6.3.3.3: dethiobiotin synthase

This is an abbreviated version!
For detailed information about dethiobiotin synthase, go to the full flat file.

Reaction

Synonyms

BIO3, BioD, BioD1, Desthiobiotin synthetase, Dethiobiotin synthase, Dethiobiotin synthetase, DTB synthetase, DTBS, Synthetase, dethiobiotin

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.3 Cyclo-ligases

                6.3.3.3 dethiobiotin synthase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
23520	AA Sequence
1	CAS Registry Number
10	Cloned(Commentary)
1	Cofactor
12	Crystallization (Commentary)
9	IC50 Value
28	Inhibitors
3	Ki Value [mM]
43	KM Value [mM]
1	Localization
9	Metals/Ions
4	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
42	Organism
6	Pathway
158	PDB ID
2	pH Optimum
6	Protein Variants
9	Purification (Commentary)
7	Reaction
2	Reaction Type
42	Reference
2	Source Tissue
6	Specific Activity [micromol/min/mg]
2	Storage Stability
86	Substrates and Products (Substrate)
6	Subunits
16	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
28	Turnover Number [1/s]

KM Value

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

KM Value on EC 6.3.3.3 - dethiobiotin synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to KM Value Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.015 - 0.03

(7R,8S)-7,8-diaminopelargonic acid

5 entries

0.0013 - 0.045

7,8-diaminononanoate

3 entries

0.005 - 0.42

ATP

8 entries

3.4 - 10

CO2

2 entries

0.025 - 1.09

CTP

5 entries

0.026 - 1.56

GTP

5 entries

0.018

ITP

Mycobacterium tuberculosis

P9WPQ5

wild-type, pH 7.5, 37°C

746545

0.6

Mg2+

Escherichia coli

-

-

1334, 1337

40

MgCl2

Lysinibacillus sphaericus

-

-

1333

0.384 - 10.385

NaHCO3

5 entries

0.023

TTP

Mycobacterium tuberculosis

P9WPQ5

wild-type, pH 7.5, 37°C

746545

0.026

UTP

Mycobacterium tuberculosis

P9WPQ5

wild-type, pH 7.5, 37°C

746545

additional information

additional information

Escherichia coli

-

-

1340

-

0.015

(7R,8S)-7,8-diaminopelargonic acid

Escherichia coli

P13000

wild-type, pH 7.5, 37°C

746545

0.015

(7R,8S)-7,8-diaminopelargonic acid

Mycobacterium tuberculosis

P9WPQ5

mutant G169N, pH 7.5, 37°C

746545

0.018

(7R,8S)-7,8-diaminopelargonic acid

Escherichia coli

P13000

mutant N175G, pH 7.5, 37°C

746545

0.019

(7R,8S)-7,8-diaminopelargonic acid

Escherichia coli

P13000

mutant N175A, pH 7.5, 37°C

746545

0.03

(7R,8S)-7,8-diaminopelargonic acid

Mycobacterium tuberculosis

P9WPQ5

wild-type, pH 7.5, 37°C

746545

0.0013

7,8-diaminononanoate

Escherichia coli

-

-

1334, 1337

0.002

7,8-diaminononanoate

Mycobacterium tuberculosis

-

pH 7.5, temperature not specified in the publication

714208

0.045

7,8-diaminononanoate

Lysinibacillus sphaericus

-

-

1333

0.005

ATP

Escherichia coli

-

-

1334, 1337

0.01

ATP

Escherichia coli

P13000

wild-type, pH 7.5, 37°C

746545

0.012

ATP

Escherichia coli

P13000

mutant N175A, pH 7.5, 37°C

746545

0.017

ATP

Escherichia coli

P13000

mutant N175G, pH 7.5, 37°C

746545

0.022

ATP

Mycobacterium tuberculosis

P9WPQ5

mutant G169N, pH 7.5, 37°C

746545

0.029

ATP

Mycobacterium tuberculosis

-

pH 7.5, temperature not specified in the publication

714208

0.03

ATP

Mycobacterium tuberculosis

P9WPQ5

wild-type, pH 7.5, 37°C

746545

0.42

ATP

Lysinibacillus sphaericus

-

-

1333

3.4

CO2

Escherichia coli

-

-

1334, 1337

10

CO2

Lysinibacillus sphaericus

-

-

1333

0.025

CTP

Mycobacterium tuberculosis

P9WPQ5

wild-type, pH 7.5, 37°C

746545

0.045

CTP

Mycobacterium tuberculosis

P9WPQ5

mutant G169N, pH 7.5, 37°C

746545

0.391

CTP

Escherichia coli

P13000

mutant N175A, pH 7.5, 37°C

746545

0.869

CTP

Escherichia coli

P13000

mutant N175G, pH 7.5, 37°C

746545

1.09

CTP

Escherichia coli

P13000

wild-type, pH 7.5, 37°C

746545

0.026

GTP

Mycobacterium tuberculosis

P9WPQ5

wild-type, pH 7.5, 37°C

746545

0.101

GTP

Mycobacterium tuberculosis

P9WPQ5

mutant G169N, pH 7.5, 37°C

746545

1.09

GTP

Escherichia coli

P13000

mutant N175A, pH 7.5, 37°C

746545

1.387

GTP

Escherichia coli

P13000

mutant N175G, pH 7.5, 37°C

746545

1.56

GTP

Escherichia coli

P13000

wild-type, pH 7.5, 37°C

746545

0.384

NaHCO3

Escherichia coli

P13000

mutant N175G, pH 7.5, 37°C

746545

0.43

NaHCO3

Escherichia coli

P13000

mutant N175A, pH 7.5, 37°C

746545

0.6

NaHCO3

Escherichia coli

P13000

wild-type, pH 7.5, 37°C

746545

3.074

NaHCO3

Mycobacterium tuberculosis

P9WPQ5

wild-type, pH 7.5, 37°C

746545

10.385

NaHCO3

Mycobacterium tuberculosis

P9WPQ5

mutant G169N, pH 7.5, 37°C

746545