6.3.4.21: nicotinate phosphoribosyltransferase

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For detailed information about nicotinate phosphoribosyltransferase, go to the full flat file.

Reaction

Synonyms

EC 2.4.2.11, LOC_Os03g62110, More, NA phosphoribosyltransferase, NAPRT, NaPRT1, NAPRTase, niacin ribonucleotidase, nicotinate phosphoribosyltransferase, nicotinate phosphoribosyltransferases, nicotinate-nucleotide:pyrophosphate phospho-alpha-D-ribosyltransferase, nicotinic acid mononucleotide glycohydrolase, nicotinic acid mononucleotide pyrophosphorylase, nicotinic acid phosphoribosyltransferase, NPRTase, pncB

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.4 Other carbon-nitrogen ligases

                6.3.4.21 nicotinate phosphoribosyltransferase

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Results	in table
11	Activating Compound
35699	AA Sequence
1	Application
1	CAS Registry Number
13	Cloned(Commentary)
46	Cofactor
3	Crystallization (Commentary)
88	Disease/ Diagnostics
1	Expression
1	General Information
9	General Stability
1	IC50 Value
60	Inhibitors
4	kcat/KM [mM/s]
41	KM Value [mM]
5	Localization
31	Metals/Ions
22	Molecular Weight [Da]
19	Natural Substrates/ Products (Substrates)
49	Organism
7	Pathway
2	PDB ID
8	pH Optimum
5	pH Range
3	pH Stability
13	Protein Variants
17	Purification (Commentary)
5	Reaction
5	Reaction Type
42	Reference
54	Source Tissue
24	Specific Activity [micromol/min/mg]
8	Storage Stability
62	Substrates and Products (Substrate)
11	Subunits
57	Synonyms
1	Systematic Name
11	Temperature Optimum [°C]
3	Temperature Stability [°C]
5	Turnover Number [1/s]

Storage Stability

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Storage Stability on EC 6.3.4.21 - nicotinate phosphoribosyltransferase

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STORAGE STABILITY

ORGANISM

UNIPROT

LITERATURE

-12°C, partially purified enzyme preparation, t1/2: at least 3 months

Bos taurus

-

637749

-25°C, at least 1 month

Saccharomyces cerevisiae

-

637750

-70°C, t1/2: 3 months

Homo sapiens

-

637752

-70ºC, no significantly decreased activity for up to 3 years, no significantly decreased after 8 years

Homo sapiens

-

637762

4ºC, as 70% saturated ammonium sulfate suspensions in 200 mM phosphate buffer, pH 8, 10% glycerol and 5 mM DTT

Salmonella enterica subsp. enterica serovar Typhimurium

-

637759, 637760, 637761

t1/2: at least 2 months

Salmonella enterica subsp. enterica serovar Typhimurium

-

637761