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6.3.2.26: N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase

This is an abbreviated version!
For detailed information about N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase, go to the full flat file.

Word Map on EC 6.3.2.26

Reaction

3 ATP +

L-2-aminohexanedioate
+
L-cysteine
+
L-valine
+
H2O
= 3 AMP + 3 diphosphate +
N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine

Synonyms

ACV synthetase, ACVS, DELTA-(alpha-aminoadipyl)cysteinylvaline synthetase, delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase, delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase, delta-(L-alpha-aminoadipyl-L-cysteinyl-D-valine synthetase), delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase, L-(alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase, L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase, L-delta-alpha-aminoadipoyl-L-cysteinyl-D-valine synthetase, phosphopantothenate synthetase, Pps, synthetase, delta-(alpha-aminoadipyl)cysteinylvaline, TK1686

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.2 Acid—amino-acid ligases (peptide synthases)
                6.3.2.26 N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase

Molecular Weight

Molecular Weight on EC 6.3.2.26 - N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
220000
-
gel filtration
283000
-
subunit of Streptomyces clavuligerus ACVS
32000
-
subunit of Streptomyces clavuligerus ACVS
400000
-
1 * 400000, SDS-PAGE
404100
411500
-
calculation from amino acid sequence
414800
-
calculation from amino acid sequence
422500
-
calculation from DNA-sequence, PAGE and gel filtration
424100
-
calculation from amino acid sequence
425000
-
gel filtration
430000
-
gel filtration
470000
-
gradient PAGE
560000
-
monomer of Streptomyces clavuligerus ACVS that appears as a 500kDa band in SDS-PAGE