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6.3.4.17: formate-dihydrofolate ligase

This is an abbreviated version!
For detailed information about formate-dihydrofolate ligase, go to the full flat file.

Reaction

ATP
+
formate
+
dihydrofolate
=
ADP
+
phosphate
+
10-formyldihydrofolate

Synonyms

Dihydrofolate formyltransferase, Formyl dihydrofolate synthase, Formyltransferase, dihydrofolate

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.4 Other carbon-nitrogen ligases
                6.3.4.17 formate-dihydrofolate ligase

Substrates Products

Substrates Products on EC 6.3.4.17 - formate-dihydrofolate ligase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + formate + dihydrofolate
ADP + phosphate + 10-formyldihydrofolate
show the reaction diagram