
13	General Stability
1	IC50 Value
119	Inhibitors
23	kcat/KM [mM/s]
14	Ki Value [mM]
127	KM Value [mM]
32	Localization
86	Metals/Ions
67	Molecular Weight [Da]
81	Natural Substrates/ Products (Substrates)
246	Organism
13	Pathway
83	PDB ID
22	pH Optimum
3	pH Range
1	Posttranslational Modification
111	Protein Variants
43	Purification (Commentary)
25	Reaction
55	Reaction Type
196	Reference
112	Source Tissue
37	Specific Activity [micromol/min/mg]
9	Storage Stability
231	Substrates and Products (Substrate)
80	Subunits
57	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
1	Temperature Range [°C]
13	Temperature Stability [°C]
67	Turnover Number [1/s]

Organism

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Organism on EC 6.4.1.1 - pyruvate carboxylase

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-

-

-

Manually annotated by BRENDA team

-

-

-

Manually annotated by BRENDA team

Aquifex aeolicus

-

-

-

Manually annotated by BRENDA team

Arthrobacter globiformis

-

-

-

Manually annotated by BRENDA team

Aspergillus nidulans

-

1763, 1765, 1792

-

-

Manually annotated by BRENDA team

Aspergillus terreus

-

-

-

Manually annotated by BRENDA team

Aspergillus terreus Nrrl 1960

-

-

-

Manually annotated by BRENDA team

Bacillus licheniformis

-

-

-

Manually annotated by BRENDA team

Bacillus sp. (in: Bacteria)

thermophilic

1761, 1767, 1769

-

-

Manually annotated by BRENDA team

Bacillus subtilis

-

-

-

Manually annotated by BRENDA team

show

Caenorhabditis elegans

-

SwissProt

Manually annotated by BRENDA team

Corynebacterium glutamicum

-

1801, 649374, 652964

-

-

Manually annotated by BRENDA team

Emiliania huxleyi

-

UniProt

Manually annotated by BRENDA team

Escherichia coli

-

-

-

Manually annotated by BRENDA team

-

1769, 1773, 1776, 1781, 1785, 1786, 1787, 1789, 1790, 1792, 1795, 1797, 649461, 649995

-

-

Manually annotated by BRENDA team

Geobacillus stearothermophilus

-

-

-

Manually annotated by BRENDA team

Geobacillus thermodenitrificans

-

651171, 661137, 663285, 690828, 692637

-

-

Manually annotated by BRENDA team

show

Komagataella pastoris

-

-

-

Manually annotated by BRENDA team

Lactococcus lactis

-

660777, 661386, 661388, 746323

-

-

Manually annotated by BRENDA team

Leptosphaeria michotii

-

-

-

Manually annotated by BRENDA team

Listeria monocytogenes

-

-

-

Manually annotated by BRENDA team

Listeria monocytogenes Sv1/2a EGD-e

-

-

-

Manually annotated by BRENDA team

-

-

-

Manually annotated by BRENDA team

Meleagris gallopavo

-

-

-

Manually annotated by BRENDA team

Methanobacterium sp.

-

-

-

Manually annotated by BRENDA team

Methanocaldococcus jannaschii

-

-

-

Manually annotated by BRENDA team

Methanococcus sp.

-

-

-

Manually annotated by BRENDA team

Methanosarcina sp.

-

-

-

Manually annotated by BRENDA team

Methanothermobacter thermautotrophicus

-

-

-

Manually annotated by BRENDA team

Methanothermobacter thermautotrophicus DELTAH

-

-

-

Manually annotated by BRENDA team

Methylobacillus flagellatus

-

UniProt

Manually annotated by BRENDA team

Methylobacillus flagellatus DSM 6875

-

UniProt

Manually annotated by BRENDA team

show

Mycolicibacterium smegmatis

show

Mycolicibacterium smegmatis ATCC 700084

-

UniProt

Manually annotated by BRENDA team

Ogataea angusta

show

Ogataea angusta ass3

ass3

-

-

Manually annotated by BRENDA team

-

-

-

Manually annotated by BRENDA team

-

-

-

Manually annotated by BRENDA team

Phycomyces blakesleeanus

-

-

-

Manually annotated by BRENDA team

Pseudomonas aeruginosa

show

Pseudomonas aeruginosa P4

soil-isolate

-

-

Manually annotated by BRENDA team

Pseudomonas citronellolis

-

1764, 1773, 1792

-

-

Manually annotated by BRENDA team

Pseudomonas fluorescens

show

Pseudomonas sp.

-

-

-

Manually annotated by BRENDA team

Rattus norvegicus

show

show

Rhizobium etli ATCC 51251

-

744159, 744329, 744354, 744355, 744903

UniProt

Manually annotated by BRENDA team

Rhizobium etli CFN 42

-

726972, 727004, 727040

UniProt

Manually annotated by BRENDA team

Rhizopus arrhizus

-

-

-

Manually annotated by BRENDA team

Rhodobacter capsulatus

overexpressing strain

-

-

Manually annotated by BRENDA team

Roseobacter denitrificans OCh 114

-

-

-

Manually annotated by BRENDA team

Saccharomyces cerevisiae

show

Saccharomyces cerevisiae DM18

-

SwissProt

Manually annotated by BRENDA team

Schistocerca gregaria

-

-

-

Manually annotated by BRENDA team

Sinorhizobium meliloti

Rm1021

-

-

Manually annotated by BRENDA team

Sinorhizobium meliloti Rm1021

Rm1021

-

-

Manually annotated by BRENDA team

Staphylococcus aureus

show

Staphylococcus aureus ATCC 700699

-

UniProt

Manually annotated by BRENDA team

Starkeya novella

-

-

-

Manually annotated by BRENDA team

-

-

-

Manually annotated by BRENDA team

Tenebrio molitor

-

-

-

Manually annotated by BRENDA team

Thiobacillus sp.

A2

-

-

Manually annotated by BRENDA team

Thiobacillus sp. A2

A2

-

-

Manually annotated by BRENDA team

-

-

-

Manually annotated by BRENDA team

Weizmannia coagulans

-

-

-

Manually annotated by BRENDA team

Yarrowia lipolytica

-

-

-

Manually annotated by BRENDA team

[Bacillus] caldotenax

-

-

-

Manually annotated by BRENDA team

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Release 2023.1 (January 2023)