6.3.2.31: coenzyme F420-0:L-glutamate ligase
This is an abbreviated version!
For detailed information about coenzyme F420-0:L-glutamate ligase, go to the full flat file.
Word Map on EC 6.3.2.31
Reaction
Synonyms
bifunctional F420 biosynthesis protein FbiB, BQ2027_MB3290, CofE, CofE-AF, F420-0:gamma-glutamyl ligase, FbiB, MJ0768
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Natural Substrates Products on EC 6.3.2.31 - coenzyme F420-0:L-glutamate ligase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
GTP + coenzyme F420-0 + L-glutamate
GDP + phosphate + coenzyme F420-1
reduced coenzyme F420 (F420H2) is the true substrate of F420-0-gamma-glutamyl ligase for the attachment of more than two glutamate residues to the coenzyme
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GTP + coenzyme F420-0 + L-glutamate
GDP + phosphate + coenzyme F420-1
reduced coenzyme F420 (F420H2) is the true substrate of F420-0-gamma-glutamyl ligase for the attachment of more than two glutamate residues to the coenzyme
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L-glutamate + GTP + coenzyme F420-0
GDP + phosphate + coenzyme gamma-F420-1
the enzyme protein catalyzes two distinct and independent reactions, firstly attaching a glutamte via its alpha-NH2 to F420-0. The second reaction (cf. coenzyme F420-1:gamma-glutamyl ligase) is a gamma ligation, taking place when a certain amount of monoglutamylated F420-1 has accumulated
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L-glutamate + GTP + coenzyme F420-0
GDP + phosphate + coenzyme gamma-F420-1
step in the biosynthesis of coenzyme F420
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