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6.3.2.9: UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase

This is an abbreviated version!
For detailed information about UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase, go to the full flat file.

Word Map on EC 6.3.2.9

Reaction

ATP
+
UDP-N-acetyl-alpha-D-muramoyl-L-alanine
+
D-glutamate
=
ADP
+
phosphate
+
UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate

Synonyms

D-Glutamate-adding enzyme, D-glutamic acid adding enzyme, D-Glutamic acid-adding enzyme, MurD, MurD cell wall enzyme, MurD ligase, Synthetase, uridine diphospho-N-acetylmuramoylalanyl-D-glutamate, UDP-Mur-Nac-L-Ala:L-Glu ligase, UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase, UDP-N-acetylmuramoyl-L-alanine:D-glutamateligase, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase, UDPMurNAc-L-alanine:D-glutamate ligase (ADP-forming), Uridine diphosphate N-acetylmuramoyl-L-alanine:D-glutamate ligase, Uridine diphospho-N-acetylmuramoylalanyl-D-glutamate synthetase

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.2 Acid—amino-acid ligases (peptide synthases)
                6.3.2.9 UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase

Substrates Products

Substrates Products on EC 6.3.2.9 - UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + 1-phospho-N-acetylmuramoyl-L-Ala + Glu
ADP + phosphate + 1-phospho-N-acetylmuramoyl-L-Ala-D-Glu
show the reaction diagram
-
-
-
-
?
ATP + dihydrouridine 5'-diphosphate-N-acetylmuramoyl-L-Ala + Glu
ADP + phosphate + dihydrouridine 5'-diphosphate-N-acetylmuramoyl-L-Ala-D-Glu
show the reaction diagram
-
-
-
-
?
ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanine + D-glutamate
ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate
show the reaction diagram
ATP + UDP-N-acetylmuramate-L-alanine
adenosine 5'-tetraphosphate
show the reaction diagram
ATP + UDP-N-acetylmuramate-L-alanine + D-glutamate
ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate
show the reaction diagram
ATP + UDP-N-acetylmuramoyl-L-Ala + (+/-)trans-1-amino-3-carboxy-cyclohexanecarboxylic acid
ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala-(+/-)trans-1-amino-3-carboxy-cyclohexanecarboxylic acid
show the reaction diagram
-
-
-
-
?
ATP + UDP-N-acetylmuramoyl-L-Ala + (+/-)trans-1-amino-3-carboxy-cyclopentanecarboxylic acid
ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala-(+/-)trans-1-amino-3-carboxy-cyclopentanecarboxylic acid
show the reaction diagram
-
-
-
-
?
ATP + UDP-N-acetylmuramoyl-L-Ala + alpha-methyl-DL-Glu
ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala-alpha-methyl-DL-Glu
show the reaction diagram
-
-
-
?
ATP + UDP-N-acetylmuramoyl-L-Ala + D-erythro-3-methylglutamic acid
ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala-D-erythro-3-methylglutamic acid
show the reaction diagram
-
-
-
-
?
ATP + UDP-N-acetylmuramoyl-L-Ala + D-erythro-4-methylglutamic acid
ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala-D-erythro-4-methylglutamic acid
show the reaction diagram
-
-
-
-
?
ATP + UDP-N-acetylmuramoyl-L-Ala + D-Glu
ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala-D-Glu
show the reaction diagram
-
-
-
-
?
ATP + UDP-N-acetylmuramoyl-L-Ala + DL-homocysteic acid
ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala-DL-homocysteic acid
show the reaction diagram
-
-
-
-
?
ATP + UDP-N-acetylmuramoyl-L-Ala + Glu
?
show the reaction diagram
ATP + UDP-N-acetylmuramoyl-L-Ala + Glu
ADP + phosphate + UDP-N-acetylmuramoyl-L-Ala-D-Glu
show the reaction diagram
ATP + UDP-N-acetylmuramyl-L-alanine + D-glutamate
ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate
show the reaction diagram
additional information
?
-