6.3.2.4: D-Alanine-D-alanine ligase
This is an abbreviated version!
For detailed information about D-Alanine-D-alanine ligase, go to the full flat file.
Word Map on EC 6.3.2.4
-
6.3.2.4
-
peptidoglycan
-
vancomycin
-
enterococci
-
d-cycloserine
-
vancomycin-resistant
-
faecium
-
d-alanyl-d-lactate
-
teicoplanin
-
depsipeptide
-
d-ala-d-lac
-
drug development
-
vanrs
-
atp-grasp
-
vancomycin-dependent
-
vand-type
-
d-ala-d-lactate
-
d-ala2
-
analysis
-
synthesis
- 6.3.2.4
- peptidoglycan
- vancomycin
-
enterococci
- d-cycloserine
-
vancomycin-resistant
- faecium
-
d-alanyl-d-lactate
- teicoplanin
-
depsipeptide
- d-ala-d-lac
- drug development
-
vanrs
-
atp-grasp
-
vancomycin-dependent
-
vand-type
- d-ala-d-lactate
-
d-ala2
- analysis
- synthesis
Reaction
Synonyms
AbDDL, ATP-dependent D-Ala:D-Ala ligase, BBR47_20440, BMD_0213, BMQ_0219, BMWSH_5013, D-Ala-D-Ala ligase, D-Ala-D-Ala synthetase, D-Ala:D-Ala ligase, D-alanine:D-alanine (D-lactate) ligase (ADP), D-Alanine:D-alanine ligase, D-alanyl-D-alanine ligase B, D-Alanyl-D-alanine synthetase, D-Alanylalanine synthetase, DD1, DDI, Ddl, DdlA, DdlB, DdlB ligase, dll, dllB, EcDdlB, More, Rv2981c, SsDdl, Synthetase, D-alanylalanine, Tb-DdlA, TmDdl, TtDdL, TTHA1587, VanA, VanB ligase, YpDDL
ECTree
6.3.2.4 D-Alanine-D-alanine ligaseAdvanced search results
results (
results (KM Value
KM Value on EC 6.3.2.4 - D-Alanine-D-alanine ligase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
KM VALUE [mM] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.003
D-alanine
37°C, KM-value for D-alanine1 (the first molecule of substrate that is activated by the enzyme molecule) , wild-type enzyme, pH 7.5
0.004
D-alanine
37°C, KM-value for D-alanine1 (the first molecule of substrate that is activated by the enzyme molecule), wild-type enzyme, pH 9.2
0.11
D-alanine
37°C, KM-value for D-alanine1 (the first molecule of substrate that is activated by the enzyme molecule), wild-type enzyme, pH 6.0
0.51
D-alanine
37°C, KM-value for D-alanine1 (the first molecule of substrate that is activated by the enzyme molecule), mutant enzyme E15Q, pH 7.5
0.51
D-alanine
37°C, KM-value for D-alanine1 (the first molecule of substrate that is activated by the enzyme molecule), mutant enzyme E15Q, pH 9.2
0.85
D-alanine
37°C, KM-value for D-alanine1 (the first molecule of substrate that is activated by the enzyme molecule), mutant enzyme S150A, pH 7.5
1.011
D-alanine
pH 8.0, 37°C, recombinant His-tagged enzyme
1.1
D-alanine
37°C, KM-value for D-alanine2 (the second molecule of substrate that is activated by the enzyme molecule), wild-type enzyme, pH 9.2
2
D-alanine
37°C, KM-value for D-alanine2 (the second molecule of substrate that is activated by the enzyme molecule), wild-type enzyme, pH 7.5
4.8
D-alanine
37°C, KM-value for D-alanine1 (the first molecule of substrate that is activated by the enzyme molecule), mutant enzyme Y216F, pH 9.2
6.2
D-alanine
37°C, KM-value for D-alanine1 (the first molecule of substrate that is activated by the enzyme molecule), mutant enzyme S150A, pH 6.0
8
D-alanine
37°C, KM-value for D-alanine2 (the second molecule of substrate that is activated by the enzyme molecule), wild-type enzyme, pH 6.0
11
D-alanine
37°C, KM-value for D-alanine1 (the first molecule of substrate that is activated by the enzyme molecule), mutant enzyme E15Q, pH 6.0
16
D-alanine
37°C, KM-value for D-alanine1 (the first molecule of substrate that is activated by the enzyme molecule), mutant enzyme Y216F, pH 7.5
44
D-alanine
37°C, KM-value for D-alanine1 (the first molecule of substrate that is activated by the enzyme molecule) , mutant enzyme S150A, pH 9.2
65
D-alanine
37°C, KM-value for D-alanine2 (the second molecule of substrate that is activated by the enzyme molecule), mutant enzyme E15Q, pH 9.2
74
D-alanine
37°C, KM-value for D-alanine2 (the second molecule of substrate that is activated by the enzyme molecule), mutant enzyme E15Q, pH 7.5
80
D-alanine
37°C, KM-value for D-alanine2 (the second molecule of substrate that is activated by the enzyme molecule), mutant enzyme S150A, pH 7.5
82
D-alanine
37°C, KM-value for D-alanine2 (the second molecule of substrate that is activated by the enzyme molecule), mutant enzyme E15Q, pH 6.0
140
D-alanine
37°C, KM-value for D-alanine2 (the second molecule of substrate that is activated by the enzyme molecule), mutant enzyme S150A, pH 6.0
150
D-alanine
37°C, KM-value for D-alanine1 (the first molecule of substrate that is activated by the enzyme molecule) , mutant enzyme Y216F, pH 6.0
450
D-alanine
37°C, KM-value for D-alanine2 (the second molecule of substrate that is activated by the enzyme molecule), mutant enzyme Y216F, pH 6.0
630
D-alanine
37°C, KM-value for D-alanine2 (the second molecule of substrate that is activated by the enzyme molecule), mutant enzyme Y216F, pH 7.5
1100
D-alanine
37°C, KM-value for D-alanine2 (the second molecule of substrate that is activated by the enzyme molecule), mutant enzyme S150A, pH 9.2
1200
D-alanine
37°C, KM-value for D-alanine2 (the second molecule of substrate that is activated by the enzyme molecule), mutant enzyme Y216F, pH 9.2
additional information
additional information
steady-state kinetics
-
additional information
additional information
-
steady-state kinetics
-
additional information
additional information
kinetics of wild-type and mutant enzymes
-
additional information
additional information
-
kinetics of wild-type and mutant enzymes
-
additional information
additional information
Michaelis-Menten steady-state kinetics
-
additional information
additional information
-
Michaelis-Menten steady-state kinetics
-
additional information
additional information
steady-state kinetics of ATP hydrolysis
-
additional information
additional information
-
steady-state kinetics of the Michaelis-Menten equation with a single binding site
-
