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6.3.4.2: CTP synthase (glutamine hydrolysing)

This is an abbreviated version!
For detailed information about CTP synthase (glutamine hydrolysing), go to the full flat file.

Word Map on EC 6.3.4.2

Reaction

ATP
+
UTP
+
L-glutamine
=
ADP
+
phosphate
+
CTP
+
L-glutamate

Synonyms

CTP synthase, CTP synthase 1, CTP synthetase, CTP synthetase 1, CTPS, CTPS1, CTPS2, CTPsyn, CTS, cytidine 5'-triphosphate synthase, cytidine 5'-triphosphate synthetase, cytidine triphosphate synthetase, cytidine triphosphate synthetase 1, EcCTPS, pfCTP synthetase, PyrG, synthetase, cytidine triphosphate, URA7, uridine triphosphate aminase, UTP-ammonia ligase, UTP:ammonia ligase (ADP-forming)

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.4 Other carbon-nitrogen ligases
                6.3.4.2 CTP synthase (glutamine hydrolysing)

pH Optimum

pH Optimum on EC 6.3.4.2 - CTP synthase (glutamine hydrolysing)

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
10.3 - 10.4
-
ammonia-dependent activity,maximal activity with NH4+ is at least 20% greater than with glutamine
7 - 9
-
broad
7.5 - 9.3
-
glutamine-dependent activity
8 - 8.5
-
assay at
8.1
assay at
8.6
-
reaction with ammonia
8.6 - 8.9
-
reaction with glutamine
8.7
-
reaction with NH4+, glutamine-dependent reaction activated by Mg2+ or Mn2+