6.3.4.19: tRNAIle-lysidine synthase

This is an abbreviated version!
For detailed information about tRNAIle-lysidine synthase, go to the full flat file.

Reaction

Synonyms

lysidine synthetase, mesJ, MesJ protein, TilS, TilS protein, tRNAIle lysidine synthetase, tRNAIle-lysidine synthetase, yacA

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.4 Other carbon-nitrogen ligases

                6.3.4.19 tRNAIle-lysidine synthase

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Results	in table
43164	AA Sequence
3	Application
1	CAS Registry Number
7	Cloned(Commentary)
4	Crystallization (Commentary)
10	General Information
23	IC50 Value
23	Inhibitors
2	kcat/KM [mM/s]
33	KM Value [mM]
11	Natural Substrates/ Products (Substrates)
116	Organism
1	pH Optimum
14	Protein Variants
5	Purification (Commentary)
1	Reaction
16	Reference
27	Substrates and Products (Substrate)
2	Subunits
25	Synonyms
1	Systematic Name
7	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 6.3.4.19 - tRNAIle-lysidine synthase

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0176

(5R)-5-hydroxylysine

Escherichia coli

P52097

pH 8.5, 21°C

704642

0.0016 - 0.12

3-bromo-N-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

2 entries

0.0025

4,5-trans-dehydrolysine

Escherichia coli

P52097

pH 8.5, 21°C

704642

0.0016 - 0.062

4-(2-fluoro-5-methoxyanilino)-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one

2 entries

0.255

8-azaadenosine-5’-triphosphate

Escherichia coli

P52097

pH 8.5, 21°C

704642

0.000016

adenosine-5’-O-(1-thiotriphosphate)

Escherichia coli

P52097

pH 8.5, 21°C

704642

0.000035

alpha,beta-methylene-ATP

Escherichia coli

P52097

pH 8.5, 21°C

704642

0.000045

aminoethylcysteine

Escherichia coli

P52097

pH 8.5, 21°C

704642

0.0004

aminoethylserine

Escherichia coli

P52097

pH 8.5, 21°C

704642

0.105

benzimidazoleriboside-5’-triphosphate

Escherichia coli

P52097

pH 8.5, 21°C

704642

0.000082

beta,gamma-methyleneadenosine 5'-triphosphate

Escherichia coli

P52097

pH 8.5, 21°C

704642

0.91

cadaverine

Escherichia coli

P52097

pH 8.5, 21°C

704642

1.77

ethanolamine

Escherichia coli

P52097

pH 8.5, 21°C

704642

0.33

histamine

Escherichia coli

P52097

pH 8.5, 21°C

704642

0.62

lysinamide

Escherichia coli

P52097

pH 8.5, 21°C

704642

0.000085

mutated tRNAIle2

Escherichia coli

P52097

pH 8.5, 21°C, C34G-tRNAILe2

704642

-

0.0042 - 0.042

N-(3-methoxyphenyl)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

2 entries

0.0068

N-acetylethylenediamine

Escherichia coli

P52097

pH 8.5, 21°C

704642

1.3

N-alpha-methyl-lysine

Escherichia coli

P52097

pH 8.5, 21°C

704642

0.7

ornithine

Escherichia coli

P52097

pH 8.5, 21°C

704642

0.0016

3-bromo-N-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Escherichia coli

-

pH 8.5, temperature not specified in the publication

745394

0.12

3-bromo-N-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Pseudomonas aeruginosa

-

pH 8.5, temperature not specified in the publication

745394

0.0016

4-(2-fluoro-5-methoxyanilino)-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one

Escherichia coli

-

pH 8.5, temperature not specified in the publication

745394

0.062

4-(2-fluoro-5-methoxyanilino)-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one

Pseudomonas aeruginosa

-

pH 8.5, temperature not specified in the publication

745394

0.0042

N-(3-methoxyphenyl)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Escherichia coli

-

pH 8.5, temperature not specified in the publication

745394

0.042

N-(3-methoxyphenyl)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Pseudomonas aeruginosa

-

pH 8.5, temperature not specified in the publication

745394