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6.3.5.7: glutaminyl-tRNA synthase (glutamine-hydrolysing)

This is an abbreviated version!
For detailed information about glutaminyl-tRNA synthase (glutamine-hydrolysing), go to the full flat file.

Word Map on EC 6.3.5.7

Reaction

5-phosphooxy-L-glutamyl-tRNAGln
+
NH3
=
L-glutaminyl-tRNAGln
+
phosphate

Synonyms

aa-tRNA amidotransferase, AdT, amidotransferase B, amidotransferase C, amidotransferase, glutamyl-transfer ribonucleate (glutamine-specific), aminoacyl-tRNA amidotransferase, BANKA_112750, gatA, GatB, GatCAB, GatCAB amidotransferase, GatDE, Gln4, GlnRS, Glu-AdT, Glu-amidotransferase, Glu-tRNAGln amidotransferase, Glu-tRNAGlnAT, GluAdT GatDE, GluRS, glutamyl-tRNA(Gln) amidotransferase, glutamyl-tRNAGln amidotransferase, nondiscriminating GluRS, PBANKA_071810, PF3D7_0416100, PF3D7_0628800, Qrsl1

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
                6.3.5.7 glutaminyl-tRNA synthase (glutamine-hydrolysing)

Crystallization

Crystallization on EC 6.3.5.7 - glutaminyl-tRNA synthase (glutamine-hydrolysing)

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
to 3.3 A resolution
-
reaction involves the intramolecular transfer of ammonia between two spatially separated active sites, molecular dynamics simulations on wild-type and mutant structures to investigate the transport of ammonia along two putative tunnels
the glutamine transamidosome complex consisting of tRNAGln, glutamyltRNA synthase (GluRS) and the heterotrimeric amidotransferase GatCAB is crystalyzed at 3.35 A. Crystals are grown by the sitting-drop vapour-diffusion method at 20°C