6.3.4.10: biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase

This is an abbreviated version!
For detailed information about biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase, go to the full flat file.

Word Map on EC 6.3.4.10

6.3.4.10

biotinylation

carboxylases

biotin-dependent

histone

biotinidase

acidosis

biotin-responsive

multivitamin

aciduria

biotinyl-5\'-amp

biotin-deficient

apocarboxylases

methylcitrate

3-hydroxyisovaleric

hyperammonemia

tokodaii

3-methylcrotonyl-coa

biotin-binding

diagnostics

medicine

analysis

synthesis

Reaction

apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)]

[propionyl-CoA:carbon-dioxide ligase (ADP-forming)]

Synonyms

biotin protein ligase, Biotin-propionyl coenzyme A carboxylase synthetase, Biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] synthetase, BPL, HCS, HLCS, Holocarboxylase synthetase, Propionyl coenzyme A holocarboxylase synthetase, Synthetase, biotin-propionyl coenzyme A carboxylase

ECTree

6 Ligases

6.3 Forming carbon-nitrogen bonds

6.3.4 Other carbon-nitrogen ligases

6.3.4.10 biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase

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Results	in table
38	AA Sequence
8	Application
1	CAS Registry Number
14	Cloned(Commentary)
8	Cofactor
827	Disease/ Diagnostics
1	Expression
17	General Information
2	General Stability
3	Inhibitors
14	KM Value [mM]
18	Localization
7	Metals/Ions
10	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
39	Organism
2	Pathway
4	pH Optimum
11	Protein Variants
7	Purification (Commentary)
1	Reaction
1	Reaction Type
38	Reference
25	Source Tissue
4	Specific Activity [micromol/min/mg]
2	Storage Stability
72	Substrates and Products (Substrate)
8	Subunits
41	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
2	Temperature Stability [°C]

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Cloned on EC 6.3.4.10 - biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase

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3 entries

expressed in HEK-293 cells

Homo sapiens

726859

expression in Escherichia coli

Drosophila melanogaster

716237

expression of HCS and HCS-green fluorescent protein fusion protein in HEK-293 cells

Homo sapiens

715997

expression of p67 and truncated HCS in Saccharomyces cerevisiae for interaction analysis in the two-hybrid system, overview. Usage of derivatives of Saccharomyces cerevisiae wild-type strain W303

Homo sapiens

705752

expression of the two His-tagged HCS isozymes in Escherichia coli strain Rosetta(DE3)

Homo sapiens

704561

fusion of full-length HCS to DNA adenine methyltransferase Dam and subsequent transfection into breast cancer cells MCF-7 and normal breast cells MCF-10A

Homo sapiens

713742

HCS fused to glutathione S-transferase, S-tag, and both N-terminal and C-terminal 6x His-tags

Homo sapiens

714763

HLCS is encoded by an 11-exon gene, HLCS, located on chromosome 21q22.1, genotyping

Homo sapiens

703282

transgenic HEK-293 cells that overexpress HCS fused to green fluorescent protein

Homo sapiens

715999