6.3.4.5: argininosuccinate synthase

This is an abbreviated version!
For detailed information about argininosuccinate synthase, go to the full flat file.

Word Map on EC 6.3.4.5

6.3.4.5

ornithine

citrullinemia

arginase

ammonia

hyperammonemia

deiminase

transcarbamylase

l-arginine

pegylated

auxotrophic

adi-peg20

carbamyl

adult-onset

coma

argininosuccinase

carbamoylphosphate

carbamoyltransferase

citrin

tropoelastin

urea-cycle

consciousness

medicine

ureogenesis

elastogenesis

ornithine-urea

elastin-derived

jararaca

coinduction

bothrops

n-acetylglutamate

drug development

molecular biology

Reaction

Synonyms

ARGG, Arginine succinate synthetase, argininosuccinate synthase, argininosuccinate synthase 1, Argininosuccinate synthetase, Argininosuccinic acid synthetase, arininosuccinate synthetase, AS, ASS, ASS1, Citrulline--aspartate ligase, Citrulline-aspartate ligase, EAS, Elastin-binding protein, PyARG1, Synthetase, argininosuccinate, tAsS

ECTree

6 Ligases

6.3 Forming carbon-nitrogen bonds

6.3.4 Other carbon-nitrogen ligases

6.3.4.5 argininosuccinate synthase

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Results	in table
13	Activating Compound
41481	AA Sequence
17	Application
1	CAS Registry Number
16	Cloned(Commentary)
8	Cofactor
11	Crystallization (Commentary)
1371	Disease/ Diagnostics
14	Expression
25	General Information
3	General Stability
5	IC50 Value
54	Inhibitors
1	Ki Value [mM]
56	KM Value [mM]
15	Localization
10	Metals/Ions
38	Molecular Weight [Da]
44	Natural Substrates/ Products (Substrates)
188	Organism
13	Pathway
53	PDB ID
17	pH Optimum
2	pH Range
1	pI Value
3	Posttranslational Modification
30	Protein Variants
23	Purification (Commentary)
12	Reaction
1	Reaction Type
90	Reference
90	Source Tissue
36	Specific Activity [micromol/min/mg]
5	Storage Stability
109	Substrates and Products (Substrate)
27	Subunits
93	Synonyms
1	Systematic Name
11	Temperature Optimum [°C]
5	Temperature Stability [°C]

KM Value

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KM Value on EC 6.3.4.5 - argininosuccinate synthase

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0.022

AMP

2 entries

0.12

argininosuccinate

Rattus norvegicus

1576

0.017 - 4.3

Asp

7 entries

0.12 - 0.18

aspartate

3 entries

0.041 - 0.66

ATP

13 entries

0.02 - 190

citrulline

16 entries

0.016

diphosphate

2 entries

0.025 - 0.038

L-Asp

5 entries

0.026 - 0.03

L-citrulline

2 entries

4.5

threo-beta-hydroxy-L-Asp

Bos taurus

1574

0.88

threo-beta-methyl-L-Asp

Bos taurus

1574

additional information

2 entries