6.3.2.32: coenzyme gamma-F420-2:alpha-L-glutamate ligase

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For detailed information about coenzyme gamma-F420-2:alpha-L-glutamate ligase, go to the full flat file.

Reaction

Synonyms

CofF, CofF protein, gamma-F420-2:alpha-L-glutamate ligase, MJ1001

ECTree

6 Ligases

6.3 Forming carbon-nitrogen bonds

6.3.2 Acid—amino-acid ligases (peptide synthases)

6.3.2.32 coenzyme gamma-F420-2:alpha-L-glutamate ligase

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2	Activating Compound
42	AA Sequence
1	Cloned(Commentary)
3	Inhibitors
1	KM Value [mM]
2	Metals/Ions
3	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
1	Organism
5	Pathway
1	pH Optimum
1	Purification (Commentary)
1	Reaction
1	Reference
4	Substrates and Products (Substrate)
2	Subunits
4	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Stability [°C]

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Natural Substrates Products on EC 6.3.2.32 - coenzyme gamma-F420-2:alpha-L-glutamate ligase

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ATP + coenzyme gamma-F420-2 + L-glutamate

ADP + phosphate + coenzyme alpha-F420-3

Methanocaldococcus jannaschii

Q58407

the enzyme caps the gamma-glutamyl tail of the hydride carrier coenzyme F420. CofF specifically adds an alpha-linked glutamate to gamma-F420-2 produced by the Methanococcus jannaschii CofE protein. Coenzyme F420-2 is coenzyme F420 with two glutamic acid residue, coenzyme F420-3 is coenzyme F420 with three glutamic acid residues

700925