Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

6.3.4.15: biotin-[biotin carboxyl-carrier protein] ligase

This is an abbreviated version!
For detailed information about biotin-[biotin carboxyl-carrier protein] ligase, go to the full flat file.

Word Map on EC 6.3.4.15

Reaction

ATP
+
biotin
+
[biotin carboxyl-carrier protein]-L-lysine
=
AMP
+
diphosphate
+
[biotin carboxyl-carrier protein]-N6-biotinyl-L-lysine

Synonyms

Acetyl CoA holocarboxylase synthetase, Acetyl coenzyme A holocarboxylase synthetase, bacterial BirA biotin ligase, biotin acetyl-CoA carboxylase ligase, Biotin holoenzyme synthetase, biotin ligase, biotin protein ligase, Biotin--protein ligase, biotin-protein ligase, Biotin-[acetyl coenzyme A carboxylase] synthetase, Biotin-[acetyl-CoA carboxylase] synthetase, Biotin:apocarboxylase ligase, BirA, BirA protein, BPL, group I biotin protein ligase, HCS, Holocarboxylase synthetase, holocarboxylase synthetase 1, More, STK_15250, Synthetase, biotin-[acetyl coenzyme A carboxylase], yBL

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.4 Other carbon-nitrogen ligases
                6.3.4.15 biotin-[biotin carboxyl-carrier protein] ligase

KCat KM Value

KCat KM Value on EC 6.3.4.15 - biotin-[biotin carboxyl-carrier protein] ligase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.085
ATP
pH 8.0, 30°C
1050
biotin
-
wild-type, pH 8.3, 30°C
100 - 170
desthiobiotin
0.49
[Escherichia coli apo-biotin-carboxyl-carrier-protein mutant M136S]-L-lysine
-
pH 8.0, 37°C, wild type enzyme
-
15
[Escherichia coli apo-biotin-carboxyl-carrier-protein]-L-lysine
-
pH 8.0, 37°C, wild type enzyme
-
0.32 - 1.6
[Sulfolobus tokodaii apo-biotin-carboxyl-carrier-protein mutant S136M]-lysine
-
3.8 - 9.1
[Sulfolobus tokodaii apo-biotin-carboxyl-carrier-protein]-lysine
-