Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

6.3.5.3: phosphoribosylformylglycinamidine synthase

This is an abbreviated version!
For detailed information about phosphoribosylformylglycinamidine synthase, go to the full flat file.

Word Map on EC 6.3.5.3

Reaction

ATP
+
N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide
+
L-glutamine
+
H2O
=
ADP
+
phosphate
+
2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine
+
L-glutamate

Synonyms

2-Formamido-N-ribosylacetamide 5'-phosphate:L-glutamine amido-ligase (adenosine diphosphate), 5'-phosphoribosylformyl glycinamidine synthetase, FGAM, FGAM synthase, FGAM synthetase, FGAM-synthetase, FGAMS, FGAR amidotransferase, FGAR-AT, FGARAT, formylglycinamide ribonucleotide amidotransferase, formylglycinamide ribonucleotide amidotransferase complex, Formylglycinamide ribonucloetide amidotransferase, Formylglycinamide ribotide amidotransferase, Formylglycinamide ribotide synthetase, formylglycinamide synthetase, LT2, mPurL, ORF75c, PFAS, phosphoribosylformylglycinamidine synthase II, Phosphoribosylformylglycinamidine synthetase, Phosphoribosylformylglycineamidine synthetase, Pur4, PurL, PurS, smPurL, StPurL, Synthetase, phosphoribosylformylglycinamide, TmPurL

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
                6.3.5.3 phosphoribosylformylglycinamidine synthase

General Stability

General Stability on EC 6.3.5.3 - phosphoribosylformylglycinamidine synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
a combination of Gln, MgCl2, and KCl protects against thermal inactivation
-
K+ required for stabilization
-
loss of activity during freezing and thawing
-