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6.3.2.8: UDP-N-acetylmuramate-L-alanine ligase

This is an abbreviated version!
For detailed information about UDP-N-acetylmuramate-L-alanine ligase, go to the full flat file.

Word Map on EC 6.3.2.8

Reaction

ATP
+
UDP-N-acetyl-alpha-D-muramate
+
L-alanine
=
ADP
+
phosphate
+
UDP-N-acetyl-alpha-D-muramoyl-L-alanine

Synonyms

Alanine-adding enzyme, alr5065, L-Ala ligase, L-Alanine adding enzyme, Mur ligase, MurB/CVs, MurC, MurC ligase, MurC synthetase, Synthetase, uridine diphospho-N-acetylmuramoylalanine, UDP-acetylmuramoyl-L-alanine synthetase, UDP-MurNAc:L-Ala ligase, UDP-MurNAc:L-alanine ligase, UDP-N-acetylenolpyruvoylglucosamine reductase/UDP-N-acetylmuramate: L-alanine ligase, UDP-N-acetylmuramate-alanine ligase, UDP-N-acetylmuramate:L-alanine ligase, UDP-N-acetylmuramic acid L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase, UDP-N-acetylmuramoyl:L-alanine ligase, UDP-N-acetylmuramoylalanine synthetase, UDP-N-acetylmuramyl:L-alanine ligase, UNAM:Ala ligase, Uridine 5´-diphosphate-N-acetylmuramyl-L-alanine synthetase, Uridine diphosphate N-acetylmuramate:L-alanine ligase, Uridine diphospho-N-acetylmuramoylalanine synthetase, Uridine-diphosphate-N-acetylmuramate:L-alanine ligase

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.2 Acid—amino-acid ligases (peptide synthases)
                6.3.2.8 UDP-N-acetylmuramate-L-alanine ligase

Molecular Weight

Molecular Weight on EC 6.3.2.8 - UDP-N-acetylmuramate-L-alanine ligase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
100000
dynamic light-scattering analysis
40000
-
gel filtration in absence and in presence of 2.5 mM 2-mercaptoethanol
50000
-
x * 50000, SDS-PAGE
51740
calculated
52000
-
x * 52000, recombinant detagged enzyme, SDS-PAGE
53630
-
mass spectrometry
53640
-
mass spectrometry
53750
-
trifluoroacetic adduct by mass spectrometry
53880
-
trifluoroacetic adduct by mass spectrometry
53990
-
trifluoroacetic adduct by mass spectrometry
54000
2 * 54000 by crystallographic analysis
54486
57760
65000
-
gel filtration of the recombinant enzyme