6.3.4.2: CTP synthase (glutamine hydrolysing)
This is an abbreviated version!
For detailed information about CTP synthase (glutamine hydrolysing), go to the full flat file.
Word Map on EC 6.3.4.2
-
6.3.4.2
-
pyrimidine
-
cytosine
-
cytoophidia
-
dctp
-
cyclopentenyl
-
deoxycytidine
-
acivicin
-
glutamine-dependent
-
3-deazauridine
-
rheumatology
-
l-glutamine
-
alliance
-
carra
-
ctpas
-
pyrazofurin
-
uridine-cytidine
-
rheumatologist
-
6-diazo-5-oxo-l-norleucine
-
drug development
-
medicine
-
analysis
- 6.3.4.2
- pyrimidine
- cytosine
-
cytoophidia
- dctp
-
cyclopentenyl
- deoxycytidine
- acivicin
-
glutamine-dependent
- 3-deazauridine
-
rheumatology
- l-glutamine
-
alliance
-
carra
-
ctpas
- pyrazofurin
-
uridine-cytidine
-
rheumatologist
- 6-diazo-5-oxo-l-norleucine
- drug development
- medicine
- analysis
Reaction
Synonyms
CTP synthase, CTP synthase 1, CTP synthetase, CTP synthetase 1, CTPS, CTPS1, CTPS2, CTPsyn, CTS, cytidine 5'-triphosphate synthase, cytidine 5'-triphosphate synthetase, cytidine triphosphate synthetase, cytidine triphosphate synthetase 1, EcCTPS, pfCTP synthetase, PyrG, synthetase, cytidine triphosphate, URA7, uridine triphosphate aminase, UTP-ammonia ligase, UTP:ammonia ligase (ADP-forming)
ECTree
Advanced search results
KM Value
KM Value on EC 6.3.4.2 - CTP synthase (glutamine hydrolysing)
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
0.206
glutamine
wild-type protein, presence of 3 mM ATP, 2 mM UTP
0.345
glutamine
wild-type protein, presence of 1 mM ATP, 1 mM UTP
0.04
UTP
-
pH 8.0, 30°C, phosphorylated enzyme, in presence of 2 mM ATP
0.07
UTP
-
pH 8.0, mutant enzyme S354A, kinetic constant determined with 0.5 mM ATP
0.08
UTP
-
pH 8.0, 30°C, native enzyme or phosphorylated enzyme, in presence of 0.5 mM ATP
0.1
UTP
-
pH 8.0, mutant enzyme S330A, kinetic constant determined with 0.5 mM ATP
additional information
kinetic mechanism, activation and inhibition kinetics
-
additional information
additional information
-
kinetic mechanism, activation and inhibition kinetics
-
additional information
additional information
kinetics of wild-type and mutants
-
additional information
additional information
-
kinetics of wild-type and mutants
-
additional information
additional information
-
positive cooperativity for ATP and UTP
-
additional information
additional information
-
maximally active at physiological concentrations of ATP, GTP, and glutamine, whereas the Km and IC50 values for the substrate UTP and the product CTP, respectively, are close to their physiological concentrations
-
additional information
additional information
maximally active at physiological concentrations of ATP, GTP, and glutamine, whereas the Km and IC50 values for the substrate UTP and the product CTP, respectively, are close to their physiological concentrations
-