Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

6.3.4.21: nicotinate phosphoribosyltransferase

This is an abbreviated version!
For detailed information about nicotinate phosphoribosyltransferase, go to the full flat file.

Word Map on EC 6.3.4.21

Reaction

nicotinate
+
5-phospho-alpha-D-ribose 1-diphosphate
+
ATP
+
H2O
=
beta-nicotinate D-ribonucleotide
+
diphosphate
+
ADP
+
phosphate

Synonyms

EC 2.4.2.11, LOC_Os03g62110, More, NA phosphoribosyltransferase, NAPRT, NaPRT1, NAPRTase, niacin ribonucleotidase, nicotinate phosphoribosyltransferase, nicotinate phosphoribosyltransferases, nicotinate-nucleotide:pyrophosphate phospho-alpha-D-ribosyltransferase, nicotinic acid mononucleotide glycohydrolase, nicotinic acid mononucleotide pyrophosphorylase, nicotinic acid phosphoribosyltransferase, NPRTase, pncB

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.4 Other carbon-nitrogen ligases
                6.3.4.21 nicotinate phosphoribosyltransferase

Specific Activity

Specific Activity on EC 6.3.4.21 - nicotinate phosphoribosyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0012
-
-
0.0169
+/-0.006 micromol/min/mg, with respect to nicotinic acid, in presence of 1 mM NAD+, 80 ng enzyme, 10-70 microM nicotinamide, 0.3 mM PRPP, 30 min, 37°C, TLC-based quantification
0.0186
+/-0.006 micromol/min/mg, with respect to nicotinic acid, 80 ng enzyme, 10-70 microM nicotinamide, 0.3 mM PRPP, 30 min, 37°C, TLC-based quantification
0.0226
+/-0.0016 micromol/min/mg, with respect to 5-phospho-alpha-D-ribose 1-diphosphate, in presence of 1 mM NAD+, 20 ng enzyme, 40 microM nicotinamide, 0.14-1 microM PRPP, 15 min, 37°C, TLC-based quantification
0.0236
+/-0.0015 micromol/min/mg, with respect to 5-phospho-alpha-D-ribose 1-diphosphate, 20 ng enzyme, 40 microM nicotinamide, 0.14-1 microM PRPP, 15 min, 37°C, TLC-based quantification
0.052
-
-
0.08
-
recombinant enzyme from Escherichia coli strain BA203, pH and temperature not specified in the publication
0.095
-
crude extract
0.74
-
recombinant enzyme from Escherichia coli strain BA204, pH and temperature not specified in the publication
10.54
12.24
-
recombinant enzyme from Escherichia coli strain BA207, pH and temperature not specified in the publication
160.5
-
DEAE-Sephadex fraction
17.31
-
recombinant enzyme from Escherichia coli strain BA206, pH and temperature not specified in the publication
18.74
recombinant enzyme from Escherichia coli strain BA016, pH and temperature not specified in the publication
23.72
-
recombinant enzyme from Escherichia coli strain BA207, pH and temperature not specified in the publication
421.2
-
Sephacryl fraction
457.3
-
phenyl-Sepharose fraction