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6.3.4.10: biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase

This is an abbreviated version!
For detailed information about biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase, go to the full flat file.

Word Map on EC 6.3.4.10

Reaction

ATP
+
biotin
+
apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)]
=
AMP
+
diphosphate
+
[propionyl-CoA:carbon-dioxide ligase (ADP-forming)]

Synonyms

biotin protein ligase, Biotin-propionyl coenzyme A carboxylase synthetase, Biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] synthetase, BPL, HCS, HLCS, Holocarboxylase synthetase, Propionyl coenzyme A holocarboxylase synthetase, Synthetase, biotin-propionyl coenzyme A carboxylase

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.4 Other carbon-nitrogen ligases
                6.3.4.10 biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase

General Stability

General Stability on EC 6.3.4.10 - biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase

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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
after separation of the 64 kDa protein from an inert protein of 34 kDa on a nondenaturing PAGE, HCS is extremely labile and its enzymatic activity is totally lost within a few hours
-
loss of activity upon freezing
-