6.3.5.3: phosphoribosylformylglycinamidine synthase

This is an abbreviated version!
For detailed information about phosphoribosylformylglycinamidine synthase, go to the full flat file.

Word Map on EC 6.3.5.3

6.3.5.3

purine

glutaminase

tegument

gammaherpesvirus

amidophosphoribosyltransferase

aminoimidazole

purinosome

acivicin

medicine

Reaction

N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide

2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine

Synonyms

2-Formamido-N-ribosylacetamide 5'-phosphate:L-glutamine amido-ligase (adenosine diphosphate), 5'-phosphoribosylformyl glycinamidine synthetase, FGAM, FGAM synthase, FGAM synthetase, FGAM-synthetase, FGAMS, FGAR amidotransferase, FGAR-AT, FGARAT, formylglycinamide ribonucleotide amidotransferase, formylglycinamide ribonucleotide amidotransferase complex, Formylglycinamide ribonucloetide amidotransferase, Formylglycinamide ribotide amidotransferase, Formylglycinamide ribotide synthetase, formylglycinamide synthetase, LT2, mPurL, ORF75c, PFAS, phosphoribosylformylglycinamidine synthase II, Phosphoribosylformylglycinamidine synthetase, Phosphoribosylformylglycineamidine synthetase, Pur4, PurL, PurS, smPurL, StPurL, Synthetase, phosphoribosylformylglycinamide, TmPurL

ECTree

6 Ligases

6.3 Forming carbon-nitrogen bonds

6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor

6.3.5.3 phosphoribosylformylglycinamidine synthase

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Results	in table
75581	AA Sequence
2	Application
1	CAS Registry Number
13	Cloned(Commentary)
1	Cofactor
12	Crystallization (Commentary)
40	Disease/ Diagnostics
2	General Information
3	General Stability
26	Inhibitors
21	KM Value [mM]
4	Localization
13	Metals/Ions
11	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
38	Organism
8	Pathway
42	PDB ID
5	pH Optimum
3	pH Range
1	pH Stability
12	Protein Variants
9	Purification (Commentary)
7	Reaction
2	Reaction Type
38	Reference
27	Source Tissue
6	Specific Activity [micromol/min/mg]
1	Storage Stability
42	Substrates and Products (Substrate)
4	Subunits
50	Synonyms
1	Systematic Name
2	Temperature Stability [°C]
2	Turnover Number [1/s]

Organism

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Organism on EC 6.3.5.3 - phosphoribosylformylglycinamidine synthase

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Arabidopsis thaliana

694724

Bacillus subtilis

1259, 653151, 661076, 661078

Escherichia coli

1413, 1670

Gallus gallus

1663, 1665, 1666, 1667

Homo sapiens

2 entries

Methanocaldococcus jannaschii

subunit PurS

743962

Q58988

UniProt

Methanocaldococcus jannaschii DSM 2661

subunit PurS

743962

Q58988

UniProt

Methanothermobacter thermautotrophicus

thermophilic archaeon

653851

Murine gammaherpesvirus-68

virion tegument protein ORF75c

UniProt

1667, 1668, 1669

Pigeon

Salmonella enterica subsp. enterica serovar Typhimurium

2 entries

Sulfurisphaera tokodaii

subunit PurS

743962

F9VNF4

UniProt

Sulfurisphaera tokodaii DSM 16993

subunit PurS

UniProt

subunit PurS

UniProt

Thermus thermophilus DSM 579

subunit PurS

743962

Q5SI58

UniProt